本文選題：鼻咽癌 + 體層攝影術(shù)�。� 參考：《廣西醫(yī)科大學(xué)》2011年碩士論文

【摘要】：目的研究不同感興趣血管選擇對(duì)鼻咽癌放療后局部復(fù)發(fā)瘤和纖維化灶CT灌注參數(shù)的影響,探討鼻咽癌放療后患者CT灌注檢查時(shí)選擇替代感興趣血管的可行性。 方法對(duì)復(fù)發(fā)組(19例)和纖維化組(11例)進(jìn)行CT灌注后,采用頸內(nèi)動(dòng)脈-頸內(nèi)靜脈、頸外動(dòng)脈-下頜后靜脈和頸外動(dòng)脈-頸內(nèi)靜脈作為三對(duì)感興趣血管測量兩組的灌注參數(shù),研究其差異性及其對(duì)復(fù)發(fā)瘤的診斷效能。 結(jié)果采用三組感興趣血管所得復(fù)發(fā)組與纖維化組的BF及BV值差異均有統(tǒng)計(jì)學(xué)意義(P0.05)而MTT及PS值差異均無統(tǒng)計(jì)學(xué)意義(P0.05)。頸內(nèi)-頸內(nèi)組灌注參數(shù)BF、BV、MTT、PS的ROC曲線下面積分別為0.909、0.947、0.677、0.703；頸外-下頜后組分別為0.938、0.967、0.648、0.679；頸外-頸內(nèi)組分別為0.861、0.890、0.641、0.656。三組感興趣血管所獲各灌注值的ROC曲線下面積差異無統(tǒng)計(jì)學(xué)意義(P0.05)。 結(jié)論采用上述三組不同感興趣血管進(jìn)行CT灌注檢查,其BF、BV對(duì)鼻咽癌放療后局部復(fù)發(fā)瘤及纖維化灶均具有鑒別診斷效能；三組不同感興趣血管可相互替代完成鼻咽癌放療后病例的CT灌注檢查。
[Abstract]:Objective to study the effect of different interested vessel selection on CT perfusion parameters of local recurrent tumor and fibrosis focus after radiotherapy in nasopharyngeal carcinoma (NPC) patients, and to explore the feasibility of replacing interested vessels in CT perfusion examination of patients with nasopharyngeal carcinoma (NPC) after radiotherapy. Methods after CT perfusion in recurrent group (19 cases) and fibrosis group (11 cases), internal carotid arterial-internal jugular vein, external jugular artery posterior mandibular vein and external jugular artery internal jugular vein were used to measure the perfusion parameters of the two groups. To study its difference and its diagnostic efficacy for recurrent tumors. Results there were significant differences in BF and BV between the recurrent group and fibrosis group (P0.05), but there was no significant difference in MTT and PS (P0.05). The area under the ROC curve of the perfusion parameter BF- BVV / MTT / PS in the intra cervical group was 0.909 / 0.947 / 0.677 / 0.703, respectively, and that in the extracervical / posterior mandibular group was 0.938 / 0.9670.648 / 0.679 and 0.8610.8900.900.641/ 0.641 / 0.656, respectively. There was no significant difference in the area under ROC curve between the three groups (P0.05). Conclusion CT perfusion examination of different interested vessels in the above three groups is effective in differential diagnosis of local recurrent tumors and fibrosis foci after radiotherapy for nasopharyngeal carcinoma. Three groups of different interested blood vessels can substitute each other to complete CT perfusion examination after radiotherapy for nasopharyngeal carcinoma.
【學(xué)位授予單位】：廣西醫(yī)科大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2011
【分類號(hào)】：R739.63

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