【摘要】：目的探討尼可地爾對高齡非ST段抬高型急性心肌梗死患者心功能和左室重構(gòu)的影響。方法選取高齡非ST段抬高型急性心肌梗死患者96例,隨機(jī)分為觀察組(48例)和對照組(48例),均行心肌梗死綜合治療。在綜合治療基礎(chǔ)上,觀察組口服尼可地爾5 mg/次,3次/d。兩組均治療3個月。觀察兩組治療前后血清腦鈉肽(BNP)、血管緊張素Ⅱ(AngⅡ)、左室射血分?jǐn)?shù)(LVEF)、左室舒張末期內(nèi)徑(LVEDD)、舒張早期二尖瓣前葉峰流速(E峰)、舒張晚期二尖瓣前葉峰流速(A峰)以及E/A值。結(jié)果治療3個月,觀察組LVEF、E峰、E/A較對照組升高,LVEDD、A峰、BNP、AngⅡ較對照組降低,差異有統(tǒng)計學(xué)意義(P均0.05)。結(jié)論尼可地爾能有效保護(hù)高齡非ST段抬高型急性心肌梗死患者的心功能,預(yù)防左室重構(gòu)。
[Abstract]:Objective to investigate the effects of nicorandil on cardiac function and left ventricular remodeling in elderly patients with non-ST segment elevation acute myocardial infarction. Methods 96 elderly patients with non ST segment elevation acute myocardial infarction were randomly divided into observation group (48 cases) and control group (48 cases). On the basis of comprehensive treatment, the observation group took Nicodil 5 times, 3 times a day. Both groups were treated for 3 months. Serum brain natriuretic peptide (BNP), angiotensin 鈪，

本文編號：2319953