本文選題：代謝綜合征 + 患病率　； 參考：《皖南醫(yī)學(xué)院》2017年碩士論文

【摘要】：目的了解某社區(qū)體檢人群代謝綜合征(metabolic syndrome,MS)的患病率及其影響因素,為本地區(qū)代謝綜合征的綜合防治提供科學(xué)依據(jù)。方法采用整群抽樣的方法,以某社區(qū)參加健康體檢的18歲以上成人作為研究對(duì)象進(jìn)行問(wèn)卷調(diào)查、體格檢查和實(shí)驗(yàn)室檢查,采用非條件Logistic回歸分析MS的相關(guān)影響因素。結(jié)果1.收集信息完整的研究對(duì)象610名,其中男性334人(54.8%),女性276人(45.2%)。按照CDS診斷標(biāo)準(zhǔn),有82人被檢出患有MS,患病率為13.4%,男女患病率分別為15.6%(52/334)和10.9%(30/276),差異無(wú)統(tǒng)計(jì)學(xué)意義。2.年齡大、文化程度低、具有高血壓或糖尿病家族史、疏于鍛煉或鹽攝入過(guò)多的研究對(duì)象MS患病率均高于對(duì)照組。MS患病率隨年齡的增長(zhǎng)而上升(18~44歲、45~59歲和60歲以上者患病率分別7.5%(19/252)、16.5%(33/200)和19.0%(30/158);小學(xué)及以下、中學(xué)/中專(zhuān)和大專(zhuān)及以上患病率分別為19.4%(28/144)、13.3%(26/195)和10.3%(28/271);有無(wú)食鹽攝入過(guò)多的患病率分別為11.5%(54/469)和19.9%(28/141);有無(wú)每周鍛煉2次以上的生活習(xí)慣的患病率分別為17.2%(55/319)、9.3%(27/291);有無(wú)高血壓家族史的患病率分別為9.8%(49/499)和29.7%(33/111);有無(wú)糖尿病家族史的患病率分別為11.2%(61/545)和32.3%(21/65),差異均具有統(tǒng)計(jì)學(xué)意義(P0.05)。而病例與對(duì)照兩組患病率在職業(yè)、經(jīng)濟(jì)收入、有無(wú)吸煙史、有無(wú)紅肉攝入過(guò)多的分布上差異無(wú)統(tǒng)計(jì)學(xué)意義。3.MS各組分按患病率高低依次為肥胖30.3%(185/610)、高血壓22.6%(138/610)、高血糖16.6%(101/610)、高TG25.4%(155/610)、低HDL-C8.7%(53/610)。MS中肥胖+高血壓+血脂異常是最常見(jiàn)的組合(占34.1%)。除了低HDL-C檢出率女性高于男性,肥胖、高TG血癥、高血壓、高血糖檢出率均為男性高于女性。4.除了HDL-C水平低于對(duì)照組,MS患者的BMI、WC等體檢及實(shí)驗(yàn)室檢測(cè)指標(biāo)均高于對(duì)照組。5.MS患者的RDW-CV明顯高于對(duì)照組(P0.05)。MS各組分中高血糖組和低HDL-C組的RDW-CV檢測(cè)值高于對(duì)照組,差異有統(tǒng)計(jì)學(xué)意義,但是RDW-CV在其他組分中的分布未見(jiàn)明顯差異。6.多因素Logistic回歸分析結(jié)果顯示年齡增大[OR=1.049(1.003-1.098)]、具有糖尿病家族史[OR=0.356(0.132-0.784)]、體質(zhì)指數(shù)高[OR=1.241(1.088-1.426)]、腰圍粗[OR=1.048(1.001-1.097)]、高血壓[OR=1.040(1.017-1.063)]、高甘油三酯[OR=2.504(1.881-3.335)]和低HDL-C[OR=0.323(0.138-0.755)]是MS的危險(xiǎn)因素。結(jié)論社區(qū)體檢人群具有相當(dāng)比例的個(gè)體患有MS,應(yīng)針對(duì)相關(guān)危險(xiǎn)因素及早采取綜合防治措施,提高自我健康管理意識(shí),增強(qiáng)運(yùn)動(dòng),預(yù)防超重和肥胖,合理膳食(減少食鹽和紅肉攝入量)對(duì)于預(yù)防與控制MS的發(fā)生和發(fā)展,降低心腦血管疾病的發(fā)病和死亡風(fēng)險(xiǎn),具有重要意義。目的代謝綜合征(MS)增加了心血管疾病、2型糖尿病(DM)和其他慢性疾病的患病風(fēng)險(xiǎn)。為了更好地控制代謝綜合征,全面了解代謝綜合征的流行現(xiàn)狀是必要的。但是,在研究中對(duì)于不同的中國(guó)人群,代謝綜合征患病率各不相同。本研究的目的是系統(tǒng)地評(píng)估中國(guó)代謝綜合征的患病率。方法通過(guò)Pub Med、Springer和Elsevier等數(shù)據(jù)庫(kù)檢索,收集發(fā)表于2011年1月至2015年12月的相關(guān)英文文獻(xiàn)。根據(jù)不同的診斷標(biāo)準(zhǔn),利用Meta分析估計(jì)代謝綜合征患病率。采用固定效應(yīng)模型或隨機(jī)效應(yīng)模型進(jìn)行合并亞組分析,并進(jìn)行發(fā)表偏倚的檢查和敏感性分析。結(jié)果共納入文獻(xiàn)37篇,包括23個(gè)鄉(xiāng)村或城市的研究和14個(gè)省為基礎(chǔ)的研究。不同的診斷標(biāo)準(zhǔn),合并代謝綜合征發(fā)病率不同,以鄉(xiāng)村或城市為基礎(chǔ)的研究,NCEP-ATPIII為30.6%(23.6-37.7),IDF為27.5%(23.4-31.6),JIS為36.5%(29.0-44.1);以省為基礎(chǔ)的研究,NCEP-ATPIII為24.9%(22.0-27.8),IDF為22.7%(13.5-31.9),JIS為24.4%(20.5-28.8)。基于三個(gè)標(biāo)準(zhǔn),亞組分析顯示女性代謝綜合征的患病率高于男性。根據(jù)NCEP-ATPⅢ和IDF,在城市居民代謝綜合征患病率高于農(nóng)村。然而,基于JIS得到相反的結(jié)果。敏感性分析表明,合并的患病率保持穩(wěn)定。結(jié)論這項(xiàng)mata分析顯示,依據(jù)不同的診斷標(biāo)準(zhǔn),中國(guó)成人代謝綜合征患病率處于上升趨勢(shì),接近歐美國(guó)家水平。我們應(yīng)該制定有效的公共衛(wèi)生策略,預(yù)防代謝綜合征,以減少中國(guó)的醫(yī)療負(fù)擔(dān)。
[Abstract]:Objective to understand the prevalence and influencing factors of metabolic syndrome (MS) in a community physical examination population, and to provide a scientific basis for the comprehensive prevention and treatment of metabolic syndrome in the local area. The correlation factors of MS were analyzed by unconditional Logistic regression. Results 1. of the 610 subjects were collected, including 334 men (54.8%) and 276 women (45.2%). According to the CDS diagnostic criteria, 82 people were detected with MS, the prevalence rate was 13.4%, and the prevalence rates of men and women were 15.6% (52/334) and 10.9% (30/276), and the difference was not Statistical significance was.2. age, low education level, family history of hypertension or diabetes, and the prevalence rate of MS was higher than that of the control group. The prevalence rate of.MS was higher than that in the control group (18~44 years, 45~59 years and above 60 years old, respectively, 7.5% (19/252), 16.5% (33/200) and 19% (30/158), and primary school and the same. The prevalence rates were 19.4% (28/144), 13.3% (26/195) and 10.3% (28/271), respectively, and 11.5% (54/469) and 19.9% (28/141) for excessive intake of salt, and 17.2% (55/319), 9.3% (27/291), and the prevalence rate of family history of hypertension. 