【摘要】：目的 研究海南地區(qū)白內(nèi)障患者的眼生物學(xué)指標(biāo)特征;建立白內(nèi)障患者眼生物學(xué)指標(biāo)的多指標(biāo)臨床診治參考值范圍。 方法 研究對(duì)象為2009年至2010年在海南地區(qū)的白內(nèi)障患者,共8849例8849眼。研究項(xiàng)目:性別、年齡、檢查眼別、裸眼視力和眼壓、眼生物學(xué)指標(biāo)(前房深度、晶狀體厚度、玻璃體腔深度、眼軸長(zhǎng)度、水平及垂直角膜曲率、角膜內(nèi)皮細(xì)胞計(jì)數(shù)、中央角膜厚度)。所有數(shù)據(jù)輸入計(jì)算機(jī),應(yīng)用SPSS15.0統(tǒng)計(jì)學(xué)軟件進(jìn)行統(tǒng)計(jì)分析。 結(jié)果 1、白內(nèi)障患者年齡為71.2±10.0歲;女性白內(nèi)障患者年齡(71.4±9.6歲)較男性患者(70.8±10.7歲)大(t test, P=0.017)。 2、白內(nèi)障患者眼生物學(xué)指標(biāo):角膜內(nèi)皮細(xì)胞計(jì)數(shù)(2550.7±375.0個(gè)/mm2);中央角膜厚度(501.12±34.95μm);水平角膜曲率(44.21±1.85D);垂直角膜曲率(44.77±1.77D);前房深度(3.205±0.431mm);晶狀體厚度(4.300±0.629mm);玻璃體腔深度(15.878±1.231mm);眼軸長(zhǎng)度(23.380±1.229mm)。 3、50歲及以上白內(nèi)障患者男性前房深度、晶狀體厚度、玻璃體腔深度、眼軸長(zhǎng)度均高于女性;男性中央角膜厚度較女性厚;女性水平及垂直角膜曲率大于男性;性別間角膜內(nèi)皮細(xì)胞計(jì)數(shù)相近。 4、50歲及以上白內(nèi)障患者眼生物學(xué)指標(biāo)的95%多指標(biāo)臨床診治參考值范圍(多指標(biāo)百分位數(shù)法確定):前房深度(男:1.88～4.21mm,女:1.87～4.13mm),晶狀體厚度(男:2.26～6.36mm,女:2.58～6.19mm),玻璃體腔深度(男:13.90～21.28mm,女:13.45～22.27mm),眼軸長(zhǎng)度(男:21.50～29.32mm,女:21.11～29.78mm),角膜內(nèi)皮細(xì)胞計(jì)數(shù)(男≥1694個(gè)/mm2,女≥1611個(gè)/mm2),中央角膜厚度(男:421～600μm,女:411～588μm),水平角膜曲率(男:38.49～47.88D,女:39.25～49.25D),垂直角膜曲率(男:39.79～49.25D,女:40.87～49.87D)。 結(jié)論 首次對(duì)大樣本白內(nèi)障患者眼生物學(xué)指標(biāo)進(jìn)行研究分析,得出詳實(shí)的測(cè)量數(shù)據(jù),并首次構(gòu)建了50歲及以上白內(nèi)障患者眼生物學(xué)指標(biāo)的95%多指標(biāo)臨床診治參考值范圍,填補(bǔ)了該領(lǐng)域的空白,為白內(nèi)障患者診治提供參考依據(jù)。
[Abstract]:Objective to study the characteristics of eye biological indexes of cataract patients in Hainan area and to establish the reference range of multi-index clinical diagnosis and treatment of eye biological indexes of cataract patients. Methods from 2009 to 2010, 8849 patients (8849 eyes) were enrolled in this study. Study items: sex, age, examination of eye, uncorrected visual acuity and intraocular pressure, eye biological indexes (anterior chamber depth, lens thickness, vitreous cavity depth, axial length, horizontal and vertical corneal curvature, corneal endothelial cell count, Central corneal thickness). All the data were input into the computer and analyzed by SPSS15.0 statistical software. Results 1 the age of cataract patients was 71.2 鹵10.0 years old, and the age of female cataract patients (71.4 鹵9.6 years old) was larger than that of male patients (70.8 鹵10.7 years old). 2. The biological parameters of cataract patients were as follows: corneal endothelial cell count (2550.7 鹵375.0 / mm2), central corneal thickness (501.12鹵 34.95 渭 m), horizontal corneal curvature (44.21D 鹵1.85D), vertical corneal curvature (44.77鹵 1.77D), corneal thickness (501.12鹵 34.95mm), horizontal corneal curvature (44.21D), vertical corneal curvature (44.77D). Anterior chamber depth (3.205 鹵0.431 mm); lens thickness 4.300 鹵0.629 mm); vitreous cavity depth (15.878 鹵1.231 mm); eye axis length 23.380 鹵1.229 mm).) 3The depth of anterior chamber, lens thickness, vitreous cavity depth and axial length of eyes in men with cataract aged 50 and over were higher than those in women, the thickness of central cornea in males was thicker than that in females, and the horizontal and vertical corneal curvature in females was higher than that in males. The number of corneal endothelial cells was similar between sexes. 4. the range of 95% reference value of clinical diagnosis and treatment of eye biological indexes in patients aged 50 years and over (determined by multi-index percentile method): anterior chamber depth (male: 1.88 鈮，

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