OBJECTIVE To determine the functional role of hydrogen sulfide（H₂S） in protecting against mitochondrial dysfunction in heart failure through the inhibition of Ca²⁺/calmodulin-dependent protein kinaseⅡ（Ca MKⅡ） using wild type and CSE knockout mouse models.METHODS Continuous subcutaneous injection isoprenaline(7.5 mg·kg^-1 per day),once a day for 4 weeks to induce heart failure in male C57BL/6（6-8 weeks old） mice and CSE-/-mice.150 μmol·L^-1 H₂O... 

【文章來源】：中國藥理學(xué)與毒理學(xué)雜志. 2017,31(10)北大核心

【文章頁數(shù)】：1 頁


本文編號：2976603