本文選題：宗氣指數(shù) + 代謝當(dāng)量��； 參考：《福建中醫(yī)藥大學(xué)》2017年碩士論文

【摘要】：課題來源:中國(guó)中醫(yī)科學(xué)院中醫(yī)基礎(chǔ)理論研究所第十批研究生課題(課題號(hào):YZ-1666)。目的:本課題通過探討冠心病患者宗氣指數(shù)(ZQI)與心肺運(yùn)動(dòng)試驗(yàn)產(chǎn)生的代謝當(dāng)量(MET)、攝氧量(V02)、氧脈搏(02pulse)間的相關(guān)性,進(jìn)一步驗(yàn)證宗氣指數(shù)在評(píng)估心肺功能的意義,以期能為評(píng)價(jià)宗氣理論指導(dǎo)冠心病診療的效果研究提供實(shí)證依據(jù)。方法:根據(jù)納入標(biāo)準(zhǔn)選取北京市第一中西醫(yī)結(jié)合醫(yī)院的59名冠心病患者,使用頭戴式宗氣指數(shù)測(cè)量?jī)x測(cè)量受試者ZQI,同時(shí)使用心肺功能儀測(cè)得MET、V02、02pulse。根據(jù)心肺運(yùn)動(dòng)試驗(yàn)程序,由"熱身"至"運(yùn)動(dòng)"的變化節(jié)點(diǎn)取值MET-1、V02-1、02pulse-1,及同步獲得的ZQI-1;由"運(yùn)動(dòng)"至"恢復(fù)"的變化節(jié)點(diǎn)取值MET-2、V02-2、02pulse-2,及同步獲得的ZQI-2;及2個(gè)時(shí)點(diǎn)的數(shù)值差獲得MET差值、V02差值、O2pulse差值。運(yùn)用epidata數(shù)據(jù)庫對(duì)數(shù)據(jù)錄入與整理。運(yùn)用多元線性回歸方法探討ZQI(ZQI-1、ZQI-2、ZQI差值)與同組 MET(MET-1、MET-2、MET 差值)、V02(V02-1、V02-2、V02 差值)、02pulse(02pulse-1、02pulse-2、02pulse差值)的相關(guān)性。并根據(jù)心肺功能的影響因素,探討影響因素與模型方程中各個(gè)變量之間的相關(guān)性,對(duì)所擬合的模型進(jìn)行驗(yàn)證。結(jié)果:一般情況:共納入59例病例。男性46例(78.0%),女性13例(22.0%),男女比例3.54:1。年齡為29-84歲,平均年齡(60±11.58)歲。受試者的BMI介于(18.6-30.8)Kg/m2,平均值為(24.7±2.79)Kg/m2。冠心病保守治療19例(32.2%)、PCI術(shù)后組33例(55.9%)、CABG術(shù)后組6例(10.2%),另有1例受試者曾先接受過CABG術(shù),術(shù)后6個(gè)月接受了PCI術(shù)。受試者合并的疾病主要包括心腦血管系統(tǒng)疾病、呼吸系統(tǒng)疾病、代謝類疾病、運(yùn)動(dòng)相關(guān)疾病等。受試者中,近1個(gè)月來無用藥記錄的共3例,其余56例受試者1個(gè)月內(nèi)服用1至9種不等的藥物治療,有服用β受體阻斷藥的共41例(69.5%),未使用β受體阻斷藥的18例(30.5%)。ZQI與MET、V02、02pulse的相關(guān)性分析:ZQI與V02和02pulse具有中度相關(guān)性,可擬合三組模型分別為①(ZQI-1)=85.826-0.127×(VO2-1)+9.172×(O2pulse-1)。且該模型中,V02-1 與 02pulse-1 對(duì) ZQI-1 的作用相當(dāng)。②(ZQI-2)=26.987-0.097×(VO2-2)+12.095×(O2pulse-2)。且該模型中,V02-2 對(duì) ZQI-2 的作用較大。③(ZQI 差值)=-34.431-0.071 ×(V02差值)+8.809×(O2pulse差值)。且該模型中,V02差值對(duì)ZQI差值的作用較大。經(jīng)驗(yàn)證,BMI與ZQI-1成負(fù)相關(guān),與V02-1成正相關(guān);年齡與ZQI-2成正相關(guān),與 V02-2、O2pulse-2 成負(fù)相關(guān)。結(jié)論:①ZQI與V02、02pulse存在相關(guān)性,與MET相關(guān)性較小。ZQI可用于評(píng)估心肺功能。②本研究中,BMI和年齡為ZQI與V02的共同影響因素。
[Abstract]:Source: the tenth graduate program of Institute of basic Theory of TCM, Chinese Academy of traditional Chinese Medicine (Project No.: YZ-1666). Objective: to investigate the correlation between ZQI and metabolic equivalent (met), oxygen uptake (V02) and oxygen pulse (02pulse) in patients with coronary heart disease (CHD), and to further verify the significance of ZQI in evaluating cardiopulmonary function. In order to evaluate the effect of Zong Qi theory guiding coronary heart disease diagnosis and treatment to provide an empirical basis. Methods: according to the inclusion criteria, 59 patients with coronary heart disease were selected from Beijing first Integrated traditional Chinese and Western Medicine Hospital. ZQI was measured by using the headset Zong gas index meter, and METV02C02pulsewas measured by cardiopulmonary function instrument. According to the cardiopulmonary