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Understanding super-enhancers

發(fā)布時(shí)間:2017-07-04 08:16

  本文關(guān)鍵詞:Understanding super-enhancers


  更多相關(guān)文章: enhancer proximal dense activate SUPER interests intense promoter sequencing embryonic


【摘要】:正Super-enhancers are defined as cluster of enhancers with dense TF binding,which can activate proximal cell-identity gene expression.Here we review the identification,functional significance of super-enhancers,and their relationships with cancer.With the current intense interests in super-enhancers,more super-enhancers will be defined and
【作者單位】: Key
【關(guān)鍵詞】enhancer;proximal;dense;activate;SUPER;interests;intense;promoter;sequencing;embryonic;
【基金】:supported by the National Natural Science Foundation of China(31210103916;91329302 and 91519330) the Progress on CAS Strategic Priority Research Program(XDA01010303) the Instrument Developing Project of the Chinese Academy of Sciences(YZ201243) the National Basic Research Program of China(2015CB964803 and 2011CB504206)to Jing-Dong J.Han
【分類號(hào)】:R961
【正文快照】: Super-enhancers are defined as cluster of enhancers withdense TF binding,which can activate proximal cell-identitygene expression.Here we review the identification,func-tional significance of super-enhancers,and their relation-ships with cancer.With the

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