9.8% (49/499) and 29.7% (33/111), respectively, the prevalence rates of family history of diabetes were 11.2% (61/545) and 32.3% (21/65), and the differences were statistically significant (P0.05). The two groups of cases and control cases were in occupational, economic income, smoking history, and the distribution of excessive intake of red meat was not statistically significant,.3.MS components were not statistically significant The prevalence rate was 30.3% (185/610), hypertension 22.6% (138/610), hyperglycemia 16.6% (101/610), high TG25.4% (155/610), low HDL-C8.7% (53/610).MS, obesity + hypertension + blood lipid abnormality (34.1%). In addition to low HDL-C detection rate, women were higher than men, obesity, high TG, hypertension, and high blood sugar were all male The sex of.4. was higher than that of the control group. The BMI, WC and other physical examination indexes of the patients with MS were higher than those of the control group. The RDW-CV of the.5.MS patients was higher than that of the control group (P0.05). The RDW-CV detection values in the hyperglycemic group and the low HDL-C group were higher than those in the control group. The difference was statistically significant, but the RDW-CV was in the other components. The distribution of.6. multiple factor Logistic regression analysis showed that age increased [OR=1.049 (1.003-1.098)], with family history of diabetes [OR=0.356 (0.132-0.784), high [OR=1.241 (1.088-1.426) of body mass index], low waistline [OR=1.048 (1.001-1.097)], high blood pressure [OR=1.040 (1.017-1.063)], high triglyceride] And low HDL-C[OR=0.323 (0.138-0.755)] is a risk factor for MS. Conclusion a considerable proportion of individuals with MS in community physical examination people should be taken early to adopt comprehensive prevention and control measures to improve self-health management awareness, enhance exercise, prevent overweight and obesity, reasonable diet (reducing salt and red meat intake) for prevention and treatment. It is of great significance to control the occurrence and development of MS and reduce the risk of death and death of cardiovascular and cerebrovascular diseases. Objective metabolic syndrome (MS) increases the risk of cardiovascular disease, type 2 diabetes (DM) and other chronic diseases. To better control the metabolic syndrome, it is necessary to understand the prevalence of metabolic syndrome in a full face. In the study, the prevalence rates of metabolic syndrome were different for different Chinese people. The purpose of this study was to systematically assess the prevalence of metabolic syndrome in China. Methods through Pub Med, Springer, and Elsevier databases, the relevant English literature published from January 2011 to December 2015 was collected. According to different diagnostic criteria, Meta analysis was used to estimate the prevalence of metabolic syndrome. The combined subgroup analysis was performed with a fixed effect model or a random effect model, and the bias examination and sensitivity analysis were conducted. The results were included in 37 literature, including 23 rural or urban studies and 14 provinces based research. Different diagnostic criteria, combined with metabolic syndrome. The incidence was different in rural or urban based studies, NCEP-ATPIII was 30.6% (23.6-37.7), IDF was 27.5% (23.4-31.6), JIS was 36.5% (29.0-44.1); NCEP-ATPIII was 24.9% (22.0-27.8), IDF was 22.7% (13.5-31.9), JIS was 24.4% (20.5-28.8). The subgroup analysis showed the prevalence of female metabolic syndrome based on three criteria. The prevalence rate of metabolic syndrome in urban residents was higher than that in the rural areas based on NCEP-ATP III and IDF. However, the adverse results based on JIS showed that the incidence of the combined disease remained stable. Conclusion this Mata analysis showed that the prevalence rate of metabolic syndrome in Chinese adults was on the rise, according to the different diagnostic criteria, and the prevalence rate of Chinese adult metabolic syndrome was on the rise. We should develop effective public health strategies to prevent metabolic syndrome, so as to reduce China's medical burden.

