高血壓患者鹽攝入量與夜間血壓和早期腎損害的關(guān)系
發(fā)布時間:2018-07-24 15:02
【摘要】:目的:通過對24h尿鈉的檢測,判斷個體每日攝鹽量,并探討高血壓患者鹽攝入量與夜間血壓水平和早期腎損害的關(guān)系。方法:選擇2016年5月至2017年4月遵義醫(yī)學(xué)院附屬醫(yī)院高血壓門診就診的初診未治療高血壓患者180例,其中男性91例,女性89例。年齡18~83歲。根據(jù)日均攝鹽量分為A組(5g,n=145)與B組(≤5g,n=35)。用Spearman相關(guān)分析鹽攝入量與早期腎損害的關(guān)系,多元線性回歸和偏相關(guān)分析影響早期腎損害的危險因素。結(jié)果:男性高血壓患者日均攝鹽量高于女性高血壓患者。A組患者早期腎損害檢出率為31.7%,B組患者早期腎損害檢出率為8.6%。日均攝鹽量與白晝平均收縮壓、白晝平均舒張壓、夜間平均收縮壓、夜間平均舒張壓均呈正相關(guān)(r=0.200,P0.05;r=0.225,P0.05;r=0.207,P0.01;r=0.273,P0.01);與24h尿微量白蛋白呈正相關(guān)(r=0.350,P=0.000)。白晝平均收縮壓、白晝平均舒張壓、夜間平均收縮壓、夜間平均舒張壓與24h尿微量白蛋白均呈正相關(guān)(r=0.298,P0.01;r=0.232,P0.01;r=0.228,P0.01;r=0.234,P0.01)。多元線性回歸、偏相關(guān)分析提示日均攝鹽量、24h尿鈉/尿鉀、心率及夜間平均舒張壓是早期腎損害的影響因素[β=7.717(95%CI 5.934~9.500),P0.01;β=-6.234(95%CI-9.677~-2.790),P0.01;β=0.697(95%CI 0.154~1.241),P0.05;β=0.662(95%CI 0.032~1.293),P0.05]。結(jié)論:日均攝鹽量與夜間血壓水平呈正相關(guān),是高血壓患者早期腎損害的影響因素。
[Abstract]:Objective: to determine the daily salt intake and the relationship between salt intake and nocturnal blood pressure and early renal damage in patients with hypertension. Methods: from May 2016 to April 2017, 180 patients (91 males and 89 females) with untreated hypertension were selected from outpatient clinic of affiliated Hospital of Zunyi Medical College. The age is 1883. According to the daily average salt intake, group A (5 g) and group B (鈮,
本文編號:2141753
[Abstract]:Objective: to determine the daily salt intake and the relationship between salt intake and nocturnal blood pressure and early renal damage in patients with hypertension. Methods: from May 2016 to April 2017, 180 patients (91 males and 89 females) with untreated hypertension were selected from outpatient clinic of affiliated Hospital of Zunyi Medical College. The age is 1883. According to the daily average salt intake, group A (5 g) and group B (鈮,
本文編號:2141753
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