【摘要】：動脈粥樣斑塊中泡沫細(xì)胞的形成與巨噬細(xì)胞膽固醇的轉(zhuǎn)運密切相關(guān),巨噬細(xì)胞膽固醇轉(zhuǎn)運是膽固醇逆轉(zhuǎn)運中的一個重要過程,它可清除外周組織過多的膽固醇,對維持細(xì)胞內(nèi)膽固醇穩(wěn)定、延緩動脈粥樣硬化的發(fā)生發(fā)展有著重要意義.這個過程涉及到許多轉(zhuǎn)運相關(guān)蛋白的作用,如三磷酸腺苷結(jié)合盒轉(zhuǎn)運體A1/G1、載脂蛋白A-Ⅰ、膽固醇脂轉(zhuǎn)運蛋白、卵磷脂膽固醇酰基轉(zhuǎn)移酶等.本文就巨噬細(xì)胞膽固醇轉(zhuǎn)運過程中相關(guān)蛋白的作用做一綜述,以期為動脈粥樣硬化相關(guān)疾病的防治研究提供新的思路.
[Abstract]:The formation of foam cells in atherosclerotic plaques is closely related to the transport of cholesterol in macrophages. Cholesterol transport in macrophages is an important process in reversing cholesterol transport. It is of great significance to maintain the stability of intracellular cholesterol and delay the occurrence and development of atherosclerosis. This process involves the roles of many transporter proteins, such as adenosine triphosphate binding cassette transporter A1 / G1, apolipoprotein A- 鈪，

本文編號：2412468