本文選題：原發(fā)性高血壓 + 紅細(xì)胞增多��； 參考：《青海大學(xué)》2016年碩士論文

【摘要】：目的:通過對EH及其并發(fā)紅細(xì)胞增多患者動態(tài)血壓的監(jiān)測,探討EH患者BP水平和紅細(xì)胞增多的關(guān)系;通過對上述患者UA、Hs-CRP和FMD的檢測,探討UA、Hs-CRP和FMD水平與高血壓及其合并紅細(xì)胞增多的關(guān)系;通過對不同紅細(xì)胞數(shù)量的EH患者的UA、Hs-CRP和FMD值進(jìn)行比較,探討EH并發(fā)紅細(xì)胞增多組紅細(xì)胞數(shù)量與UA、Hs-CRP和FMD的相關(guān)性。方法:研究對象來自2014年12月-2015年12月青海大學(xué)附屬醫(yī)院的EH病人及其并發(fā)紅細(xì)胞增多者。分為高血壓組(A組)34例,男18例,女16例,平均歲數(shù)54.47±5.75歲;高血壓合并紅細(xì)胞增多組(B組)31例,男20例,女11例,平均歲數(shù)52.39±7.68歲。采集受試者的病史,檢測UA、Hs-CRP、FMD、FPG、TCH、TG、24SBP、24DBP、RBC和HGB,分析比較兩組病人一般臨床指標(biāo)的差異,和兩組病人UA、Hs-CRP、FMD水平變化及B組紅細(xì)胞水平與UA、Hs-CRP和FMD相關(guān)性。結(jié)果:一般資料、24SBP、24DBP和24△BP差兩組比較,差異無統(tǒng)計(jì)學(xué)意義(均P0.05)。兩組UA、Hs-CRP比較,B組高于A組,FMD低于A組,差異有統(tǒng)計(jì)學(xué)意義(P0.05),Pearson分析結(jié)果顯示B組RBC與UA、Hs-CRP呈正性相關(guān)(r=0.92,r=0.94,P0.05),與肱動脈介導(dǎo)的血管內(nèi)皮功能(FMD)呈負(fù)性相關(guān)(r=-0.97,P0.05)。結(jié)論:病人RBC與UA、Hs-CRP、FMD存在相關(guān)性。紅細(xì)胞增多可能是UA、Hs-CRP、FMD的影響因素�？刂萍t細(xì)胞數(shù)量對EH患者血壓控制及其不良心血管事件的發(fā)生有重要意義。
[Abstract]:Objective: to investigate the relationship between BP level and erythrocytosis in EH patients by monitoring ambulatory blood pressure (ABBP) in EH patients, and to detect UAHs-CRP and FMD in EH patients. To investigate the relationship between the levels of UAHs-CRP and FMD and hypertension and their association with erythrocytosis, to compare the values of UAHs-CRP and FMD in EH patients with different erythrocyte counts, and to explore the correlation between the number of RBC and UAHs-CRP and FMD in EH complicated with EH. Methods: EH patients from the affiliated Hospital of Qinghai University from December 2014 to December 2015 and their patients with polycythemia were studied. The patients were divided into hypertension group (group A, n = 34), male (n = 18), female (n = 16, mean age 54.47 鹵5.75 years), hypertension with polycythemia (group B, n = 31), male (n = 20), female (n = 11), mean age (52.39 鹵7.68 years). The patients' history was collected, and the RBC and HGBs of TCHG (TCHG) 24SBPU 24DBPU and HGBwere detected, and the changes of UAHs-CRPU FMD and the correlation between RBC and UAHs-CRP and FMD in group B were compared between the two groups. Results: there was no significant difference between 24 SBP 24 DBP and 24 BP difference in general data (P0.05). The FMD of group B was higher than that of group A (P 0.05). Pearson analysis showed that there was a positive correlation between RBC and UAHs-CRP in group B (P 0.05), and a negative correlation with vascular endothelial function (FMD) mediated by brachial artery (P 0.05). Conclusion: there is a correlation between RBC and FMD in UAV Hs-CRP. Erythrocythemia may be the influencing factor of FMD in UAV Hs-CRP. Controlling the number of erythrocytes is of great significance to the control of blood pressure and the occurrence of adverse cardiovascular events in EH patients.
【學(xué)位授予單位】：青海大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2016
【分類號】：R544.11;R555.1

【參考文獻(xiàn)】

相關(guān)期刊論文 前2條

1 金玉華;劉爭建;張寅;周軍;王立志;張雪紅;;高海拔地區(qū)紅細(xì)胞增多對原發(fā)性高血壓患者血壓和心臟重構(gòu)的影響[J];臨床薈萃;2009年11期

2 付敏,李樹華,石洪金,董衛(wèi)東,于永強(qiáng);伴和不伴紅細(xì)胞增多的阻塞性睡眠呼吸暫停綜合征患者臨床對比研究[J];臨床耳鼻咽喉科雜志;2003年12期

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本文編號：2092007