球后注射曲安奈德治療后鞏膜炎的臨床觀察
發(fā)布時間:2018-04-28 23:35
本文選題:后鞏膜炎 + 曲安奈德; 參考:《吉林大學》2011年碩士論文
【摘要】:目的: 評價球后注射曲安奈德(TA)治療后鞏膜炎的臨床療效。 方法: 回顧性分析2007年1月-2010年12月間診治的后鞏膜炎患者17例17眼,患者均經(jīng)球后注射曲安奈德20mg,每兩周一次,連續(xù)治療2-3個月,隨訪觀察治療前后的視力、眼底、眼壓、眼B超檢查和部分患者的熒光素眼底血管造影(FFA)、光學相干斷層掃描(OCT)檢查。隨訪3個月-1年。 結果: 到最后一次隨訪時,所有患者經(jīng)治療后眼紅、眼周疼痛等癥狀消失。視力提高12眼(70.6%),視力不變5眼(29.4%)。治療前及最后一次隨訪時,平均視力為0.32、0.79(P0.05)。B超檢查后鞏膜厚度(4.354±1.55)mm、(1.25+0.45)mm(P0.05),后鞏膜及筋膜水腫消失,“T”形征消失。FFA示治療后視網(wǎng)膜的熒光素滲漏明顯減輕。OCT示視網(wǎng)膜神經(jīng)上皮層復位,視網(wǎng)膜水腫消失,脈絡膜皺褶消失。所有患者隨訪期間眼壓均≤21mmHg。2例患者治療后3-6個月后鞏膜炎復發(fā)。 結論: 1、球后注射曲安奈德可有效治療后鞏膜炎。2、球后注射曲安奈德治療后鞏膜炎操作簡便、安全性高,無嚴重糖皮質激素全身副作用和局部注射并發(fā)癥發(fā)生。
[Abstract]:Objective: To evaluate the clinical effect of retrobulbar injection of triamcinolone acetonide (TAA) in the treatment of posterior scleral inflammation. Methods: From January 2007 to December 2010, 17 patients (17 eyes) with posterior scleral inflammation were treated with triamcinolone acetonide 20mg by retrobulbar injection. The visual acuity, fundus and intraocular pressure were observed after 2 to 3 months of continuous treatment. Ophthalmic ultrasonography and fluorescein fundus angiography (FFAA) and optical coherence tomography (Oct) were performed in some patients. The patients were followed up for 3 months to 1 year. Results: By the last follow-up, all patients were treated with eye redness and eye pain. Visual acuity was improved in 12 eyes (70.6%) and unchanged in 5 eyes (29.4%). Before treatment and at the last follow-up, the average visual acuity was 0.32 鹵0.79 P0.05. Scleral thickness was 4.354 鹵1.55mm / 1.25 0.45mm / P0.05, edema of posterior sclera and fascia disappeared, and "T" sign disappeared. FFA showed that the leakage of fluorescein in retina decreased significantly after treatment. Oct showed that retinal nerve epithelium was reattached. Retinal edema disappeared and choroidal folds disappeared. All patients with intraocular pressure 鈮,
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