【學(xué)位授予單位】：皖南醫(yī)學(xué)院
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2017
【分類(lèi)號(hào)】：R589;R181.3

【參考文獻(xiàn)】

相關(guān)期刊論文 前10條

1 王嫣嫣;熊豐;張亞妮;楊彬;林琴;朱岷;曾燕;羅雁紅;宋萃;朱高慧;;重慶市7～16歲兒童青少年代謝綜合征組分的調(diào)查及影響因素的分析[J];重慶醫(yī)科大學(xué)學(xué)報(bào);2016年10期

2 丁賢彬;毛德強(qiáng);沈卓之;張春華;呂曉燕;焦艷;;重慶市城鄉(xiāng)居民代謝綜合征患病現(xiàn)狀及特征[J];中國(guó)慢性病預(yù)防與控制;2016年09期

3 張麗;李玉芳;桑曉紅;李素華;劉健;;4種代謝綜合征診斷標(biāo)準(zhǔn)在農(nóng)村維吾爾族圍絕經(jīng)期婦女中的應(yīng)用比較[J];新疆醫(yī)科大學(xué)學(xué)報(bào);2016年08期

4 邵永強(qiáng);樊麗輝;李江峰;張娜;翁曉慶;;2種診斷標(biāo)準(zhǔn)對(duì)代謝綜合征判定的差異性及其公共衛(wèi)生意義[J];中國(guó)慢性病預(yù)防與控制;2016年08期

5 王力煒;楊文彬;於濤;王雯;王濱燕;唐根富;臧桐華;秦獻(xiàn)輝;王玉;李建平;霍勇;徐希平;;連云港農(nóng)村地區(qū)高血壓人群中紅細(xì)胞分布寬度與血脂相關(guān)性研究[J];中華疾病控制雜志;2016年06期

6 趙曉南;劉國(guó)良;;肥胖——代謝綜合征的源頭[J];實(shí)用糖尿病雜志;2016年03期

7 陳江鵬;彭斌;闕萍;文小焱;胡珊;;重慶市體檢人群代謝綜合征流行狀況及其組分的結(jié)構(gòu)方程模型[J];中國(guó)衛(wèi)生統(tǒng)計(jì);2016年02期

8 李慧;王佳楠;趙瑋;白玉蓉;;不同年齡男性人群代謝綜合征的特點(diǎn)分析[J];中國(guó)循證心血管醫(yī)學(xué)雜志;2016年03期

9 鄭東鵬;;社區(qū)綜合干預(yù)高尿酸血癥對(duì)代謝綜合征各組分的影響[J];中西醫(yī)結(jié)合心腦血管病雜志;2015年14期

10 羅春華;楊紹玉;龔峰;李乾元;李雪莉;;宜昌市職業(yè)人群高尿酸血癥流行病學(xué)調(diào)查及其與代謝綜合征的相關(guān)性[J];實(shí)用醫(yī)學(xué)雜志;2015年19期

相關(guān)碩士學(xué)位論文 前1條

1 袁雪麗;深圳市代謝綜合征的流行現(xiàn)狀及其影響因素分析[D];華中科技大學(xué);2013年

，

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