exercise test procedure, The change nodes from "warm up" to "motion" are valued MET-1 / V02-1 / 02pulse-1, and ZQI-1obtained simultaneously; MET-2V02-2O2pulse-2 from "motion" to "recovery", and ZQI-2obtained simultaneously; and the value difference of MET-1V02 is obtained by O2pulse difference. Use epidata database to input and organize data. The correlation between ZQI (ZQI-1ZQI-2ZQI difference) and MET-2 (MET-2MET-2MET difference) V02 (V02-1 / V02-2V02) was studied by using multivariate linear regression method, and the correlation between ZQI (ZQI) and MET (02pulse-102pulse-2pulse-2pulse) was investigated. According to the influencing factors of cardiopulmonary function, the correlation between the influencing factors and the variables in the model equation was discussed, and the fitted model was verified. Results: general situation: a total of 59 cases were included. There were 46 males (78.0%) and 13 females (22.0%). The average age was (60 鹵11.58) years. The BMI of the subjects ranged from (18.6-30.8) kg / m ~ (2), with an average of (24.7 鹵2.79) kg / m ~ (2). There were 19 cases (32.2%) of coronary heart disease treated conservatively, 33 cases (55.9%) in PCI group, 6 cases (10.2%) in CABG group, and 1 case (10.2%) in CABG group. One patient received CABG first and PCI was performed 6 months after PCI. The main diseases included cardiovascular and cerebrovascular diseases, respiratory diseases, metabolic diseases, exercise-related diseases and so on. Of the subjects, 3 had no record of drug use in the past month, while the remaining 56 patients took one to nine different drug treatments within one month. There were 41 cases (69.5%) who took 尾 receptor blockers, 18 cases (30.5%) without 尾 receptor blockers. The correlation between ZQI and METV0202pulse was moderate. The three groups of models were 1 (ZQI-1) 85.826-0.127 脳 (VO2-1) 9.172 脳 (O2pulse-1), the results showed that: 1 (ZQI-1) was 85.826-0.127 脳 (VO2-1) 9.172 脳 (O2pulse-1). The effect of V02-1 on ZQI-1 is equal to that of 02pulse-1 on ZQI-1. The effect of V02-1 on ZQI-1 is 26.987-0.097 脳 (VO2-2) 12.095 脳 (O2pulse-2). In this model, the effect of V02-2 on ZQI-2 is greater. 3 (ZQI difference) -34.431-0.071 脳 (V02 difference) 8.809 脳 (O2pulse difference). In this model, the effect of V02 difference on ZQI difference is significant. BMI was negatively correlated with ZQI-1 and positively correlated with V02-1, age was positively correlated with ZQI-2 and negatively correlated with V02-2O2pulse-2. Conclusion there is a correlation between V02ZQI and V02O2pulse, and a small correlation with met. ZQI can be used to evaluate the influence factors of BMI and age of ZQI and V02 in the study of cardiopulmonary function .2 in this study.
【學(xué)位授予單位】：福建中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2017
【分類號(hào)】：R541.4

