【摘要】：目的探討屈光參差性弱視雙眼間的波前像差差異以及臨床特點(diǎn)。方法選取53例屈光參差性弱視患者,年齡9~40歲,其中男31例,女22例,納入本橫斷面研究。所有患者均接受Wave Scan溲波前像差檢查,弱視眼與對(duì)側(cè)眼之間的波前像差差異采用配對(duì)t檢驗(yàn);波前像差參數(shù)值、等效離焦度、最佳矯正視力,以及年齡之間的關(guān)系采用相關(guān)分析。然后將中度弱視患者按照年齡分為成年弱視組和兒童弱視組,分析這兩組的臨床特點(diǎn)。結(jié)果經(jīng)配對(duì)t檢驗(yàn)顯示,53例患者的弱視眼與對(duì)側(cè)眼在最佳矯正視力、等效離焦度、總像差、總高階像差、三葉草像差、三階像差均方根值等指標(biāo)上差異均有統(tǒng)計(jì)學(xué)意義(均為P0.05)。成年弱視組與兒童弱視組內(nèi)均未發(fā)現(xiàn)年齡與高階像差參數(shù)之間存在相關(guān)性。成年弱視組弱視眼與對(duì)側(cè)眼之間在總像差(P=0.000)、三葉草像差(P=0.047)和三階像差均方根值(P=0.032)上差異均有統(tǒng)計(jì)學(xué)意義(均為P0.05);兒童弱視組弱視眼與對(duì)側(cè)眼之間在總像差(P=0.000)、球差(P=0.008)和四階像差均方根值(P=0.032)上差異均有統(tǒng)計(jì)學(xué)意義(均為P0.05)。兩個(gè)年齡組內(nèi)的相關(guān)回歸分析顯示,在成年弱視組,等效離焦度與總像差有相關(guān)性(P0.01),最佳矯正視力與總像差、球差均有相關(guān)性(均為P0.05);且等效離焦度與總像差的回歸方程為y=3.343+0.942x(F=40.830、P=0.000、R2=0.671),最佳矯正視力與總像差的回歸方程為y=0.321+0.017x(F=5.058、P=0.036、R2=0.202)。在兒童弱視組,等效離焦度與總像差、總高階像差均有相關(guān)性(均為P0.05),最佳矯正視力與五階像差均方根值存在相關(guān)性(P0.01);等效離焦度與總像差的回歸方程為y=1.529+1.176x(F=17.090、P=0.001、R2=0.501),最佳矯正視力與五階像差均方根值的回歸方程為y=0.006+0.143x(F=10.851、P=0.004、R2=0.390)。結(jié)論除最佳矯正視力、等效離焦度、總像差之外,屈光參差性弱視患者雙眼間的高階像差存在顯著差異;對(duì)于中度弱視患者,雙眼間高階像差差異在成人與兒童表現(xiàn)不同。
[Abstract]:Objective to investigate the wavefront aberrations and clinical characteristics of anisometropic amblyopia. Methods 53 patients with anisometropic amblyopia, aged 9 to 40, including 31 males and 22 females, were included in this cross-sectional study. All patients were examined by Wave Scan wavefront aberration. The difference of wavefront aberration between amblyopia and contralateral eyes was tested by paired t-test. Correlation analysis was used for wavefront aberration parameters, equivalent defocus, best corrected visual acuity, and age. Then the patients with moderate amblyopia were divided into adult amblyopia group and children amblyopia group according to their age, and the clinical characteristics of the two groups were analyzed. Results the paired t test showed that the amblyopia and contralateral eyes of 53 patients had the best corrected visual acuity, the equivalent defocus, the total aberration, the total high order aberration, the clover aberration, the best corrected visual acuity, the equivalent defocus, the total aberration, the total high order aberration and the clover aberration. There were significant differences in root mean square values of third order aberrations (all P0.05). There was no correlation between age and high-order aberrations in adult amblyopia group and children amblyopia group. In adult amblyopia group, there were significant differences between amblyopia eyes and contralateral eyes in total aberrations (P < 0. 000), clover aberrations (P < 0. 047) and root mean square values of third-order aberrations (P < 0. 05). There were significant differences between amblyopia eyes and contralateral eyes in total aberration (P < 0. 000), spherical aberration (P < 0. 008) and root mean square value of fourth-order aberration (P < 0. 032) in children amblyopia group (P 0. 05). The correlation regression analysis between the two age groups showed that in adult amblyopia group, the equivalent defocus was correlated with the total aberration (P0.01), and the best corrected visual acuity was correlated with the total aberration and spherical aberration (all P0.05). The regression equation between the equivalent defocus and the total aberration was y = 3.343 0.942 x (F = 40.830, P = 0.000, R _ 2 = 0.671), and the regression equation between the best corrected visual acuity and the total aberration was y = 0.321 0.017 x (F = 5.058, P = 0.036, R _ 2 = 0.202). In the amblyopia group, the equivalent defocus was correlated with the total aberration and the total high-order aberration (all P0.05), and the best corrected visual acuity was correlated with the root mean square value of the fifth-order aberration (P0.01). The regression equation between the equivalent defocus and the total aberration was y = 1.529 1.176x (F = 17.090, P = 0.0001, R2 = 0.501). The regression equation between the best corrected visual acuity and the root mean square value of the fifth-order aberration was y = 0.006 0.143x (F = 10.851, P = 0.004, R _ 2 = 0.390). Conclusion there are significant differences in higher order aberrations between the eyes of anisometropic amblyopia patients except for the best corrected visual acuity, equivalent defocus and total aberrations, and for moderate amblyopic patients, the difference of higher order aberrations between the eyes of adults and children is different.
【作者單位】： 廣西壯族自治區(qū)人民醫(yī)院視光科廣西視光中心;
【基金】：廣西壯族自治區(qū)衛(wèi)生廳資助項(xiàng)目(編號(hào):桂衛(wèi)Z2013336) 廣西壯族自治區(qū)人民醫(yī)院青年基金項(xiàng)目~~
【分類號(hào)】：R777.44

