【摘要】：目的觀察不同類型高血壓患者脈壓、脈壓指數(shù)與肱踝動脈脈搏波傳導(dǎo)速度(baPWV)和踝臂血壓指數(shù)(ABI)的相關(guān)性。方法入選2015年1月至2017年3月初診為原發(fā)性高血壓的患者260例為觀察組,同期行體檢的健康人群220人為對照組。計算和比較對照組與觀察組[不同高血壓類型:單純收縮期高血壓組(ISH)、單純舒張期高血壓組(IDH)、收縮期舒張期高血壓組(SDH);不同脈壓:脈壓(收縮壓-舒張壓,mm Hg)≤50組、51~60組、60組;不同脈壓指數(shù)(脈壓/收縮壓):0.4組、0.4~0.5組、0.5組]baPWV和ABI水平的差異。結(jié)果觀察組患者的收縮壓、舒張壓、脈壓和脈壓指數(shù)高于對照組,baPWV水平高于而ABI水平低于對照組(均P0.05)。高血壓類型中,ISH組baPWV水平最高而ABI水平最低,SDH組與IDH組和對照組baPWV、ABI比較差異有統(tǒng)計學(xué)意義(均P0.05),IDH組和對照組baPWV、ABI比較差異無統(tǒng)計學(xué)意義(P0.05)。不同脈壓和脈壓指數(shù)亞組的baPWV水平與ABI水平存在差異,脈壓和脈壓指數(shù)越大者,baPWV越高而ABI水平越低(均P0.05)。Pearson線性相關(guān)分析顯示,baPWV與ABI呈負(fù)相關(guān)(r=-0.784,P0.05);調(diào)整年齡、BMI、血脂等影響因素后,行偏相關(guān)分析,兩者仍呈負(fù)相關(guān)(r=-0.766,P0.05)。以baPWV或ABI為因變量,年齡、血脂、血壓、血糖和BMI為自變量進(jìn)行多元線性逐步回歸分析顯示,脈壓(β=0.323或β=-0.407)和脈壓指數(shù)(β=0.352或β=-0.420)是baPWV增加或ABI減少的影響因素(均P0.05)。結(jié)論不同類型高血壓患者baPWV和ABI水平存在差異,ISH組baPWV水平最高而ABI水平最低,脈壓和脈壓指數(shù)越大者baPWV越高而ABI水平越低。
[Abstract]:Objective to observe the correlation between pulse pressure, pulse pressure index and brachial artery pulse wave conduction velocity (baPWV) and ankle brachial blood pressure index (ABI) in patients with different types of hypertension. Methods 260 patients with essential hypertension from January 2015 to March 2017 were selected as observation group, and 220 healthy people who underwent physical examination at the same time were selected as control group. Calculation and comparison of control group and observation group [different types of hypertension: simple systolic hypertension group (ISH), simple diastolic hypertension group (IDH), systolic diastolic hypertension group (SDH); Different pulse pressure: pulse pressure (systolic blood pressure-diastolic blood pressure, mm Hg) 鈮，

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