本文選題：太極拳 + 健身氣功�。� 參考：《揚(yáng)州大學(xué)》2017年碩士論文

【摘要】：研究目的:本文采用太極拳及健身氣功運(yùn)動(dòng)干預(yù)社區(qū)老年原發(fā)性高血壓患者,觀察12個(gè)月運(yùn)動(dòng)干預(yù)后對(duì)受試者血壓、身體成分、血脂、炎癥因子、氣體信號(hào)分子等相關(guān)指標(biāo)的影響,分析該運(yùn)動(dòng)對(duì)社區(qū)老年原發(fā)性高血壓患者的防治效果、相互關(guān)系及相關(guān)機(jī)理,揭示運(yùn)動(dòng)防治高血壓的相關(guān)機(jī)制,拓寬太極拳及健身氣功運(yùn)動(dòng)對(duì)健康促進(jìn)的研究范疇,使其更好地服務(wù)大眾健身。研究方法:本研究篩選社區(qū)高血壓病患者32人(男8名、女24名),平均年齡為63.50±2.91歲,根據(jù)患者選擇,將其分為運(yùn)動(dòng)組和不運(yùn)動(dòng)對(duì)照組,其中運(yùn)動(dòng)組20人,不運(yùn)動(dòng)對(duì)照組12人;運(yùn)動(dòng)組在干預(yù)前對(duì)每位受試者所測(cè)的靶心率與自我疲勞分級(jí)制定個(gè)體運(yùn)動(dòng)強(qiáng)度,施以1h/天、6天/周的小強(qiáng)度太極拳及健身氣功運(yùn)動(dòng);分別檢測(cè)受試者實(shí)驗(yàn)前、運(yùn)動(dòng)6個(gè)月末、運(yùn)動(dòng)12個(gè)月末的身高、體重、體脂百分比、血壓等生理指標(biāo)以及血脂代謝(甘油三酯、總膽固醇、高密度脂蛋白膽固醇、低密度脂蛋白膽固醇),氣體信號(hào)分子(一氧化氮、一氧化碳、硫化氫),炎癥因子(腫瘤壞死因子-α、超敏C反應(yīng)蛋白、白細(xì)胞介素-6),內(nèi)皮素-1與血管緊張素II等生化指標(biāo)。研究結(jié)果:實(shí)驗(yàn)前運(yùn)動(dòng)組與對(duì)照組的各指標(biāo)均無統(tǒng)計(jì)學(xué)差異。(1)運(yùn)動(dòng)6個(gè)月末,受試者SBP、DBP均出現(xiàn)非常顯著性下降(P0.01),且SBP與對(duì)照組相比具有顯著性差異(P0.05),PP無顯著性變化;運(yùn)動(dòng)12個(gè)月末,SBP、DBP、PP均出現(xiàn)顯著性下降(P0.01、P0.05、P0.05),且SBP、PP與對(duì)照組相比均有顯著性差異(P0.01、P0.05),對(duì)照組實(shí)驗(yàn)前后無顯著性變化。(2)運(yùn)動(dòng)6個(gè)月末,受試者BMI、體脂率均出現(xiàn)顯著性下降(P0.01,P0.05);運(yùn)動(dòng)12個(gè)月末,體重指數(shù)、體脂率均出現(xiàn)非常顯著性下降(P0.01),對(duì)照組12個(gè)月末BMI較實(shí)驗(yàn)前出現(xiàn)非常顯著性上升(P0.01),而體脂率無顯著性差異。(3)運(yùn)動(dòng)6個(gè)月末,受試者血清HDL-C出現(xiàn)非常顯著性上升(P0.01),TC、TG、LDL-C呈下降趨勢(shì),但無顯著性變化;運(yùn)動(dòng)12個(gè)月末,TC、TG、LDL-C均出現(xiàn)顯著性下降(P0.05、P0.05、P0.01),HDL-C與對(duì)照組相比具有顯著性差異(P0.05),對(duì)照組實(shí)驗(yàn)前后無顯著性變化。(4)運(yùn)動(dòng)6個(gè)月末,受試者血清NO、H2S均出現(xiàn)顯著性上升(P0.01,P0.05),CO無顯著性變化,且H2S與對(duì)照組相比具有非常顯著性差異(P0.01);運(yùn)動(dòng)12個(gè)月末,NO、H2S、CO均出現(xiàn)顯著性上升(P0.01、P0.05、P0.01),與對(duì)照組相比均有顯著性差異(P0.05、P0.05、P0.01),對(duì)照組實(shí)驗(yàn)前后無顯著性變化。(5)運(yùn)動(dòng)6個(gè)月末,受試者血清TNF-α、IL-6均出現(xiàn)非常顯著性下降(P0.01),且與對(duì)照組相比均有顯著性差異(P0.05,P0.01),hs-CRP無顯著性變化;運(yùn)動(dòng)12個(gè)月末,TNF-α、IL-6、hs-CRP均出現(xiàn)非常顯著性下降(P0.01),與對(duì)照組相比均有顯著性差異(P0.01、P0.01、P0.05),對(duì)照組實(shí)驗(yàn)前后無顯著性變化。(6)運(yùn)動(dòng)6個(gè)月末,受試者血清ET-1、AngⅡ均出現(xiàn)顯著性下降(P0.01,P0.05),且ET-1與對(duì)照組相比具有顯著性差異(P0.05);運(yùn)動(dòng)12個(gè)月末,ET-1、AngⅡ均出現(xiàn)非常顯著性下降(P0.01),與對(duì)照組相比均有顯著性差異(P0.05),對(duì)照組實(shí)驗(yàn)前后無顯著性變化。(7)運(yùn)動(dòng)12個(gè)月末,SBP與LDL-C、ET-1、hs-CRP、AngⅡ呈正相關(guān)(r=0.49,P0.01;r=0.53,P0.01;r=0.46,P0.05;r=0.39,P0.05),與 NO、CO、HDL-C、H2S 呈負(fù)相關(guān)(r=0.58,P0.01;r=0.51,P0.01;r0.43,P0.05;r=0.49,P0.05);DBP 與 LDL-C、IL-6 呈正相關(guān)(r=0.39,P0.05;r=0.38,P0.05);脈壓差與 LDL-C、NO 呈負(fù)相關(guān)(r=0.51,P0.01;r=0.48,P0.01)。研究結(jié)論:通過12個(gè)月的太極拳及健身氣功運(yùn)動(dòng)干預(yù)實(shí)驗(yàn)研究,1、太極拳及健身氣功運(yùn)動(dòng)對(duì)降低原發(fā)性高血壓患者的收縮壓與舒張壓有明顯療效,并縮小脈壓差,干預(yù)過程中受試者的血壓并不是平緩下降,而是波浪式下降。該運(yùn)動(dòng)可作為結(jié)合藥物治療的輔助降壓手段。2、太極拳及健身氣功運(yùn)動(dòng)有效改善高血壓患者BMI指數(shù)與體脂率,減少體內(nèi)多余脂肪;明顯降低受試者血清LDL-C、TC和TG水平和升高HDL-C水平,對(duì)脂代謝有著積極的調(diào)節(jié)作用,有效改善血脂異常,降低心血管疾病的發(fā)生與發(fā)展。3、太極拳及健身氣功運(yùn)動(dòng)可提高高血壓患者血清氣體信號(hào)分子NO、CO、H2S水平,降低ET-1與AngⅡ水平,改善動(dòng)脈血管彈性,有效降低血壓,促進(jìn)高血壓患者的健康,可作為降壓機(jī)制之一。4、太極拳及健身氣功運(yùn)動(dòng)可降低高血壓患者血清炎癥水平,反映炎癥水平的TNF-α、hs-CRP、IL-6均明顯降低,降低高血壓導(dǎo)致的血管內(nèi)皮功能損害,從而進(jìn)一步阻止血壓的升高。
