【摘要】：近十余年來,我國原發(fā)性開角型青光眼(以下簡稱開青)患病率逐年上升,由0.29%上升到2.6%,一躍成為最重要的不可逆性致盲眼病。由于對開青眼壓升高及視神經(jīng)損害的機制認(rèn)識不清,缺乏可行的篩查及有效的干預(yù)技術(shù),其致盲率遠(yuǎn)高于發(fā)達國家8%的平均水平。王寧利教授所領(lǐng)導(dǎo)的項目組從回答開青眼壓升高和視神經(jīng)損害的關(guān)鍵科學(xué)問題入手,以解決開青篩查和監(jiān)測的關(guān)鍵技術(shù)和設(shè)備為突破口,在闡明開青發(fā)病機制的基礎(chǔ)上建立了基于機制的新分類體系,并在新理論、新分類基礎(chǔ)上創(chuàng)建了新的開青篩查、診斷、監(jiān)測和治療技術(shù),在全國范圍內(nèi)推廣應(yīng)用。覆蓋人群1.2億,實際受益患者320萬人,減少因開青致盲約32萬人,開青致盲率由15%下降到5%,減少開青致殘約64萬人,致殘率由30%下降到15%。
[Abstract]:In recent ten years, the prevalence rate of primary open-angle glaucoma (hereinafter referred to as Kaiqing) has increased year by year, from 0.29% to 2.6%, which has become the most important irreversible blindness. The blindness rate was much higher than the average of 8% in developed countries due to the lack of clear understanding of the mechanism of elevated intraocular pressure and optic nerve damage and the lack of feasible screening and effective intervention techniques. The project team led by Professor Wang Ningli began by answering the key scientific questions of elevated intraocular pressure and optic nerve damage, taking the key technology and equipment for screening and monitoring Kaiqing as a breakthrough. A new classification system based on mechanism was established on the basis of expounding the pathogenesis of Kaiqing disease, and a new screening, diagnosis, monitoring and treatment technology was established on the basis of new theory and new classification, which was popularized and applied in the whole country. 120 million people were covered, 3.2 million patients were actually benefited, about 320000 people were reduced to blindness caused by opening green, the rate of blindness caused by youth was reduced from 15% to 5, and the disability rate was reduced from 30% to 15%, and 640000 cases were reduced from 30% to 15%.
【作者單位】： 首都醫(yī)科大學(xué)附屬北京同仁醫(yī)院北京市眼科研究所;
【基金】：國家自然科學(xué)基金(81271005,81300767)~~
【分類號】：R775.2

【參考文獻】

相關(guān)期刊論文 前4條

1 王懷洲;曹奕雯;趙博文;洪潔;付晶;王寧利;;Schlemm管成形術(shù)治療成年人開角型青光眼手術(shù)效果一年隨訪[J];眼科;2014年01期

2 陳霄雅;王懷洲;王寧利;;微創(chuàng)青光眼手術(shù)新進展[J];眼科;2014年01期

3 王懷洲;洪潔;趙博文;桑景葒;王寧利;;Ex-PRESS房水引流物植入術(shù)聯(lián)合抗新生血管藥物治療新生血管性青光眼的一年效果[J];眼科;2014年04期

4 王寧利;王懷洲;;1.8mm切口青光眼白內(nèi)障聯(lián)合術(shù)手術(shù)簡介[J];中華眼科醫(yī)學(xué)雜志(電子版);2011年01期

【共引文獻】

相關(guān)期刊論文 前10條

1 Hui Chen;Ying-Chuan Fan;Qi-Hong He;Xiao-Yun Wu;Min Wei;June E.Eichner;Bradley K.Farris;P.Lloyd Hildebrand;Chun-Tao Lei;Shu-Hua Wu;Jing-Yun Yang;;Changed trends of major causes of visual impairment in Sichuan,China from 1987 to 2006[J];International Journal of Ophthalmology(English Edition);2014年01期

2 博文;孫光華;張美玲;彭志理;姜麗;劉艷s，

本文編號：2338717