【摘要】：摘要 目的：檢測(cè)幽門螺桿菌(Helipcobacter pylori, HP)在學(xué)齡前兒童單純肥大的扁桃體組織中的感染情況,探討HP在扁桃體肥大中的作用及其臨床意義。 方法：收集單純扁桃體肥大患兒手術(shù)摘除的扁桃體組織標(biāo)本80例,同時(shí)收集同期住院手術(shù)治療的兒童慢性扁桃體炎的扁桃體標(biāo)本40例。采用免疫組化技術(shù)定性檢測(cè)幽門螺桿菌在肥大扁桃體中的感染情況,對(duì)各組幽門螺桿菌感染情況進(jìn)行對(duì)比研究。 結(jié)果：80例單純肥大扁桃體中44例有HP表達(dá),感染陽性率為55.0%；而在慢性扁桃體炎組40例中,有7例HP為陽性,感染率為17.5%。HP在單純扁桃體肥大組的表達(dá)陽性率顯著高于對(duì)照組,差異具有統(tǒng)計(jì)學(xué)意義(P0.05)。其中男性患兒HP感染率為55.7%,女性患兒為53.6%,兩者差異無統(tǒng)計(jì)學(xué)意義(P＞0.05)。比較Ⅰ、Ⅱ、Ⅲ度肥大的扁桃體組織中HP感染率發(fā)現(xiàn)：Ⅱ度扁桃體肥大者HP感染率明顯高于Ⅰ度扁桃體肥大組(P＜0.05),Ⅲ度肥大組HP明顯高于其他兩組(P＜0.05)。伴發(fā)分泌性中耳炎的肥大扁桃體組織HP感染率較單純扁桃體肥大者高,且顯著高于僅伴有腺樣體肥大的患兒(P0.05)。 結(jié)論：HP感染可能在學(xué)齡前兒童單純扁桃體肥大的發(fā)病機(jī)制中起著一定的作用,并影響分泌性中耳炎的發(fā)生與發(fā)展。
[Abstract]:Objective: to detect the infection of Helicobacter pylori (Helipcobacter pylori, HP) in simple hypertrophic tonsils of preschool children and to explore the role of HP in tonsil hypertrophy and its clinical significance. Methods: 80 cases of tonsillectomy and 40 cases of chronic tonsillitis in children with simple tonsillar hypertrophy were collected. The infection of Helicobacter pylori in hypertrophic tonsils was detected qualitatively by immunohistochemical technique, and the infection of Helicobacter pylori in each group was compared. Results HP was expressed in 44 of 80 cases of simple hypertrophic tonsils, and the positive rate of infection was 55.0%, while in 40 cases of chronic tonsillitis, 7 cases were HP positive. The positive rate of 17.5%.HP expression in simple tonsil hypertrophy group was significantly higher than that in control group. The difference was statistically significant (P0.05). The infection rate of HP was 55.7% in male and 53.6% in female. There was no significant difference between the two groups (P > 0.05). The HP infection rate in the tonsils with degree 鈪，

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