小米對(duì)高血糖小鼠保健功能及輔助療效研究
本文選題:小米 + 小白鼠; 參考:《河北北方學(xué)院》2017年碩士論文
【摘要】:以高血糖小白鼠為試驗(yàn)對(duì)象,在基礎(chǔ)飼料中添加不同比例的小米,與基礎(chǔ)飼料和大米作對(duì)照,研究小米對(duì)高血糖小白鼠空腹血糖值、健康狀況和生命活力的影響。試驗(yàn)表明:1.在基礎(chǔ)飼料中添加不同比例的小米或大米飼喂高血糖小白鼠,對(duì)小白鼠的采食量和體重沒有影響。2.用小米部分替代基礎(chǔ)飼料,可以明顯抑制高血糖小白鼠空腹血糖值的升高趨勢(shì)。隨著小米在飼料中所占比例的提高,抑制效果逐漸加強(qiáng),當(dāng)小米比例達(dá)到80%時(shí),飼喂30天小白鼠空腹血糖值下降4.6%,基礎(chǔ)對(duì)照升高7.1%;用大米替代基礎(chǔ)飼料,隨著大米添加比例的增加,高血糖小白鼠血糖值的升高幅度越來越大。當(dāng)大米比例達(dá)到80%時(shí),小白鼠空腹血糖值升高23.7%。3.采用胰島素治療高血糖小白鼠,用80%比例的小米替代基礎(chǔ)飼料,可以顯著提高療效。給藥30天后,飼喂基礎(chǔ)飼料的小白鼠空腹血糖值升高5.2%,而飼喂小米的試驗(yàn)組僅升高2.7%。4.飼喂含小米飼料的小白鼠,精神狀態(tài)良好,飲食情況正常,皮毛光亮,作息時(shí)間較為規(guī)律,行動(dòng)靈活;飼喂含不同比例大米的小白鼠精神狀況不佳,明顯嗜睡,毛發(fā)稀疏且光澤變暗,其中,20%、40%比例大米組有輕微的脫毛現(xiàn)象;60%、80%比例大米組有嚴(yán)重的脫毛現(xiàn)象,背部、腹部均有不愈合的血塊;飼喂基礎(chǔ)飼料或在基礎(chǔ)飼料中添加不同比例的大米,均有死亡情況發(fā)生,其中基礎(chǔ)飼料組死亡率40%,80%大米組死亡率50%,而所有小米組死亡率為0。試驗(yàn)表明,在基礎(chǔ)飼料中添加一定比例小米,可以明顯改善高血糖小白鼠的健康狀況,維持正常的生命活力;在基礎(chǔ)飼料中添加大米,高血糖小白鼠的健康狀況不好,生命活力下降。5.用80%比例的小米替代基礎(chǔ)飼料與基礎(chǔ)飼料組對(duì)比,在試驗(yàn)期30天內(nèi),小白鼠的糖耐量沒有差異。
[Abstract]:The effects of millet on fasting blood glucose level, health status and vitality of hyperglycemic mice were studied by adding different proportions of millet into basic diet and compared with basic diet and rice. The experiment shows that 1: 1. Adding different proportion of millet or rice to the basic diet did not affect the feed intake and body weight of the mice. The increasing trend of fasting blood glucose in hyperglycemic mice could be obviously inhibited by replacing basic diet with millet. With the increase of millet proportion in feed, the inhibition effect was gradually strengthened. When millet ratio reached 80, the fasting blood glucose value of mice fed for 30 days decreased 4.6, and the basal control increased 7.1%. With the increase of the proportion of rice, the increase of blood glucose in hyperglycemic mice was more and more. When the rice ratio reached 80, the fasting blood glucose of the mice increased 23. 7% and 3. 3%. Using insulin to treat hyperglycemic mice and replacing basic diet with 80% millet can significantly improve the curative effect. After 30 days of administration, the fasting blood glucose level of the mice fed basic diet increased by 5.2 and 2.7.4in the test group fed millet. The mice fed with millet feed had a good mental state, a normal diet, a bright fur, a regular schedule and flexible actions; the mice fed with different proportions of rice were in poor mental condition and were obviously drowsiness. The hair was sparse and the gloss was darkened. There was slight depilation in the rice group (40%) and severe depilation in the rice group (60% / 80%). There were blood clots in the back and abdomen. The mortality rate of basic diet group was 40% 80% rice group was 50%, while that of all millet group was 0%. The experiment shows that adding a certain proportion of millet to the basic diet can obviously improve the health status of the hyperglycemic mice and maintain the normal life vigor, and the health condition of the hyperglycemic mice is not good when rice is added to the basic diet. Decline in vitality. There was no difference in glucose tolerance between the basic diet group and the basal diet group, which was replaced by 80% millet in 30 days.
【學(xué)位授予單位】:河北北方學(xué)院
【學(xué)位級(jí)別】:碩士
【學(xué)位授予年份】:2017
【分類號(hào)】:R151
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