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青海省棘球蚴病流行與分布情況調(diào)查

發(fā)布時(shí)間:2018-06-08 19:48

  本文選題:棘球蚴病 + 流行病學(xué)。 參考:《中國寄生蟲學(xué)與寄生蟲病雜志》2017年05期


【摘要】:目的了解和掌握青海省人體棘球蚴病流行與分布情況。方法于2012年3-9月在青海省43個(gè)縣(市、區(qū))按牧區(qū)、半農(nóng)牧區(qū)、農(nóng)區(qū)和城鎮(zhèn)進(jìn)行分層,根據(jù)各層人口數(shù)占全縣(市、區(qū))人口總數(shù)的比例確定各層調(diào)查人數(shù)及調(diào)查村數(shù),對(duì)3周歲以上常住居民進(jìn)行B超檢查,開展人群棘球蚴患病情況調(diào)查;每層抽取1所小學(xué),或者在學(xué)校集中的縣城抽取全縣所有小學(xué),對(duì)6~13歲學(xué)生進(jìn)行腹腔B超檢查,同時(shí)采集靜脈血,用ELISA試劑盒檢測血清抗棘球蚴Ig G抗體水平。應(yīng)用SPSS17.0軟件對(duì)調(diào)查結(jié)果進(jìn)行統(tǒng)計(jì)學(xué)分析,計(jì)算患病檢出率和血清抗體陽性率,率間的比較采用χ~2檢驗(yàn)。結(jié)果青海省43個(gè)縣(市、區(qū))共抽取683個(gè)行政村(社區(qū)),B超檢查121 683人,檢出棘球蚴病患者1 333例,平均患病檢出率為1.10%(1 333/121 683)。人群調(diào)查結(jié)果顯示,不同生產(chǎn)類型的牧區(qū)、半農(nóng)牧區(qū)、農(nóng)區(qū)、城鎮(zhèn)的患病檢出率依次為2.51%(1 101/43 822)、0.84%(111/13 228)、0.08%(30/38 882)和0.35%(91/25 751)。性別分布中,男、女患病檢出率分別為0.90%(526/58 348)、1.27%(807/63 335),差異有統(tǒng)計(jì)學(xué)意義(χ~2=38.93,P0.01);年齡分布中,以30~39歲青壯年人群患病檢出率最高,為1.51%(387/25 682),不同年齡組間患病檢出率差異有統(tǒng)計(jì)學(xué)意義(χ~2=80.84,P0.01);調(diào)查對(duì)象來自于14個(gè)民族,其中1 333例患者主要分布于藏族、漢族、回族、蒙古族和撒拉族,這5個(gè)民族的患病檢出率分別為2.25%(1 277/56 752)、0.07%(32/44 420)、0.01%(1/8 229)、0.25%(17/6 806)和0.04%(1/2 558),各民族患病檢出率間差異有統(tǒng)計(jì)學(xué)意義(χ~2=1 354.77,P0.01);職業(yè)分布中以宗教人士的患病檢出率最高,為5.08%(52/1 024),牧民次之,為2.42%(1 089/44 982)。共抽取小學(xué)191所,均來自學(xué)校集中的縣城,B超檢查學(xué)生47 747人,檢出棘球蚴病者253例,平均患病檢出率為0.53%(253/47 747);ELISA檢測45 507份血清,陽性者2 693份,血清抗體陽性率為5.92%。結(jié)論青海南部各縣是棘球蚴病流行嚴(yán)重的地區(qū)。
[Abstract]:Objective to understand the prevalence and distribution of human echinococcosis in Qinghai province. Methods from March to September 2012, 43 counties (cities, districts) in Qinghai Province were divided into pastoral areas, semi-agricultural pastoral areas, agricultural areas and towns. According to the proportion of the population of each layer to the total population of the whole county (city and district), the investigation population and the number of villages were determined. B ultrasound examination was carried out on residents over 3 years of age, and an investigation was carried out on the prevalence of echinococcosis in the population. One primary school was selected from each level, or all primary schools in the county where the school was concentrated, and abdominal B ultrasound was performed on 6- and 13-year-old students. At the same time, venous blood was collected and the serum level of IgG antibody against echinococcus was detected by Elisa kit. SPSS 17.0 software was used to analyze the results of the investigation. The prevalence rate and the positive rate of serum antibody were calculated, and 蠂 ~ 2 test was used to compare the rates. Results A total of 683 administrative villages were selected from 43 counties (cities and districts) in Qinghai Province (community, B ultrasound examination, 121 683 people), 1 333 patients with echinococcosis were detected, the average prevalence rate was 1. 10% 1333 / 121 883. The results of crowd survey showed that the prevalence rate of disease in pastoral areas of different production types, semi-agricultural and pastoral areas, agricultural areas and towns was 2.5110 1 / 43 822% 0.844% and 0.35% 91 / 25 751 respectively. In the sex distribution, the prevalence rate of male and female was 0.90 / 526 / 58 348 / 1.27 respectively. The difference was statistically significant (蠂 ~ (2 / 2) 38.93) P 0.01.The age distribution was the highest in 30 ~ 39 years of age. There was a significant difference in the prevalence rate among different age groups (蠂 ~ (2 / 2) 80.84) (P < 0.01). The subjects were from 14 nationalities, of which 1 333 patients were mainly Tibetan, Han, Hui, Mongolian and Salah. The prevalence rates of these five ethnic groups were 2.25 / 127 / 56 / 7522 / 0.07 and 32 / 44 / 44 / 420 / 0.01 / 1 / 8 / 2290.25 / 6 / 6 806) and 0.04% / 2 558, respectively. There were statistically significant differences between the prevalence rates of each ethnic group (蠂 2 1 354.77 P 0.01; the highest prevalence rate was 5. 08% 522 024) among the religious people in the occupational distribution, followed by the herdsman at 2. 42% 10 / 89 4 / 98 2. A total of 191 primary schools were selected, all of them were from the county towns where the schools were concentrated. There were 253 cases of echinococcosis detected by B-mode ultrasonography. The average detection rate was 0.53 / 25 / 47,7470.The average positive rate was 45 507 serum samples, 2 693 samples were positive, and the positive rate of serum antibody was 5.92%. Conclusion Echinococcosis is prevalent in southern counties of Qinghai Province.
【作者單位】: 青海省地方病預(yù)防控制所;
【分類號(hào)】:R181.3;R532.32

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