視網(wǎng)膜靜脈阻塞危險因素的病例對照研究
發(fā)布時間:2018-06-24 00:55
本文選題:視網(wǎng)膜中央靜脈阻塞 + 視網(wǎng)膜分支靜脈阻塞 ; 參考:《新疆醫(yī)科大學》2013年碩士論文
【摘要】:目的:探討近一年內(nèi)新疆醫(yī)科大學第一附屬醫(yī)院眼科視網(wǎng)膜靜脈阻塞(RVO)患者的人口學特點及其與全身和局部危險因素的關(guān)系。方法:采用回顧性病例對照研究。病例組為93例經(jīng)眼底熒光造影或眼底照相確診的未接受治療的RVO初發(fā)患者,對照組為86例健康體檢者,既往無眼底血管疾病史且年齡、性別、民族構(gòu)成與病例組大體一致。病例組根據(jù)眼底表現(xiàn)類型分為視網(wǎng)膜中央靜脈阻塞(CRVO)和視網(wǎng)膜分支靜脈阻塞(BRVO)。將各組間全身及眼局部疾病等危險因素用統(tǒng)計學方法比較。結(jié)果:RVO是多發(fā)于40歲及以上的中老年人的一種嚴重危害視力的疾病。病例組高血壓(OR5.963;95%CI:2.438-14.586)和高密度脂蛋白HDL降低(OR53.167;95%CI:13.277-212.905)的發(fā)生率顯著高于對照組,而在糖尿病、高膽固醇血癥、高甘油三脂血癥、低密度脂蛋白高、青光眼、吸煙等方面與對照組無統(tǒng)計學顯著差異(p0.05)。CRVO組較BRVO組中男性多、視力差。結(jié)論:高血壓和血清高密度脂蛋白降低是RVO的獨立危險因素,積極診治全身病對RVO的防治有重要意義。
[Abstract]:Objective: to investigate the demographic characteristics of patients with retinal vein occlusion (RVO) in the first affiliated Hospital of Xinjiang Medical University in recent years and its relationship with systemic and local risk factors. Methods: a retrospective case-control study was conducted. 93 patients with RVO were diagnosed by fundus fluorescein angiography or fundus radiography, and 86 healthy persons in the control group. The patients had no history of fundus vascular disease and had no history of fundus vascular disease. The age, sex, ethnic composition and ethnic composition of the group were roughly the same as those of the case group. The patients were divided into central retinal vein occlusion (CRVO) and retinal branch vein occlusion (BRVO) according to their fundus manifestations. The risk factors of systemic and ocular diseases were compared by statistical method. Results: RVO is a serious vision-threatening disease in the middle-aged and older people over 40 years old. The incidence of hypertension (OR 5.963-95 CI: 2.438-14.586) and decreased HDL (OR53.167 ~ 95CI: 13.277-212.905) in the case group was significantly higher than that in the control group, while in diabetes, hypercholesterolemia, hypertriglyceridemia, high LDL, glaucoma, There was no significant difference in smoking between CRVO group and control group (p0.05). Conclusion: hypertension and decrease of serum high density lipoprotein are independent risk factors of RVO. Active diagnosis and treatment of systemic diseases is of great significance in the prevention and treatment of RVO.
【學位授予單位】:新疆醫(yī)科大學
【學位級別】:碩士
【學位授予年份】:2013
【分類號】:R774.1
【參考文獻】
相關(guān)期刊論文 前1條
1 高偉,王雨生;視網(wǎng)膜靜脈阻塞病因?qū)W研究進展[J];中國實用眼科雜志;2005年06期
,本文編號:2059242
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