【摘要】：目的應用超聲心動圖評估孤立性室間隔基底段肥厚(IBSH)的高血壓患者左心室及流出道形態(tài)及血流動力學特點。方法使用超聲心動圖測量193例IBSH及200例非IBSH高血壓患者的左心室射血分數(shù)(LVEF)、短軸縮短率(FS)、左心室質量指數(shù)(LVMI)、室間隔基底段厚度(IVSB)、室間隔中間段厚度(IVSM)、室間隔心尖段厚度(IVSA)、左心室后壁厚度(LVPWT)、收縮期及舒張期二尖瓣附著平面與主動脈夾角(Angle)、靜息及多巴酚丁胺負荷下左心室流出道最大血流速度(LVOT-V_(max))、壓力階差(PG_(mean)),對比兩組間上述參數(shù)測值差異。結果 IBSH組與非IBSH組間IVSB[(15.1±1.6)比(12.2±1.4)mm]、IVSM[(9.3±0.9)比(10.7±1.3)mm]、IVSA[(10.3±1.1)比(10.9±0.9)mm]、LVMI[(69.5±12.3)比(77.3±14.8)g/m~2]差異有統(tǒng)計學意義(P0.01);LVPWT[(9.5±0.7)比(9.4±0.8)mm]、FS[(35.7±4.3)%比(35.4±3.1)%]及靜息狀態(tài)下兩組LVOT-V_(max)[(1.7±0.9)比(1.6±0.9)m/s]、PG_(mean)[(8.1±1.2)比(7.9±0.9)mm Hg]差異無統(tǒng)計學意義(均P0.05);多巴酚丁胺藥物負荷下IBSH組LVOT-V_(max)[(3.0±0.4)比(2.0±0.3)m/s]、PG_(mean)[(21.6±1.7)比(10.6±0.5)mm Hg]測值明顯大于非IBSH組(均P0.05)。結論靜息狀態(tài)下IBSH患者無左心室流出道血流動力學異常,但在負荷狀態(tài)下可引起左心室流出道梗阻。
[Abstract]:Objective to evaluate the morphologic and hemodynamic characteristics of left ventricle and outflow tract in hypertensive patients with isolated basal segment hypertrophy of ventricular septum (IBSH) by echocardiography. Methods left ventricular ejection fraction (LVEF),) shortening rate of left ventricular ejection fraction (LVEF),) was measured by echocardiography in 193 patients with IBSH and 200 patients with non IBSH hypertension. (FS), left ventricular mass index (LVMI),) was used to measure the thickness of the basal segment of the ventricular septum (LVMI),) and the thickness of the middle segment of the ventricular septum (IVSM),) of the ventricular septum. Segmental thickness (IVSA), left ventricular posterior wall thickness (LVPWT), systolic and diastolic mitral valve attachment plane and aortic angle (Angle), rest and dobutamine load left ventricular outflow tract maximal flow velocity (LVOT-V_ (max), pressure step difference (PG_ (mean),) were compared between the two groups. 緇撴灉 IBSH緇勪笌闈濱BSH緇勯棿IVSB[(15.1鹵1.6)姣，

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