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兒童腺樣體局部菌群與分泌性中耳炎的關(guān)系

發(fā)布時(shí)間:2018-11-19 22:07
【摘要】:目的:探究腺樣體肥大患兒當(dāng)中局部菌群情況與慢性分泌性中耳炎(cMOE)發(fā)病的關(guān)系。方法:對(duì)計(jì)劃行腺樣體切除術(shù)的患兒,切除前于鼻內(nèi)鏡下腺樣體表面、深部取分泌物行細(xì)菌培養(yǎng),對(duì)培養(yǎng)結(jié)果進(jìn)行分類(lèi)統(tǒng)計(jì)、分析。結(jié)果:在腺樣體表面和深部取樣中,發(fā)現(xiàn)條件致病菌(肺炎鏈球菌、流感嗜血桿菌和卡他莫拉菌)的出現(xiàn)率為5%~15%,在無(wú)慢性分泌性中耳炎(Ⅰ組)和cMOE(Ⅱ組)之間差異無(wú)顯著性;在腺樣體表面和深部化膿性鏈球菌陽(yáng)性率(P=0.036)、腺樣體深部普雷沃菌陽(yáng)性率(P=0.046)差異有統(tǒng)計(jì)學(xué)意義。結(jié)論:在兒童腺樣體肥大合并慢性分泌性中耳炎患者當(dāng)中,根據(jù)研究結(jié)果我們傳統(tǒng)認(rèn)為的部分致病菌(肺炎鏈球菌、流感嗜血桿菌和卡他莫拉菌)在cMOE致病因素中沒(méi)有想象的那么重要,反而部分細(xì)菌表現(xiàn)出來(lái)的抑制機(jī)制在cMOE發(fā)病有一定作用。因此,我們有理由認(rèn)為細(xì)菌間的相互干擾、抑制可能是cMOE發(fā)病的一個(gè)重要因素。
[Abstract]:Objective: to investigate the relationship between local flora and (cMOE) in children with adenoid hypertrophy. Methods: the children who planned adenoidectomy were cultured on the surface of adenoid under nasal endoscope and the secretions were taken from the deep part of the nasal endoscope. The results of culture were classified and analyzed. Results: the incidence of opportunistic pathogens (Streptococcus pneumoniae, Haemophilus influenzae, and Morrah) was found in the surface and deep samples of adenoids. There was no significant difference between chronic secretory otitis media (group 鈪,

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