【參考文獻(xiàn)】

相關(guān)期刊論文 前6條

1 于風(fēng)娟;宋海燕;劉隴黔;鄧應(yīng)平;王琳;;高階像差在屈光性弱視中的評(píng)價(jià)分析[J];四川大學(xué)學(xué)報(bào)(醫(yī)學(xué)版);2009年02期

2 李謙;楊旭波;劉隴黔;;弱視患者自適應(yīng)光學(xué)系統(tǒng)矯正高階像差前后視覺(jué)行為變化的研究[J];四川大學(xué)學(xué)報(bào)(醫(yī)學(xué)版);2014年03期

3 邱煦;譚琦;廖孟;劉隴黔;;高階像差在遠(yuǎn)視兒童屈光參差性弱視中的評(píng)價(jià)[J];生物醫(yī)學(xué)工程學(xué)雜志;2011年06期

4 趙武校;劉偉民;林恩韋;楊佳;王英;羅武強(qiáng);;近視性屈光參差的波前像差研究[J];眼科新進(jìn)展;2010年12期

5 劉向玲,張子英,胡俊喜,周玉蘭,李高粱;綜合療法治療小兒微小度數(shù)斜視性弱視[J];新鄉(xiāng)醫(yī)學(xué)院學(xué)報(bào);2005年04期

6 雷光明;張新萍;李波;;綜合治療兒童弱視30例療效觀察[J];新鄉(xiāng)醫(yī)學(xué)院學(xué)報(bào);2006年01期

【共引文獻(xiàn)】

相關(guān)期刊論文 前10條

1 許江濤;郭智一;鄧敏;鐘江濤;夏紅玉;肖亦爽;;兒童微小內(nèi)斜視的治療及其療效觀察[J];國(guó)際眼科雜志;2009年07期

2 曾容斌;;驗(yàn)光配鏡加遮蓋法治療兒童屈光性弱視療效觀察[J];華夏醫(yī)學(xué);2008年06期

3 朱海豐;張另坦;方志良;;基于不同人眼模型的非球面人工晶體光學(xué)性能研究[J];光電子.激光;2014年09期

4 趙曉彬;馬清敏;賈志e，

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