本文關(guān)鍵詞： 鼻咽腫瘤 放射療法 生存質(zhì)量 影響因素　出處：《新疆醫(yī)科大學(xué)》2010年碩士論文　論文類型：學(xué)位論文

【摘要】： 目的:評估鼻咽癌放療后無進(jìn)展生存者的生存質(zhì)量及相關(guān)影響因素,探討調(diào)強(qiáng)放療技術(shù)(IMRT)在改善鼻咽癌放療后患者生存質(zhì)量的意義。方法:參考FACT-HN量表,制定49項(xiàng)內(nèi)容的“鼻咽癌患者生存質(zhì)量調(diào)查問卷”。問卷調(diào)查2004年1月至2008年12月我院收治的有完整資料并經(jīng)復(fù)查無進(jìn)展的96例鼻咽癌患者放療后的生存質(zhì)量。通過SPSS16.0軟件包處理數(shù)據(jù),應(yīng)用多元線性回歸分析生存質(zhì)量影響因素,將患者分為IMRT組及常規(guī)放療組(CRT組),采用秩和檢驗(yàn)比較兩組特殊癥狀及治療副反應(yīng)領(lǐng)域評分。結(jié)果:鼻咽癌放療后無進(jìn)展生存者生存質(zhì)量總得分為66.6±9.7,得分最低為功能狀況。特殊癥狀及治療副反應(yīng)主要體現(xiàn)在不能進(jìn)食固體食物、吞咽困難、口干、聲音嘶啞方面。性別、年齡、婚姻、文化程度、家庭月人均收入、臨床分期及放療技術(shù)為生存質(zhì)量獨(dú)立影響因素。IMRT組及CRT組在進(jìn)食情況、口干、聲音嘶啞、交流情況、頭暈頭痛、耳鳴聽力下降、齲齒、頸部活動(dòng)受限、張口困難、記憶力下降、味覺減退方面的差異有統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論:性別、年齡、婚姻、文化程度、家庭月人均收入、臨床分期、放療技術(shù)在多個(gè)維度上影響著鼻咽癌放療后無進(jìn)展生存者的生存質(zhì)量。調(diào)強(qiáng)放療技術(shù)在改善生存質(zhì)量方面優(yōu)于常規(guī)放療技術(shù)。
[Abstract]:Objective: the quality of life and related factors of impact assessment of nasopharyngeal carcinoma after radiotherapy for progression free survival, of intensity-modulated radiotherapy (IMRT) in improving the quality of life of patients with nasopharyngeal carcinoma after radiotherapy. Methods: the FACT-HN scale, making 49 item "questionnaire of the quality of life in patients with nasopharyngeal carcinoma. The questionnaire survey from January 2004 to December 2008 in our hospital from the complete data and the review of 96 cases of progression free survival of patients with nasopharyngeal carcinoma after radiotherapy treatment. Quality of data through the SPSS16.0 software package, using multiple linear regression analysis of the factors affecting the quality of life, the patients were divided into IMRT group and conventional radiotherapy group (CRT group), rank sum test was used to compare two groups of special adverse symptoms and the treatment field score. Results: no survivors of nasopharyngeal carcinoma after radiotherapy quality of life total score progression was 66.6 + 9.7, the lowest score for functional status. Special symptoms and treatment side effects Mainly eat solid food, not in dysphagia, xerostomia, hoarseness. Gender, age, marriage, education level, family income per capita, clinical staging and radiotherapy are independent influencing factors of.IMRT group and CRT group in the eating, dry mouth, hoarseness, communication, dizziness and headache, tinnitus and hearing fall, dental caries, neck activity limitation, trismus, memory decline, decline the taste difference was statistically significant (P0.05). Conclusion: gender, age, marriage, education level, family monthly income per capita, clinical stage, radiotherapy quality of life in multiple dimensions affect the progression free survival after radiotherapy of nasopharyngeal carcinoma. IMRT technology in improving the quality of life is better than conventional radiotherapy techniques.

【學(xué)位授予單位】：新疆醫(yī)科大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2010
【分類號】：R739.63

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本文編號：1450948