動(dòng)脈導(dǎo)管的開閉及其細(xì)胞分子機(jī)制
發(fā)布時(shí)間:2019-05-17 22:27
【摘要】:正動(dòng)脈導(dǎo)管是一種連接于降主動(dòng)脈近端和左肺動(dòng)脈起始部的血管結(jié)構(gòu)~([1-2])。對(duì)于胎兒循環(huán),動(dòng)脈導(dǎo)管開放是必須的,血液經(jīng)此通路從高壓肺動(dòng)脈流入低壓主動(dòng)脈。出生后10~15h,伴隨自主呼吸和肺循環(huán)阻力下降,流經(jīng)動(dòng)脈導(dǎo)管血液逐漸減少,管壁平滑肌收縮而自行閉合。80%兒童約在生后3個(gè)月完成
[Abstract]:The positive ductus arteriosus is a vascular structure connected to the proximal end of the descending aortic artery and the origin of the left pulmonary artery. For fetal circulation, the opening of ductus arteriosus is necessary, through which blood flows from high hypertension pulmonary artery to hypotension aorta. At 10: 15 h after birth, with the decrease of spontaneous respiration and pulmonary circulation resistance, the blood flow through ductus arteriosus decreased gradually, and the smooth muscle of the wall contracted and closed itself. 80% of the children completed it about 3 months after birth.
【作者單位】: 華中科技大學(xué)同濟(jì)醫(yī)學(xué)院附屬協(xié)和醫(yī)院心血管外科;Institute
【基金】:國家自然科學(xué)基金重點(diǎn)項(xiàng)目資助(No.31330029)
【分類號(hào)】:R54
,
本文編號(hào):2479451
[Abstract]:The positive ductus arteriosus is a vascular structure connected to the proximal end of the descending aortic artery and the origin of the left pulmonary artery. For fetal circulation, the opening of ductus arteriosus is necessary, through which blood flows from high hypertension pulmonary artery to hypotension aorta. At 10: 15 h after birth, with the decrease of spontaneous respiration and pulmonary circulation resistance, the blood flow through ductus arteriosus decreased gradually, and the smooth muscle of the wall contracted and closed itself. 80% of the children completed it about 3 months after birth.
【作者單位】: 華中科技大學(xué)同濟(jì)醫(yī)學(xué)院附屬協(xié)和醫(yī)院心血管外科;Institute
【基金】:國家自然科學(xué)基金重點(diǎn)項(xiàng)目資助(No.31330029)
【分類號(hào)】:R54
,
本文編號(hào):2479451
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