【摘要】：目的:探索兒童分泌性中耳炎與變態(tài)反應(yīng)的關(guān)系。方法:將42例分泌性中耳炎患兒隨機(jī)分為實(shí)驗(yàn)組和對(duì)照組各21例,兩組患兒給予糖皮質(zhì)激素霧化吸入,仙璐貝滴劑和二、三代頭孢口服;在此基礎(chǔ)上實(shí)驗(yàn)組加用地氯雷他定口服,兩組均治療4周。通過患者血清免疫球蛋白含量檢測(cè),觀察抗變態(tài)反應(yīng)治療對(duì)治療兒童分泌性中耳炎的療效。結(jié)果:治療后3個(gè)月隨訪,實(shí)驗(yàn)組痊愈14例,有效7例;對(duì)照組痊愈9例,有效8例,無效4例,兩組治療有效率差異有統(tǒng)計(jì)學(xué)意義(P0.05);實(shí)驗(yàn)組血清Ig E水平明顯低于對(duì)照組(P0.05)。結(jié)論:對(duì)于內(nèi)分泌性中耳炎患兒進(jìn)行抗變態(tài)反應(yīng)治療效果顯著,兒童分泌性中耳炎與變態(tài)反應(yīng)的關(guān)系密切。
[Abstract]:Objective: to explore the relationship between secretory otitis media and allergy in children. Methods: 42 children with secretory otitis media were randomly divided into experimental group (n = 21) and control group (n = 21). The two groups were treated with glucocorticoid atomization inhalation, Xianlubei drops and second and third generation cephalosporins, on the basis of which the experimental group was treated with loratadine for 4 weeks. The effect of antiallergic therapy on secretory otitis media in children was observed by detecting the content of serum immunoglobulin. Results: three months after treatment, 14 cases were cured and 7 cases were effective in the experimental group, 9 cases in the control group were cured, 8 cases were effective and 4 cases were ineffective, the difference of the effective rate between the two groups was statistically significant (P 0.05), and the level of serum Ig E in the experimental group was significantly lower than that in the control group (P 0.05). Conclusion: antiallergic therapy is effective in children with endocrine otitis media, and the relationship between secretory otitis media and allergy is close.
【作者單位】： 河北省唐山市婦幼保健院耳鼻咽喉科;唐山市婦幼保健院檢驗(yàn)科;
【分類號(hào)】：R764.21

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