本文選題：眼反應(yīng)分析儀 + 角膜滯后量��； 參考：《汕頭大學(xué)》2010年碩士論文

【摘要】：目的:測量角膜生物力學(xué)特性在近視眼患者中的改變及評估角膜生物力學(xué)特性與其他眼球生物學(xué)變量和年齡間的關(guān)系,并探測角膜生物力學(xué)特性在眼科的臨床應(yīng)用。 對象與方法:采用眼反應(yīng)分析儀測量99位成年近視眼患者(男59名,女40名,平均年齡23±4.1歲)任一眼的角膜滯后量(corneal hysteresis, CH)、角膜阻力因子量(corneal resistance factor, CRF)、角膜補償性眼壓值(cornea-compensated intraocular pressure, IOPcc)及Goldmann相關(guān)性眼壓值(Goldmann-correlated intraocular pressure, IOPg),用角膜測厚儀測量中央角膜厚度(central corneal thickness, CCT),用IOL-Master測量眼軸,由全自動驗光儀獲取患者屈光度數(shù)及角膜曲率。應(yīng)用單元及多元線性回歸分析方法分析眼內(nèi)壓、年齡,中央角膜厚度、眼軸及角膜生物力學(xué)特性之間的關(guān)系。 結(jié)果:角膜滯后量為9.74±1.37mmHg,角膜阻力因子量為9.55±1.54mmHg。在單元線性回歸分析中,角膜滯后量和角膜阻力因子量與年齡、中央角膜厚度及IOPg之間存在相關(guān)關(guān)系(P值均0.05),而它們并不隨角膜曲率的變化而變化(P值均0.05)。角膜滯后量還與眼軸,屈光度數(shù)間存在明顯的相關(guān)關(guān)系(P0.05),相關(guān)系數(shù)分別為-0.262及0.222,而角膜阻力因子量與眼軸、屈光度數(shù)之間無明顯相關(guān)關(guān)系(P0.05)。多元線性回歸分析中,除外IOPg,角膜滯后量隨著眼軸、CCT及年齡的變化而變化。而角膜阻力因子量仍然隨著年齡、中央角膜厚度、IOPg的變化而變化。 結(jié)論:角膜滯后量與角膜阻力因子量隨著CCT的變薄和年齡的增加而降低。角膜滯后量隨著眼軸的增長及近視度數(shù)的增加而下降,而角膜阻力因子量并不隨著眼軸或近視度數(shù)的變化而變化。
[Abstract]:Objective: to measure the changes of corneal biomechanical properties in myopia patients and to evaluate the relationship between corneal biomechanical properties and other ocular biological variables and age, and to explore the clinical application of corneal biomechanical properties in ophthalmology. Participants and methods: 99 adult myopia patients (59 males, 40 females) were measured by eye response analyzer. Mean age (23 鹵4.1 years) of corneal hysteresistics, chicks, corneal resistance factor, cornea-compensated intraocular pressure, IOPcc) and Goldmann associated intraocular pressure value Goldmann-correlated intraocular pressure, IOP, central corneal thickness, central corneal, etc. Thickness, CCT, IOL-Master measurement of eye axis, The diopter and corneal curvature were obtained by automatic optometry. The relationship between intraocular pressure (IOP), age, central corneal thickness, ocular axis and corneal biomechanical properties was analyzed by unit and multivariate linear regression analysis. Results: the corneal lag was 9.74 鹵1.37 mm Hg and the corneal resistance factor was 9.55 鹵1.54 mm Hg. In unit linear regression analysis, there was a correlation between corneal lag, corneal resistance factor and age, central corneal thickness and IOPg (P = 0.05), but they did not change with the change of corneal curvature (P = 0.05). There was also a significant correlation between corneal hysteresis and ocular axis and diopter, with correlation coefficients of -0.262 and 0.222, respectively. However, there was no significant correlation between corneal resistance factor and axial and diopter numbers (P 0.05). In multivariate linear regression analysis, except IOPg, corneal lag changed with the change of CCT and age. However, the corneal resistance factor still changes with age, central corneal thickness and IOPg. Conclusion: the amount of corneal lag and corneal resistance factor decrease with CCT thinning and age increasing. The corneal hysteresis decreased with the increase of the axis and the degree of myopia, but the corneal resistance factor did not change with the change of the axis or the degree of myopia.
【學(xué)位授予單位】：汕頭大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2010
【分類號】：R778.1

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