本文選題：心肌梗死 + 性別因素　； 參考：《解放軍醫(yī)學(xué)雜志》2017年02期

【摘要】：目的 分析解放軍306醫(yī)院心臟中心急性ST段抬高型心肌梗死(STEMI)救治體系中不同性別患者之間再灌注時(shí)間延遲的分布。方法 納入2011年1月-2015年12月解放軍306醫(yī)院連續(xù)急診收治并符合入選標(biāo)準(zhǔn)的STEMI患者325例,依據(jù)性別不同分為男性組(268例)和女性組(57例),分析各急救時(shí)間,包括發(fā)病(SO)至首次醫(yī)療接觸(FMC)時(shí)間(SO-to-FMC)、轉(zhuǎn)運(yùn)時(shí)間(FMC-to-D)、FMC-to-B、導(dǎo)管室啟動(dòng)延遲時(shí)間、介入操作延遲時(shí)間、急診至球囊擴(kuò)張血管再通時(shí)間(D-to-B)等,并觀察預(yù)后。結(jié)果 盡管女性患者的院前延遲時(shí)間中位數(shù)(160.0min)和So-to-FMC中位數(shù)(100.0min)較男性(分別為119.5min和69.5min)延長(zhǎng),但差異無(wú)統(tǒng)計(jì)學(xué)意義,其余各項(xiàng)再灌注延遲時(shí)間差異也無(wú)統(tǒng)計(jì)學(xué)意義(P0.05)。女性患者合并高血壓、糖尿病者比例較高,吸煙率明顯低于男性(P0.05);兩組STEMI患者30d內(nèi)和1年內(nèi)的主要心腦血管不良事件(MACCE)發(fā)生率(男性5.22% vs 女性5.26%;男性10.82% vs 女性8.77%)差異無(wú)統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論 性別因素對(duì)再灌注延遲的影響正逐漸弱化。
[Abstract]:Objective to analyze the distribution of reperfusion time delay among patients of different genders in acute St segment elevation myocardial infarction (STEMI) treatment system in 306 Hospital of PLA. Methods from January 2011 to December 2015, 325 consecutive emergency patients with STEMI admitted to 306 Hospital of PLA from January 2011 to December 2015 were divided into male group (268 cases) and female group (57 cases) according to gender difference. The time of SO-to-FMC, FMC-to-DX, delay of catheterization, delay of interventional operation, time of recanalization from emergency to balloon dilation, etc., and prognosis were observed. Results although the median pre-hospital delay time (160.0min) and So-to-FMC median (100.0mins) in female patients were significantly longer than those in males (119.5min and 69.5 mins, respectively), the difference was not statistically significant, and there was no significant difference in the rest of reperfusion delay time (P 0.05). The incidence of major cardiovascular and cerebrovascular adverse events (5.22% in males vs 5.26% in females; 10.82% in males vs 8.77g% in females) had no significant difference between the two groups in the incidence of major cardiovascular and cerebrovascular adverse events (5.22% vs 5.26%; 10.82% vs 8.77% in females). Conclusion the effect of sex factor on reperfusion delay is weakening gradually.
【作者單位】： 解放軍306醫(yī)院心內(nèi)科;
【分類號(hào)】：R542.22

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