本文選題：高血壓 + 中心動脈血壓��； 參考：《中國老年學(xué)雜志》2017年14期

【摘要】：目的探討老年高血壓患者中心動脈壓(CAP)與腎功能的相關(guān)性。方法年齡≥60歲高血壓患者250例,患者按年齡分為4組(60~69歲,70~79歲,80~89歲,≥90歲);分別測量外周動脈血壓(PAP)、腎功能、血脂、體重指數(shù)(BMI)等指標(biāo);采用中國人矯正的MDRD公式計算腎小球濾過率(GFR);通過HEM-9000AI脈波檢測裝置測量CAP[包括中心動脈收縮壓(CSBP)、中心動脈壓(CPP)、增強壓(AP)、反射波增強指數(shù)(AIx)];將GFR與危險因素進行多元線性回歸分析。結(jié)果肌酐、GFR、脈壓(PP)隨年齡增大而增高(P0.05);年齡、CSBP、AP、Alx、肌酐與GFR呈負相關(guān)(β=-0.105、-0.162、-0.294、-0.972、-0.887,P0.01)。結(jié)論 MAP呈增齡性改變,隨年齡的增長而增加;在PAP降低相同的情況下,MAP越高,在一定程度上提示腎功能損害越嚴重。
[Abstract]:Objective to investigate the correlation between central arterial pressure (CAP) and renal function in elderly patients with hypertension. Methods 250 patients with hypertension aged more than 60 years were divided into 4 groups according to their age. The peripheral arterial blood pressure (PAPP), renal function, blood lipids and body mass index (BMIs) were measured respectively. Using the MDRD formula corrected by the Chinese to calculate the glomerular filtration rate (GFR); using the HEM-9000AI pulse wave detection device to measure CAP [including central arterial systolic pressure (CPP), central arterial pressure (CPP), enhanced pressure (APP), reflection wave enhancement index (AIX)]; and carrying out multiple measures of GFR and risk factors. Meta-linear regression analysis. Results the creatinine GFR (PP) increased with age (P 0.05), and the age of GFR was negatively correlated with GFR (尾 -0.105) (尾 -0.105- 0.162- 0.294- 0.972U -0.887g) (P 0.01). Conclusion the changes of MAP are age-related and increase with the increase of age, and the higher the map of PAP is, the more serious the damage of renal function is to a certain extent.
【作者單位】： 四川省醫(yī)學(xué)科學(xué)院四川省人民醫(yī)院老年心內(nèi)科;
【分類號】：R544.1

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本文編號：1970623