【相似文獻(xiàn)】

相關(guān)期刊論文 前10條

1 韓金武;安國(guó)興;;淺談宗氣在慢性阻塞性肺疾病中的運(yùn)用[J];甘肅醫(yī)藥;2010年05期

2 李艷,嚴(yán)燦;宗氣實(shí)質(zhì)探討[J];湖北中醫(yī)雜志;2000年10期

3 吉鳳霞;宗氣——生命開始的標(biāo)志[J];北京針灸骨傷學(xué)院學(xué)報(bào);2000年02期

4 張智偉;黃晶;鄭雅芳;陶功定;;試論宗氣之“宗”的命名內(nèi)涵[J];山西中醫(yī)學(xué)院學(xué)報(bào);2007年02期

5 賈海驊;王侖;趙紅霞;李海玉;;從宗氣論治勞倦的機(jī)理探討[J];中國(guó)中醫(yī)基礎(chǔ)醫(yī)學(xué)雜志;2007年05期

6 王九龍;;宗氣理論的研究進(jìn)程與思考[J];中國(guó)中醫(yī)基礎(chǔ)醫(yī)學(xué)雜志;2007年06期

7 張玉慧;;宗氣之生理初探[J];中國(guó)醫(yī)藥指南;2008年23期

8 徐寧;;淺析《內(nèi)經(jīng)》中的宗氣理論[J];湖北中醫(yī)雜志;2009年06期

9 劉煒;;宗氣理論探析及臨床應(yīng)用[J];中醫(yī)藥學(xué)報(bào);2009年06期

10 張玉慧;姜學(xué)連;魏銘;路玉良;宋為民;李雪梅;;宗氣理論臨床應(yīng)用概述[J];陜西中醫(yī);2011年05期

相關(guān)會(huì)議論文 前5條

1 崔承兵;;從中醫(yī)“保養(yǎng)宗氣理論”談高原病的預(yù)防(摘要)[A];全國(guó)鐵路第五屆疾病控制學(xué)術(shù)研討會(huì)論文集[C];2004年

2 張萬義;;試論宗氣虛-宗氣下陷是老年心血管疾病的重要病機(jī)[A];第十次中醫(yī)藥防治老年病學(xué)術(shù)交流會(huì)論文集[C];2012年

3 王仁忠;;論宗氣、心肺與鼻[A];中醫(yī)耳鼻喉學(xué)術(shù)傳承與研究論文匯編[C];2009年

4 王仁忠;;論宗氣、心肺與鼻[A];第15屆全國(guó)中醫(yī)耳鼻喉科學(xué)術(shù)研討和繼續(xù)教育年會(huì)論文匯編[C];2009年

5 洪文學(xué);陳志茹;樊鳳杰;宋佳霖;李娟;景軍;;未病學(xué)與調(diào)宗氣、調(diào)中氣和調(diào)元?dú)饫碚撗芯縖A];中國(guó)生物醫(yī)學(xué)工程進(jìn)展——2007中國(guó)生物醫(yī)學(xué)工程聯(lián)合學(xué)術(shù)年會(huì)論文集（下冊(cè)）[C];2007年

相關(guān)重要報(bào)紙文章 前2條

1 北京中醫(yī)藥大學(xué) 翟雙慶;論《內(nèi)經(jīng)》對(duì)宗氣的認(rèn)識(shí)[N];中國(guó)中醫(yī)藥報(bào);2012年

2 李忠業(yè);升補(bǔ)宗氣為心衰治療大法[N];中國(guó)中醫(yī)藥報(bào);2006年

相關(guān)博士學(xué)位論文 前3條

1 王麗華;洪廣祥運(yùn)用宗氣理論治療慢性阻塞性肺疾病穩(wěn)定期的經(jīng)驗(yàn)繼承與臨床研究[D];南京中醫(yī)藥大學(xué);2012年

2 樊茂蓉;通肺絡(luò)補(bǔ)宗氣方提高特發(fā)性肺間質(zhì)纖維化患者活動(dòng)耐力及作用機(jī)理的研究[D];中國(guó)中醫(yī)科學(xué)院;2015年

3 王仁忠;宗氣與鼻鼽發(fā)病的相關(guān)性研究[D];山東中醫(yī)藥大學(xué);2005年

相關(guān)碩士學(xué)位論文 前6條

1 張小剛;中醫(yī)宗氣理論研究[D];遼寧中醫(yī)藥大學(xué);2012年

2 劉曉烽;從“胸中大氣”探討胸痹治療新思路[D];山東中醫(yī)藥大學(xué);2015年

3 劉煒;宗氣理論探析及臨床應(yīng)用[D];北京中醫(yī)藥大學(xué);2010年

4 劉日;從宗氣論治胸痹的理論研究和病例回顧性分析[D];遼寧中醫(yī)藥大學(xué);2013年

5 張智偉;《黃帝內(nèi)經(jīng)》宗氣理論及張錫純對(duì)宗氣理論貢獻(xiàn)的應(yīng)用研究[D];黑龍江中醫(yī)藥大學(xué);2007年

6 譚雄;從宗氣下陷論治氣虛血瘀型慢性心力衰竭的臨床療效觀察[D];湖南中醫(yī)藥大學(xué);2012年

，

本文編號(hào)：2066034