本文選題：大前庭水管綜合征 + 前庭誘發(fā)的肌源性電位　； 參考：《福建醫(yī)科大學(xué)》2011年碩士論文

【摘要】：目的 通過記錄、分析大前庭水管綜合征(LVAS)患者前庭誘發(fā)的肌源性電位(VEMP)、主觀垂直視覺檢查(SVV)、冷熱試驗和純音測聽(PTA),了解LVAS患者的球囊、橢圓囊、前庭功能(主要是水平半規(guī)管功能)及其傳導(dǎo)通路的功能狀況以及與聽力學(xué)特點的關(guān)系。 方法 分別對22例(42患耳)LVAS患者組和20例正常組行VEMP、SVV、冷熱試驗及純音測聽等檢查,結(jié)合臨床癥狀比較分析其檢查結(jié)果。所得結(jié)果用SPSS13.0統(tǒng)計軟件進行統(tǒng)計學(xué)分析。 結(jié)果 LVAS患者組42患耳中25耳(占59.5%)VEMP表現(xiàn)為高振幅和(或)低閾值。在LVAS患者組中VEMP低閾值組前庭水管內(nèi)徑平均值為(4.30±0.53)mm,其中19耳主觀聽力較易受外界原因或發(fā)熱致顱內(nèi)壓增高的改變而波動。42患耳純音測聽有30耳(占71.4%)表現(xiàn)為低中頻(2KHz以下)存在明顯氣骨導(dǎo)差的混合性聾。LVAS患者組與正常組VEMP檢查的P13、N23平均潛伏期無顯著差異(P0.05),而兩組患者VEMP平均振幅及平均閾值存在明顯差異(P0.01); LVAS患者組與正常組SVV檢查及冷熱試驗檢查無統(tǒng)計學(xué)意義(P0.05)。 結(jié)論 1、大多LVAS患者前庭誘發(fā)的肌源性電位(VEMP)表現(xiàn)為高振幅和(或)低閾值,其純音測聽(PTA)表現(xiàn)為低中頻存在明顯氣骨導(dǎo)差的混合性聾。這可能與“第三窗”的存在有關(guān)。 2、在LVAS患者中,VEMP閾值較低者,其前庭水管平均內(nèi)徑值較大,主觀聽力也易受外界原因或發(fā)熱致顱內(nèi)壓增高的改變而波動。而純音聽力損失程度跟前庭水管內(nèi)徑平均值無相關(guān)性,與VEMP振幅的大小及閾值的高低亦無相關(guān)性。 3、LVAS患者組VEMP檢查結(jié)果與正常組存在顯著差異,而冷熱試驗及SVV檢查結(jié)果與正常組無明顯差異。從而推測變異的大前庭水管可能只是使球囊的功能受到影響,而對橢圓囊功能和前庭功能(主要是水平半規(guī)管功能)無明顯影響。
[Abstract]:Purpose By recording and analyzing vestibular evoked myogenic potentials (VEMPV), subjective vertical visual examination (VVV), cold and hot test and pure tone audiometry (PTAA) in patients with large vestibular aqueduct syndrome (LVASS), we studied the balloon and elliptical sac of patients with LVAS. The functional status of vestibular function (mainly horizontal semicircular canal) and its conduction pathway and its relationship with audiological characteristics. Method VEMPV SVV, cold and hot test and pure tone audiometry were performed in 22 patients with LVAS of 42 ears and 20 normal subjects. The results were compared with clinical symptoms. The results were analyzed by SPSS13.0 software. Result In the LVAS group, 25 of 42 affected ears showed high amplitude and / or low threshold value (59.5%)VEMP). In the LVAS group, the average vestibular aqueduct diameter in the VEMP low threshold group was 4.30 鹵0.53 mm, of which 19 ears were more susceptible to fluctuations due to external causes or increased intracranial pressure due to fever. There was no significant difference in the average latency of P13 N23 between the patients with LVAS and the normal group, but there was a significant difference in the mean amplitude and threshold of VEMP between the two groups (P 0.01). There was no significant difference between SVV and cold and hot test in normal group (P 0.05). Conclusion 1. The vestibular evoked myogenic potential (VEMPP) in most LVAS patients showed high amplitude and / or low threshold, and the pure tone audiometry showed mixed deafness with obvious air-bone conductance difference at low intermediate frequency. This may have something to do with the existence of the third window. 2. In LVAS patients with lower threshold value, the vestibular aqueduct average diameter was larger, and subjective hearing was easily fluctuated by the change of intracranial pressure caused by external causes or fever. However, there was no correlation between pure tone hearing loss and the average diameter of vestibular aqueduct, nor with the amplitude and threshold of VEMP. 3There was significant difference between VEMP and normal group, but there was no significant difference in cold and hot test and SVV between the two groups. It is speculated that the large vestibular aqueduct may only affect the function of the balloon, but not the function of the elliptical sac and vestibular vestibule (mainly the horizontal semicircular canal).
【學(xué)位授予單位】：福建醫(yī)科大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2011
【分類號】：R764.3

【引證文獻】

相關(guān)博士學(xué)位論文 前1條

1 劉紅梅;眩暈癥的中醫(yī)證候相關(guān)因素與療效評價臨床研究[D];中國中醫(yī)科學(xué)院;2012年

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本文編號：1908216