本文選題：心房顫動(dòng) + 認(rèn)知障礙��； 參考：《中國循環(huán)雜志》2017年10期

【摘要】：目的:探討住院心房顫動(dòng)(房顫)患者血管性認(rèn)知功能障礙(VCI)的發(fā)生率及相關(guān)危險(xiǎn)因素。方法:選擇蘭州大學(xué)第二醫(yī)院住院的房顫患者303例,根據(jù)簡(jiǎn)易智能狀態(tài)檢查量表(MMSE)評(píng)分分為無VCI組216例,VCI組87例。評(píng)估住院房顫患者VCI的發(fā)生率,并對(duì)VCI進(jìn)行單因素及多因素分析。結(jié)果:與無VCI組比較,VCI組年齡較大,CHA2DS2-VASC評(píng)分≥2分、持續(xù)/永久性房顫、合并糖尿病及心力衰竭的比例、收縮壓、平均動(dòng)脈壓、脈壓,左心房前后徑及血肌酐較高,男性比例及左心室舒張末內(nèi)徑較低,差異具有統(tǒng)計(jì)學(xué)意義(P0.05或P0.001)。住院房顫患者VCI發(fā)生率為40.3%,隨著年齡的增大、CHA2DS2-VASC評(píng)分的增高,VCI發(fā)生率增加,女性VCI發(fā)生率高于男性,持續(xù)及永久性房顫患者VCI發(fā)生率高于陣發(fā)性房顫患者(P0.05或P0.001)。多元線性回歸分析顯示,年齡(OR=-0.1135,95%CI:-0.1708~-0.0562,P=0.0001)、女性(OR=-1.2528,95%CI:-2.2056~-0.3000,P=0.0105)、文化水平(小學(xué)OR=3.2193,95%CI:1.8446~4.5940,P0.0001;初中及以上OR=5.9104,95%CI:4.6055~7.2154,P0.0001)、心力衰竭(OR=-1.9357,95%CI:-3.5522~-0.3192,P=0.0196)、腦卒中(OR=-1.6349,95%CI:-2.7517~-0.5181,P=0.0044)及左心房前后徑(OR=-0.1252,95%CI:-0.1962~-0.0541,P=0.0006)與住院房顫患者VCI發(fā)生相關(guān)。結(jié)論:住院房顫患者VCI發(fā)生率高,高齡、女性、較低文化水平、心力衰竭、腦卒中及左心房前后徑擴(kuò)大是房顫患者發(fā)生VCI的相關(guān)危險(xiǎn)因素。
[Abstract]:Objective: to investigate the incidence and risk factors of vascular cognitive impairment (VCI) in hospitalized patients with atrial fibrillation (AF). Methods: 303 patients with atrial fibrillation were selected from the second Hospital of Lanzhou University. According to the MMSE score, they were divided into two groups: 216 patients without VCI and 87 patients with VCI. To evaluate the incidence of VCI in patients with atrial fibrillation, and to analyze the single factor and multivariate analysis of VCI. Results: compared with the VCI group, the older VCI group with CHA2DS2-VASC score 鈮，

本文編號(hào)：2088954