發(fā)布時間：2019-03-09 08:45

【摘要】：目的：回顧性分析等離子射頻消融手術(shù)對早期聲門型喉癌的治療效果。 方法：2009年11月—2014年1月，在上海交通大學附屬上海市第六人民醫(yī)院耳鼻咽喉頭頸外科收治的早期聲門型喉癌患者53例。其中行等離子射頻消融術(shù)患者15例，行CO2激光切除術(shù)患者13例，行部分喉切除術(shù)患者25例。所有患者術(shù)后門診電子喉鏡及電話隨訪。應(yīng)用SPSS18.0統(tǒng)計分析比較三種手術(shù)方案的臨床數(shù)據(jù)。 結(jié)果：早期聲門型喉癌患者經(jīng)等離子射頻治療后平均住院天數(shù)為（8.20±2.76）天， CO2激光治療后為（9.23±4.02）天（P=0.431），，部分喉切除治療后為（19.68±10.14）天（P=0.000及0.001）;等離子射頻治療組平均手術(shù)時間為（0.92±0.65）h，CO2激光治療組為（0.72±0.34）h（P=0.320），而部分喉切除治療為（2.61±0.92）h（P=0.000及0.000）;CO2激光治療組住院費用優(yōu)于等離子射頻治療組（P=0.043），兩者明顯優(yōu)于部分喉切除組；等離子射頻組及CO2激光組術(shù)中出血明顯優(yōu)于部分喉切除組；三組術(shù)后復(fù)發(fā)率無明顯統(tǒng)計學差異。 結(jié)論：等離子射頻消融治療早期聲門型喉癌的術(shù)后復(fù)發(fā)率，相對于CO2激光治療和部分喉切除治療無明顯差異；較部分喉切除手術(shù)具有手術(shù)時間短、創(chuàng)傷小、無需氣管切開、術(shù)后并發(fā)癥少、術(shù)后生活質(zhì)量高等優(yōu)勢。
[Abstract]:Objective: to retrospectively analyze the therapeutic effect of plasma radiofrequency ablation for early glottic carcinoma. Methods: from November 2009 to January 2014, 53 patients with early glottic laryngeal carcinoma were treated in the department of otorhinolaryngology, head and neck surgery, Shanghai sixth people's Hospital affiliated to Shanghai Jiaotong University. Plasma radiofrequency ablation was performed in 15 cases, CO2 laser in 13 cases, and partial laryngectomy in 25 cases. All patients were followed up by electronic laryngoscope and telephone. SPSS18.0 was used to analyze and compare the clinical data of three surgical schemes. Results: the average hospitalization days of patients with early glottic carcinoma and CO2 laser were (8.20 鹵2.76) days and (9.23 鹵4.02) days (P = 0.431), and the mean hospitalization days after plasma radio frequency treatment were (8.20 鹵2.76) days and (9.23 鹵4.02) days, respectively. After partial laryngectomy, it was (19.68 鹵10.14) days (P < 0.0000 and 0.001). The mean operating time was (0.92 鹵0.65) h in the plasma radio frequency group, (0.72 鹵0.34) h (/ P / L) in the CO _ 2 laser group, and (2.61 鹵0.92) h (/ L) in the partial laryngectomy group (P < 0.05 and 0.000). The hospitalization cost of CO2 laser treatment group was better than that of plasma radio frequency treatment group (P0. 043), and both of them were significantly better than partial laryngectomy group. The bleeding in plasma radio frequency group and CO2 laser group was significantly better than that in partial laryngectomy group, and there was no significant difference in postoperative recurrence rate among the three groups. Conclusion: the recurrence rate of early glottic carcinoma treated with plasma radiofrequency ablation has no significant difference compared with CO2 laser and partial laryngectomy. Compared with partial laryngectomy, it has the advantages of shorter operation time, less trauma, no tracheotomy, less complications and higher quality of life after operation.
【學位授予單位】：上海交通大學
【學位級別】：碩士
【學位授予年份】：2014
【分類號】：R739.65

【參考文獻】

相關(guān)期刊論文 前4條

1 吳昆e

本文編號：2437286