發(fā)布時(shí)間：2018-08-27 09:20

【摘要】：目的探討急性ST段抬高型心肌梗死(STEMI)患者血管生成素樣蛋白(Angptl)-4血清水平與在進(jìn)行首次急診經(jīng)皮冠狀動(dòng)脈介入(PCI)手術(shù)后無復(fù)流現(xiàn)象之間的關(guān)系。方法 41例首次發(fā)生急性STEMI患者,入院后均按指南要求行急診PCI。根據(jù)校正的TIMI血流分級(jí)(CTFC)將患者分為無復(fù)流組(CTFC≥40幀)和對(duì)照組(CTFC40幀),抽取入院時(shí)血樣,檢測Angptl-4。對(duì)出現(xiàn)無復(fù)流的危險(xiǎn)因素進(jìn)行Logistic分析。結(jié)果①兩組患者在肌酸激酶峰值、N末端腦鈉肽前體(NT-proB NP)峰值、罪犯血管、高敏C反應(yīng)蛋白(hs-CRP)、Angptl-4水平存在顯著差異(P0.05)。②NT-proB NP、hs-CRP及Angptl-4水平與心肌梗死患者是否出現(xiàn)無復(fù)流密切相關(guān)(OR=3.967,P0.05;OR=2.737,P0.05;OR=0.468,P0.05)。結(jié)論Angptl-4水平與CTFC評(píng)價(jià)的急診PCI手術(shù)患者的無復(fù)流現(xiàn)象有關(guān),其可能具有改善無復(fù)流的作用。
[Abstract]:Objective to investigate the relationship between the serum level of angiopoietin-like protein (Angptl) -4) in patients with acute ST segment elevation myocardial infarction (STEMI) and no reflow after the first emergency percutaneous coronary intervention (PCI). Methods 41 patients with acute STEMI were treated with emergency PCI. according to the guidelines. Patients were divided into no reflow group (CTFC 鈮，

本文編號(hào)：2206828