本文選題：二硫化碳　切入點(diǎn)：職業(yè)暴露　出處：《環(huán)境與職業(yè)醫(yī)學(xué)》2015年01期

【摘要】：[目的]研究二硫化碳(CS2)暴露對(duì)作業(yè)工人血糖(glucose,GLU)、總膽固醇(total cholesterol,TCHO)和三酰甘油(triglyceride,TG)檢出水平的影響,并提出職業(yè)健康監(jiān)護(hù)行動(dòng)水平的建議。[方法]收集某化纖廠2004—2011年間工作場(chǎng)所CS2濃度或作業(yè)工人個(gè)體接觸CS2濃度的檢測(cè)資料,對(duì)該化纖廠3 456名接觸CS2的作業(yè)工人分別進(jìn)行GLU、TCHO和TG水平的檢查。[結(jié)果]該化纖廠作業(yè)工人接觸CS2的8 h時(shí)間加權(quán)平均濃度為0.2~41.0 mg/m3,幾何均數(shù)為2.38 mg/m3。其中1 758名作業(yè)工人接觸CS2的濃度在0.2~2.5 mg/m3之間(A組);653名作業(yè)工人接觸CS2的濃度在2.6~4.8 mg/m3之間(B組);1 045名作業(yè)工人接觸CS2的濃度在5.1~41.0 mg/m3之間(C組)。男性C濃度組高TG檢出率高于A、B兩濃度組,差異有統(tǒng)計(jì)學(xué)意義(P0.05);A、B濃度組之間差異無統(tǒng)計(jì)學(xué)意義(P0.05)。男性高GLU、高TCHO檢出率及女性高GLU、高TCHO和高TG檢出率在不同濃度組中差異均無統(tǒng)計(jì)學(xué)意義(P0.05)。各年齡段C濃度組高TG檢出率高于A、B兩濃度組;A、B濃度組間差異無統(tǒng)計(jì)學(xué)意義(P0.05)。不同濃度組間高GLU和高TCHO檢出率差異無統(tǒng)計(jì)學(xué)意義(P0.05)。男性不同累積接觸量組間高TG檢出率差異有統(tǒng)計(jì)學(xué)意義(P0.01);高GLU和高TCHO檢出率差異無統(tǒng)計(jì)學(xué)意義(P0.05)。女性不同累積接觸量組間高GLU、高TCHO和高TG檢出率差異無統(tǒng)計(jì)學(xué)意義(P0.05)。[結(jié)論]男性作業(yè)工人接觸CS2濃度5 mg/m3或累積接觸量50 mg/(m3·年)時(shí),可使高TG檢出率明顯升高。在對(duì)CS2作業(yè)工人進(jìn)行職業(yè)健康監(jiān)護(hù)時(shí),宜執(zhí)行CS2時(shí)間加權(quán)平均濃度為2.5 mg/m3(職業(yè)接觸限值的1/2)的行動(dòng)水平,并加強(qiáng)對(duì)累積接觸量50 mg/(m3·年)的作業(yè)工人的健康檢查。
[Abstract]:[objective] to study the effects of carbon disulfide (CS2) exposure on the detection of blood glucose, total cholesterol total cholesterol (TCHO) and triglyceride-triglyceride-triglyceride-triglyceride-triglyceride (TGG) levels in exposed workers. Suggestions on the action level of occupational health monitoring were put forward. [methods] data of CS2 concentration in the workplace or exposure to CS2 concentration of individual workers were collected from 2004 to 2011 in a chemical fiber factory. The GLUTCHO and TG levels of 3 456 workers exposed to CS2 in the chemical fiber factory were examined respectively. [results] the weighted average concentration of 8 hours of exposure to CS2 was 0.2mg / m3 and the geometric mean was 2.38 mg / m3.The geometric mean value was 2.38 mg / m3.Of the 1,758 workers exposed to CS2, the weighted average concentration for 8 hours was 0.2mg / m3.The geometric mean value was 2.38mgm3.758 of them were exposed to CS2. The exposure concentration of CS2 to CS2 was between 0.22 mg/m3 and 2.5 mg/m3 in group A 653 workers exposed to CS2 in the range of 2.6 mg/m3 to 4.8 mg/m3. The concentration of CS2 in group B was between 5.1g and 41.0 mg/m3. The detection rate of high TG in male group C was higher than that in group A and B, and that in group C was higher than that in group A and B. There was no significant difference between the two groups. There was no significant difference between the two groups. There was no significant difference in the detection rate of high GLU, high TCHO and high GLU in women. There was no significant difference in the detection rates of high TCHO and high TG in different concentration groups. There was no significant difference in the detection rate of high TG and high TCHO between the two concentration groups. There was no significant difference in the detection rate of high GLU and high TCHO among different concentration groups. There was statistical difference in the detection rate of high TG among different cumulative exposure groups of men. There was no significant difference in the detection rate between high GLU and high TCHO. There was no significant difference in the detection rate of high GLU, high TCHO and high TG among women with different cumulative exposure. [conclusion] male workers exposed to 5 mg/m3 or accumulated CS2 concentration. When the exposure is 50 mg/(m3 years, In occupational health monitoring of workers exposed to CS2, the weighted average concentration of CS2 time is 2.5 mg / m3 (1 / 2 of occupational exposure limit). The health examination of workers with cumulative exposure of 50 mg/(m3 was also strengthened.
【作者單位】： 河南省職業(yè)病防治研究院;中國(guó)疾病預(yù)防控制中心職業(yè)衛(wèi)生與中毒控制所;
【基金】：衛(wèi)生部衛(wèi)生行業(yè)科研專項(xiàng)項(xiàng)目(編號(hào):200902006)
【分類號(hào)】：R131
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本文編號(hào)：1666754