<正>0引言結外NK/T細胞淋巴瘤是一種原發(fā)于鼻腔的正常淋巴細胞異常激活和（或）異常分化的惡性腫瘤,其中鼻腔是常見部位,也可發(fā)生在皮膚、胃腸道、肺、心臟等部位[1-3]。結外NK/T細胞淋巴瘤易并發(fā)嗜血細胞綜合征（hemophagocytic syndrome,HPS）,但合并傳染性單核細胞增多癥（infectious mononucleosis,IM）的概率較低,國內(nèi)外未見報 

【文章來源】：腫瘤防治研究. 2015,42(09)北大核心

【文章頁數(shù)】：3 頁

【部分圖文】：

鼻腔NK/T細胞淋巴瘤治療后并發(fā)傳染性單核細胞增多癥患者鼻咽CT影像學表現(xiàn)Figure1NasopharyngealCTimagingofpatientwithnasal

感染是這類腫瘤的病因。本例患者發(fā)病時也具有EBV含量增高，給予DICE+L-asp的方案治療后EBV含量下降，PET-CT提示完全緩圖1鼻腔NK/T細胞淋巴瘤治療后并發(fā)傳染性單核細胞增多癥患者鼻咽CT影像學表現(xiàn)Figure1NasopharyngealCTimagingofpatientwithnasalNK/TcelllymphomacomplicatinginfectiousmononucleosisafterchemotherapyA:Theconventionaldyeingoflymphnodelesions(HE×200);B:ThenegativeexpressionofCD20(IHC×200);C:ThepositiveexpressionofKi-67(IHC×200);D:ThepositiveexpressionofCD56(IHC×200)圖2鼻腔NK/T細胞淋巴瘤治療后并發(fā)傳染性單核細胞增多癥患者病理常規(guī)及免疫組織化學Figure2PathologicalandimmunohistochemicalstainingofthepatientwithnasalNK/Tcelllymphomacomplicatinginfectiousmononucleosisafterchemotherapy圖3鼻腔NK/T細胞淋巴瘤治療后并發(fā)傳染性單核細胞增多癥患者鼻咽18F-FDGPET-CT影像學表現(xiàn)Figure3Nasopharyngeal18F-FDGPET-CTimagingofpatientwithnasalNK/TcelllymphomacomplicatinginfectiousmononucleosisafterchemotherapyA,B:Differentviewsofthesamecells圖4鼻腔NK/T細胞淋巴瘤治療后并發(fā)傳染性單核細胞增多癥患者外周血細胞形態(tài)（瑞士-吉姆薩染色×1000）Figure4PeripheralbloodcellmorphologyofpatientwithnasalNK/Tcelllymphomacomplicatinginfectiousmononucleosisafterchemotherapy(Switzerland-Giemsastaining×1000)A,B:Differentviewsofthesamecells圖5鼻腔NK/T細胞淋巴瘤治療后并發(fā)傳染性單核細胞增多癥患者骨髓細胞形態(tài)（瑞士吉姆薩染色×1000）Figure5BonemarrowcellsmorphologyofpatientwithnasalNK/Tcelllymphomac

gingofpatientwithnasalNK/TcelllymphomacomplicatinginfectiousmononucleosisafterchemotherapyA:Theconventionaldyeingoflymphnodelesions(HE×200);B:ThenegativeexpressionofCD20(IHC×200);C:ThepositiveexpressionofKi-67(IHC×200);D:ThepositiveexpressionofCD56(IHC×200)圖2鼻腔NK/T細胞淋巴瘤治療后并發(fā)傳染性單核細胞增多癥患者病理常規(guī)及免疫組織化學Figure2PathologicalandimmunohistochemicalstainingofthepatientwithnasalNK/Tcelllymphomacomplicatinginfectiousmononucleosisafterchemotherapy圖3鼻腔NK/T細胞淋巴瘤治療后并發(fā)傳染性單核細胞增多癥患者鼻咽18F-FDGPET-CT影像學表現(xiàn)Figure3Nasopharyngeal18F-FDGPET-CTimagingofpatientwithnasalNK/TcelllymphomacomplicatinginfectiousmononucleosisafterchemotherapyA,B:Differentviewsofthesamecells圖4鼻腔NK/T細胞淋巴瘤治療后并發(fā)傳染性單核細胞增多癥患者外周血細胞形態(tài)（瑞士-吉姆薩染色×1000）Figure4PeripheralbloodcellmorphologyofpatientwithnasalNK/Tcelllymphomacomplicatinginfectiousmononucleosisafterchemotherapy(Switzerland-Giemsastaining×1000)A,B:Differentviewsofthesamecells圖5鼻腔NK/T細胞淋巴瘤治療后并發(fā)傳染性單核細胞增多癥患者骨髓細胞形態(tài)（瑞士吉姆薩染色×1000）Figure5BonemarrowcellsmorphologyofpatientwithnasalNK/Tcelllymphomacomplicatinginfectiousmononucleosisafterchemotherapy(Switzerland-Giemsastaining×1000)

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