消鳴湯合氟桂利嗪治療神經(jīng)性耳鳴的臨床觀察
本文關(guān)鍵詞:消鳴湯合氟桂利嗪治療神經(jīng)性耳鳴的臨床觀察 出處:《福建中醫(yī)藥大學(xué)》2014年碩士論文 論文類型:學(xué)位論文
更多相關(guān)文章: 消鳴湯 氟桂利嗪 神經(jīng)性耳鳴 臨床療效
【摘要】:目的:通過對(duì)消鳴湯合氟桂利嗪治療神經(jīng)性耳鳴臨床療效的觀察,探討消鳴湯在治療神經(jīng)性耳鳴方面的療效,為神經(jīng)性耳鳴的治療提供一種中醫(yī)藥思維。方法:將符合納入標(biāo)準(zhǔn)的神經(jīng)性耳鳴患者60例,按隨機(jī)對(duì)照原則分為治療組與對(duì)照組。其中治療組30例39耳,采用口服中藥(消鳴湯加減)合氟桂利嗪治療;對(duì)照組30例40耳,采用口服氟桂利嗪治療。按照制定的療效評(píng)定標(biāo)準(zhǔn),對(duì)治療2周、4周(1個(gè)療程)及停藥后1個(gè)月隨訪的臨床療效進(jìn)行觀察。結(jié)果: 1.治療2周后,治療組總有效率為61.54%,對(duì)照組總有效率為45.00%,經(jīng)統(tǒng)計(jì)學(xué)分析兩組有效率P=0.1050.05,無統(tǒng)計(jì)學(xué)意義,說明兩組治療神經(jīng)性耳鳴療效無顯著差異。 2.治療4周后,治療組總有效率為84.62%,對(duì)照組總有效率為62.50%,經(jīng)統(tǒng)計(jì)學(xué)分析兩組有效率P=0.0100.05,有統(tǒng)計(jì)學(xué)意義,說明治療組療效優(yōu)于對(duì)照組。 3.停藥1個(gè)月后對(duì)患者進(jìn)行臨床隨診,治療組總有效率為79.49%,對(duì)照組總有效率為55.00%,經(jīng)統(tǒng)計(jì)學(xué)分析兩組有效率P=0.0120.05,有統(tǒng)計(jì)學(xué)意義,說明治療組療效優(yōu)于對(duì)照組。 結(jié)論: 1.治療組與對(duì)照組治療神經(jīng)性耳鳴均有一定的療效。 2.治療4周及停藥1個(gè)月后隨訪,治療組在改善癥狀及整體療效方面均優(yōu)于對(duì)照組,表明消鳴湯合氟桂利嗪治療神經(jīng)性耳鳴有較好的療效。 3.消鳴湯合氟桂利嗪治療神經(jīng)性耳鳴具有較好療效,且無不良反應(yīng),是安全有效的中藥方劑,可為神經(jīng)性耳鳴的治療提供中醫(yī)藥思維。
[Abstract]:Objective: To observe the cancellation of Ming decoction combined with flunarizine in the treatment of clinical neurological tinnitus, explore the effect of Decoction in the treatment of Xiao Ming nervous tinnitus, a traditional Chinese medicine thinking for the treatment of nervous tinnitus. Methods: 60 patients met the inclusion criteria of nervous tinnitus were randomly divided for the treatment group and control group. The treatment group 30 cases 39 ears, using traditional Chinese medicine (Xiao Ming Decoction) and flunarizine treatment; control group 30 cases of 40 ears with oral administration of flunarizine. According to the curative effect evaluation standard, on the treatment of 2 weeks, 4 weeks (1 sessions) and withdrawal after 1 months of follow-up, the clinical efficacy were observed:
1. after 2 weeks of treatment, the total effective rate of the treatment group was 61.54%, and the total effective rate of the control group was 45%. After statistical analysis, the effective rate of the two groups was P=0.1050.05, which was not statistically significant, indicating that there was no significant difference between the two groups in the treatment of neurotic tinnitus.
2. after 4 weeks of treatment, the total effective rate of the treatment group was 84.62%, and the total effective rate of the control group was 62.50%. After statistical analysis, the effective rate of the two groups was P=0.0100.05, which was statistically significant, indicating that the curative effect of the treatment group was better than that of the control group.
3. after stopping the drug for 1 months, the patients were followed up clinically, the total effective rate of the treatment group was 79.49%, and the total effective rate of the control group was 55%. After statistical analysis, the effective rate of the two groups was P=0.0120.05, which was statistically significant, indicating that the curative effect of the treatment group was better than that of the control group.
Conclusion:
1. the treatment group and the control group have a certain effect in the treatment of neurogenic tinnitus.
Follow up 2. for 4 weeks and 1 months after drug withdrawal, the treatment group in improving symptoms and overall efficacy were better than the control group, that has a good effect in eliminating Ming decoction combined with flunarizine in the treatment of nervous tinnitus.
Xiao Ming 3. decoction combined with flunarizine in the treatment of nervous tinnitus has good curative effect, and no adverse reactions, is a safe and effective prescription of traditional Chinese medicine, traditional Chinese medicine can provide a thinking for treating nervous tinnitus.
【學(xué)位授予單位】:福建中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】:碩士
【學(xué)位授予年份】:2014
【分類號(hào)】:R764.45
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