[Abstract]:The purpose of this study was to observe the effects of 12 month exercise intervention on the subjects' blood pressure, body composition, blood lipid, inflammatory factors and gas signal molecules after 12 months of exercise intervention, and to analyze the effect of the exercise on the elderly patients with primary hypertension in community. Relationship and related mechanism, reveal the related mechanism of exercise prevention and control of hypertension, broaden the research category of Taijiquan and fitness Qigong exercise to health promotion, make it better serve the public health. Research methods: This study screening 32 people of community hypertension patients (8 men, 24 women), the average age of 63.50 + 2.91 years, according to the choice of the patient, it will be The exercise group was divided into the exercise group and the non exercise control group, of which 20 people in the exercise group and 12 people in the non exercise control group; before the intervention, the exercise intensity was determined by the target rate and the self Fatigue Grade measured by each subjects, and the small intensity Taijiquan and the Fitness Qigong were performed at 1h/ days and 6 days per week. Before the test, the subjects were tested and the exercise was at the end of 6 months, respectively. Physical indexes such as height, weight, body fat percentage, blood pressure, and blood lipid metabolism (triglyceride, total cholesterol, high density lipoprotein cholesterol, low density lipoprotein cholesterol), gas signal molecules (nitric oxide, carbon monoxide, hydrogen sulfide), inflammatory factors (tumor necrosis factor - alpha, hypersensitivity C reactive protein, interleukin), and blood lipid metabolism at the end of 12 months of exercise. -6), the biochemical indexes of endothelin -1 and angiotensin II. Results: there was no statistical difference between the pre experiment group and the control group. (1) at the end of the 6 month of the exercise, the subjects had a very significant decrease in SBP and DBP (P0.01), and the SBP had significant difference (P0.05), and the PP had no significant changes compared with the control group, and the exercise was at the end of 12 months, SBP, D. BP, PP were significantly decreased (P0.01, P0.05, P0.05), and SBP, PP was significantly different from the control group (P0.01, P0.05), and there was no significant change in the control group before and after the experiment. (2) the body fat rate decreased significantly (P0.01, P0.05) at the end of the 6 months of exercise (P0.01, P0.05), and the body mass index and body fat rate were very significant at the end of the 12 months of exercise. (P0.01), in the control group, there was a significant increase in BMI at the end of 12 months (P0.01), but there was no significant difference in body fat rate. (3) at the end of the 6 month of the exercise, the serum HDL-C of the subjects increased significantly (P0.01), TC, TG, LDL-C showed a decline, but no significant change; TC, TG, LDL-C were significantly decreased at the end of the 12 months of exercise (P0.05, LDL-C) 05, P0.01), HDL-C was significantly different from the control group (P0.05), and there was no significant change in the control group before and after the experiment. (4) at the end of the 6 month of the exercise, the serum NO, H2S had a significant increase (P0.01, P0.05), CO had no significant changes, and H2S was significantly different from the control group (P0.01); NO, H2S, and H2S were all appeared at the end of the 12 months of exercise. Significantly increased (P0.01, P0.05, P0.01), compared with the control group (P0.05, P0.05, P0.01), no significant changes before and after the control group. (5) at the end of the 6 months of the exercise, the subjects serum TNF- alpha, IL-6 had a very significant decrease (P0.01), and compared with the control group, there were significant differences (P0.05, P0.01), hs-CRP has no significant changes; At the end of the 12 months of exercise, TNF- alpha, IL-6 and hs-CRP were significantly decreased (P0.01), and there were significant differences compared with the control group (P0.01, P0.01, P0.05), and there was no significant change in the control group before and after the experiment. (6) the serum ET-1 and Ang II of the subjects were significantly decreased (P0.01, P0.05) at the end of the 6 months of exercise, and ET-1 was significant compared with the control group. The difference (P0.05); at the end of the 12 months of exercise, both ET-1 and Ang II had a very significant decrease (P0.01), compared with the control group (P0.05), and there was no significant change in the control group before and after the experiment. (7) there was a positive correlation between SBP and LDL-C, ET-1, hs-CRP, Ang II at the end of the 12 months of exercise. C, H2S is negative correlation (r=0.58, P0.01; r=0.51, P0.01; r0.43, P0.05; r=0.49, P0.05); DBP and LDL-C are negative correlation. Research conclusion: through 12 months of Taijiquan and fitness Qigong exercise intervention experimental study, 1, Taijiquan and fitness Qigong Exercise has a significant effect on reducing systolic and diastolic pressure in patients with essential hypertension and narrowing the pulse pressure. The blood pressure of the subjects in the intervention process is not a flat decrease, but a wave type drop. This exercise can be used as an auxiliary antihypertensive method combined with drug therapy.2, Taijiquan and fitness Qigong exercise can effectively improve the BMI finger of hypertensive patients. The number and body fat rate, reduce the excess fat in the body, decrease the serum LDL-C, TC and TG levels and increase the level of HDL-C significantly, have positive regulation on lipid metabolism, improve blood lipid abnormality, reduce the occurrence and development of cardiovascular diseases and.3, Taijiquan and fitness Qigong exercise can improve the serum gas signal molecule NO, CO, H2S level, reducing the level of ET-1 and Ang II, improving arterial elasticity, reducing blood pressure effectively and promoting the health of hypertensive patients, can be used as one of the mechanism of blood pressure lowering.4. Taijiquan and fitness Qigong exercise can reduce the level of serum inflammation in hypertensive patients, which reflect the level of TNF- alpha, hs-CRP, IL-6 in the level of inflammation, and reduce the blood vessels caused by hypertension. Endothelial dysfunction can further prevent blood pressure from rising.
【學(xué)位授予單位】：揚(yáng)州大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2017
【分類號(hào)】：R544.1

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