本文選題：老年 + 急性心肌梗死��； 參考：《中國(guó)醫(yī)學(xué)創(chuàng)新》2017年25期

【摘要】：目的:分析阿卡波糖片對(duì)老年急性心肌梗死患者心室重構(gòu)的影響。方法:選取2014年10月-2016年10月本院收治的老年急性心肌梗死疾病患者92例作為研究對(duì)象,按照隨機(jī)數(shù)字法分為對(duì)照組和治療組,每組各46例。對(duì)照組采用常規(guī)抗心肌梗死用藥方案,治療組在對(duì)照組基礎(chǔ)上加用阿卡波糖片。比較用藥前后左心室射血分?jǐn)?shù)、梗死面積、心房鈉尿肽、TNF-α等相關(guān)指標(biāo)水平的改善幅度、老年急性心肌梗死藥物治療總有效率、用藥期間出現(xiàn)的心室重構(gòu)例數(shù)、心肌功能恢復(fù)正常時(shí)間和用藥總時(shí)間、藥物不良反應(yīng)率。結(jié)果:治療組在用藥前后左心室射血分?jǐn)?shù)、梗死面積、心房鈉尿肽、TNF-α等相關(guān)指標(biāo)水平的改善幅度均顯著高于對(duì)照組,比較差異均有統(tǒng)計(jì)學(xué)意義(P0.05);治療組老年急性心肌梗死藥物治療總有效率為91.3%,高于對(duì)照組的71.7%,比較差異有統(tǒng)計(jì)學(xué)意義(P0.05);用藥期間,治療組心室重構(gòu)出現(xiàn)3例,少于對(duì)照組的11例,比較差異有統(tǒng)計(jì)學(xué)意義(P0.05);心肌功能恢復(fù)正常時(shí)間和用藥總時(shí)間均少于對(duì)照組,比較差異均有統(tǒng)計(jì)學(xué)意義(P0.05);治療組藥物不良反應(yīng)率為4.3%,顯著低于對(duì)照組的21.7%,比較差異有統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論:老年急性心肌梗死疾病患者采用阿卡波糖片進(jìn)行治療,可以有效控制心室重構(gòu)現(xiàn)象的發(fā)生,大幅度改善心肌功能,縮短用藥時(shí)間。
[Abstract]:Objective: to analyze the effect of acarbose tablets on ventricular remodeling in elderly patients with acute myocardial infarction. Methods: 92 elderly patients with acute myocardial infarction (AMI) from October 2014 to October 2016 were randomly divided into control group (n = 46) and treatment group (n = 46). The control group was treated with routine anti-myocardial infarction regimen, and the treatment group was treated with acarbose tablets on the basis of the control group. The relative indexes such as left ventricular ejection fraction (LVEF), infarct area, atrial natriuretic peptide TNF- 偽, the total effective rate of drug therapy in elderly patients with acute myocardial infarction (AMI), and the number of cases of ventricular remodeling during medication were compared before and after treatment. The time of recovery of myocardial function, the total time of medication and the rate of adverse drug reaction. Results: the improvement of left ventricular ejection fraction, infarct area and atrial natriuretic peptide TNF- 偽 in the treatment group was significantly higher than that in the control group. The total effective rate of drug therapy for elderly patients with acute myocardial infarction in the treatment group was 91.3, which was higher than that in the control group (71.7), and the difference was statistically significant (P 0.05). During the treatment period, there were 3 cases of ventricular remodeling in the treatment group, less than 11 cases in the control group. The difference was statistically significant (P 0.05), the time of normal myocardial function and the total time of medication were less than those of the control group. The adverse drug reaction rate in the treatment group was 4.3which was significantly lower than that in the control group (21.7g), and the difference was statistically significant (P 0.05). Conclusion: the treatment of senile patients with acute myocardial infarction with acarbose tablets can effectively control the occurrence of ventricular remodeling, improve myocardial function and shorten the time of medication.
【作者單位】： 云南省普洱市人民醫(yī)院;
【分類號(hào)】：R542.22

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