發(fā)布時間：2018-12-13 16:10

【摘要】：目的:探討阻塞性睡眠呼吸暫停綜合征患者(OSAS)夜間睡眠對日間嗜睡的影響。 方法:在我們的研究中依次納入AHI5次/小時的OSAS患者182例,依據(jù)多次日間睡眠潛伏期測試(MSLT)和Epworth嗜睡量表(ESS)資料進(jìn)行日間嗜睡分組:①日間嗜睡組(EDS組,n=32):ESS10分,MSLT5分鐘;②非日間嗜睡組(No-EDS組,n=48):ESS≤10分,MSLT10分鐘。 結(jié)果:與No-EDS患者比較,EDS患者有以下特征:1)AHI更大,血氧飽和度95%的時間更長,在REM及NREM睡眠期平均血氧飽和度,整夜最低血氧和平均血氧飽和度更低;2)睡眠潛伏期和REM睡眠潛伏期更短,總的睡眠時間更長和睡眠效率更高;3)微覺醒指數(shù)更高,1期睡眠持續(xù)時間更長,慢波睡眠比例降低。此外通過逐步logistic回歸分析發(fā)現(xiàn)只有夜間睡眠的微覺醒指數(shù)、血氧飽和度95%的時間、REM睡眠潛伏期是日間嗜睡的獨(dú)立預(yù)測因子。 結(jié)論:研究結(jié)果表明有日間嗜睡的OSAS患者夜間睡眠具有以下特征:1)嚴(yán)重的呼吸暫停/低通氣和低氧血癥,2)片段化睡眠,3)睡眠質(zhì)量差和睡眠壓力高。
[Abstract]:Objective: to investigate the effect of (OSAS) sleep on daytime sleepiness in patients with obstructive sleep apnea syndrome (OSAS). Methods: one hundred and eighty-two OSAS patients with AHI5 / hour were included in our study. According to (MSLT) and (ESS) data of multiple daytime sleep latency test, daytime sleepiness was divided into 1 day sleepiness group (EDS group), 1 day somnolence group (EDS group), 1 day sleepiness group (EDS group), and 1 day sleepiness group (EDS group). ESS10 score, MSLT5 minute; 2 Non-daytime sleepiness group (No-EDS group, n = 48): ESS 鈮，

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