【摘要】：目的:探討冠心病發(fā)病風(fēng)險與牙齒缺失數(shù)目之間的相關(guān)關(guān)系。方法:選取2016年5~11月因胸痛于山西省心血管病醫(yī)院心內(nèi)科住院的506名患者為研究對象,對其進行統(tǒng)一問卷調(diào)查及口腔臨床檢查,記錄基本信息、全身情況、口腔狀況。依據(jù)納入標準,最終納入328例研究對象,根據(jù)冠脈造影結(jié)果,將其分為非冠心病組(主要血管管腔直徑狹窄程度50%)、單支病變組、雙支及以上病變組進行相關(guān)性分析。結(jié)果:單因素分析結(jié)果顯示,年齡,性別,吸煙史,牙齦指數(shù),缺牙數(shù)目差異均有統(tǒng)計學(xué)意義(P0.05)。ordinal logistic回歸分析顯示,缺牙數(shù)目為冠心病發(fā)病的主要危險因素,與無缺牙相比,缺牙數(shù)目為1~5顆時,冠心病發(fā)病風(fēng)險增加83%(OR=1.825,95%CI=1.074-3.1),當缺牙數(shù)目超過5顆以上時,冠心病發(fā)病風(fēng)險增加1.65倍(OR=2.65,95%CI=1.471-4.956)。結(jié)論:對于本研究的心內(nèi)科住院人群,缺牙數(shù)目可能是冠心病發(fā)病風(fēng)險增加的獨立危險指標,并且隨著牙齒缺失數(shù)目的增多,風(fēng)險隨之升高;隨著年齡增加,風(fēng)險增加;男性的風(fēng)險較女性高。
[Abstract]:Objective: to investigate the relationship between the risk of coronary heart disease and the number of tooth loss. Methods: 506 patients who were hospitalized in the Department of Cardiology of Shanxi Cardiovascular Disease Hospital from May to November 2016 were selected as the research objects. The subjects were investigated with a unified questionnaire and clinical examination of stomatology to record the basic information, general situation and oral condition. According to the inclusion criteria, 328 patients were included. According to the results of coronary angiography, they were divided into non-coronary heart disease group (50% stenosis degree of main vascular lumen diameter), single vessel lesion group, double vessel disease group and above lesion group for correlation analysis. Results: univariate analysis showed that there were significant differences in age, sex, smoking history, gingival index and the number of missing teeth (P0.05). Ordinal logistic regression analysis showed that the number of missing teeth was the main risk factor of coronary heart disease, compared with no missing teeth. The risk of coronary heart disease (OR=1.825,95%CI=1.074-3.1) increased by 83% (OR=1.825,95%CI=1.074-3.1) when the number of teeth was 1 or 5, and the risk of coronary heart disease (OR=2.65,95%CI=1.471-4.956) increased by 1.65 times when the number of teeth was more than 5. Conclusion: the number of missing teeth may be an independent risk indicator for increasing the risk of coronary heart disease, and the risk increases with the increase of the number of missing teeth, and the risk increases with the increase of age. Men are at higher risk than women.
【作者單位】： 山西醫(yī)科大學(xué)口腔醫(yī)學(xué)系;山西省心血管病醫(yī)院心內(nèi)科;
【基金】：國家自然科學(xué)基金項目(編號:81271144、31050002)
【分類號】：R541.4
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本文編號：2293837