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應用二維斑點追蹤評估高血壓患者左室肥厚對右心室功能的影響

發(fā)布時間:2018-12-15 10:16
【摘要】:目的:應用二維斑點追蹤成像(two-dimensional speckle tracking imaging,2D-STI)技術定量評價原發(fā)性高血壓患者左室肥厚對右心室功能的影響。方法:收集我院確診為原發(fā)性高血壓的患者共60例,將左室質(zhì)量指數(shù)(left ventricular mass index,LVMI),男性≥115 g/m~2,女性≥95 g/m~2的患者分左室肥厚組(B組30例),其余為無肥厚組(A組30例)。行常規(guī)超聲及二維斑點追蹤檢查并檢測右心室功能指標,包括心室大小、左室壁厚度、左室射血分數(shù)(left ventricular ejection fraction,LVEF)、三尖瓣環(huán)收縮期位移(tricuspid annular plane systolic excursion,TAPSE)、右室面積變化率(right ventricular fractional area change,RVFAC)、左室全局縱向峰值收縮期應變(left ventricular global longitudinal peak systolic strain,LVGLS)及右心室游離壁及間隔的各節(jié)段縱向峰值收縮應變。結果:2組間心室大小、LVEF、TAPSE、RVFAC均無統(tǒng)計學差異(P0.05)。B組室壁厚度及左室質(zhì)量指數(shù)顯著高于A組。B組LVGLS及右心室游離壁及間隔的各節(jié)段縱向峰值收縮應變均明顯低于A組(P0.05)。LVGLS與TAPSE、RVFAC、右心室游離壁基底段、中段、心尖段及間隔的基底段、中段、心尖段縱向峰值收縮應變呈正相關(r分別為0.606、0.333、0.379、0.289、0.384、0.500、0.515、0.317,P0.05);LVMI與TAPSE、RVFAC無明顯相關,與右心室游離壁基底段、中段、心尖段及間隔的基底段、心尖段縱向峰值收縮應變呈負相關(r分別為-0.318、-0.305、-0.328、-0.340、-0.268,P0.05)。結論:斑點追蹤可定量評價原發(fā)性高血壓患者左室肥厚對右心室功能的影響,且優(yōu)于常規(guī)超聲。左室肥厚及左室整體功能損傷可間接影響右心室功能。
[Abstract]:Aim: to quantitatively evaluate the effects of left ventricular hypertrophy on right ventricular function in patients with essential hypertension by two dimensional speckle tracing imaging (two-dimensional speckle tracking imaging,2D-STI). Methods: a total of 60 patients with essential hypertension in our hospital were divided into two groups: left ventricular mass index (left ventricular mass index,LVMI), male 鈮,

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