鼻咽癌腮腺淋巴結(jié)轉(zhuǎn)移臨床分析
發(fā)布時(shí)間:2018-06-27 19:30
本文選題:鼻咽腫瘤 + 腮腺/淋巴結(jié)。 參考:《中國(guó)腫瘤臨床》2011年02期
【摘要】:目的:探討鼻咽癌腮腺淋巴結(jié)轉(zhuǎn)移的發(fā)生概率和表現(xiàn)形式,研究其可能的轉(zhuǎn)移機(jī)制及其預(yù)后的影響。方法:收集2007年7月至2009年7月江西省腫瘤醫(yī)院初治鼻咽癌患者M(jìn)RI診斷考慮有腮腺淋巴結(jié)轉(zhuǎn)移者,分析其表現(xiàn)形式,可能的轉(zhuǎn)移機(jī)制及預(yù)后。結(jié)果:2年期間1 004例初治鼻咽癌患者中15例腮腺區(qū)結(jié)節(jié)考慮有淋巴結(jié)轉(zhuǎn)移,按擬定診斷標(biāo)準(zhǔn)14例確診為腮腺淋巴結(jié)轉(zhuǎn)移,1例排除,發(fā)生率1.4%。轉(zhuǎn)移淋巴結(jié)大部分(82%)為淺葉淋巴結(jié)。發(fā)生腮腺淋巴結(jié)轉(zhuǎn)移者絕大部分(93%)為中晚期病例,N_3患者占43%,64%患者有頸部淋巴結(jié)包膜外侵,7例患者有Ⅱa及Ⅱb區(qū)淋巴結(jié)包膜外侵融合。79%的患者有咽旁間隙不同程度侵犯,36%患者放化療前進(jìn)行過頸部干預(yù)。中位隨訪10.5個(gè)月后,14例患者6例1年內(nèi)發(fā)生遠(yuǎn)處轉(zhuǎn)移,其中2例已死亡。結(jié)論:鼻咽癌腮腺淋巴結(jié)轉(zhuǎn)移率為1.4%。其發(fā)生可能與頸部淋巴結(jié)6cm伴包膜外侵;Ⅱa、Ⅱb區(qū)淋巴結(jié)融合;咽旁間隙腫瘤占據(jù)緊鄰腮腺以及既往曾行頸部干預(yù)等有關(guān)。腮腺淋巴結(jié)轉(zhuǎn)移是鼻咽癌預(yù)后不良的因素。
[Abstract]:Objective: to investigate the probability and manifestation of parotid lymph node metastasis in nasopharyngeal carcinoma (NPC), and to study the possible metastasis mechanism and its prognostic effect. Methods: MRI diagnosis of nasopharyngeal carcinoma patients with parotid lymph node metastasis was collected from July 2007 to July 2009 in Jiangxi Cancer Hospital. Results: 15 of 1 004 nasopharyngeal carcinoma patients with nasopharyngeal carcinoma had lymph node metastasis in parotid gland. According to the diagnostic criteria, 14 cases were diagnosed as parotid lymph node metastasis, 1 case was excluded, the incidence was 1.4%. Most of the metastatic lymph nodes (82%) were superficial lobular lymph nodes. The majority (93%) of parotid lymph node metastasis were middle or late stage cases. 43 cases (64%) had cervical lymph node extracapsulation, 7 cases (鈪,
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