本文選題：參柴舒心湯 + 穩(wěn)定性心絞痛�。� 參考：《黑龍江中醫(yī)藥大學》2017年碩士論文

【摘要】：目的:觀察參柴舒心湯治療冠心病穩(wěn)定性心絞痛(氣滯血瘀證)合并焦慮癥患者臨床療效,探討其治療冠心病的有效性、安全性及對合并焦慮癥的改善情況。方法:將60例確診為冠心病穩(wěn)定性心絞痛(氣滯血瘀證)合并焦慮癥患者隨機分為治療組和對照組,每組各30例;對照組給予西醫(yī)常規(guī)基礎(chǔ)治療及心理疏導,治療組在對照組基礎(chǔ)上給予參柴舒心湯,療程為4周;觀察治療前后兩組患者心絞痛癥狀、中醫(yī)癥狀、心電圖、硝酸甘油停減率、西雅圖心絞痛量表、漢密爾頓焦慮量表的變化情況,利用SPSS20.0統(tǒng)計學軟件對數(shù)據(jù)進行分析。結(jié)果:1.治療后,治療組心絞痛積分、中醫(yī)證候積分低于對照組,差異均有統(tǒng)計學意義(p0.05);兩組心絞痛積分、中醫(yī)證候積分均比治療前降低,差異均有統(tǒng)計學意義(p0.05)。2.治療組心絞痛療效和中醫(yī)證候療效的總有效率均高于對照組,差異均有統(tǒng)計學意義(p0.05)。3.在心電圖療效方面,治療組總有效率為46.67%,對照組總有效率為33.33%,差異無統(tǒng)計學意義(p0.05)。4.在硝酸甘油停減率方面,治療組為73.33%,對照組為46.67%,差異有統(tǒng)計學意義(p0.05)。5.治療后,治療組在SAQ五大項評分方面均高于對照組,差異均有統(tǒng)計學意義(p0.05);治療后,治療組上述評分均高于治療前水平,差異均有統(tǒng)計學意義(p0.05);對照組除AS項外,余各項評分均高于治療前水平,差異均有統(tǒng)計學意義(p0.05)。6.治療后,治療組HAMA評分低于對照組,差異有統(tǒng)計學意義(p0.05);治療后兩組量表評分均低于治療前水平,差異均有統(tǒng)計學意義(p0.05);治療組療效總有效率高于對照組,差異有統(tǒng)計學意義 (p0.05)。結(jié)論:1.參柴舒心湯能夠緩解氣滯血瘀證穩(wěn)定性心絞痛合并焦慮癥患者的心絞痛癥狀,改善中醫(yī)證候。2.參柴舒心湯能夠提高氣滯血瘀證穩(wěn)定性心絞痛合并焦慮癥患者的生活質(zhì)量。3.參柴舒心湯能夠改善氣滯血瘀證穩(wěn)定性心絞痛合并焦慮癥患者的焦慮癥狀。
[Abstract]:Objective: to observe the clinical effect of Shenchaishuxin decoction in the treatment of stable angina pectoris (Qi stagnation and blood stasis syndrome) with anxiety disorder, and to explore the efficacy, safety and improvement of Shenchaishuxin decoction in the treatment of coronary heart disease. Methods: sixty patients with stable angina pectoris of coronary heart disease (Qi stagnation and blood stasis syndrome) and anxiety disorder were randomly divided into treatment group and control group with 30 cases in each group. The treatment group was treated with Shenchaisuxin decoction for 4 weeks on the basis of the control group, and the symptoms of angina pectoris, symptoms of TCM, ECG, reduction rate of nitroglycerin and Seattle angina scale were observed before and after treatment. The changes of Hamilton anxiety scale were analyzed by SPSS20.0 software. The result is 1: 1. After treatment, the scores of angina pectoris and TCM syndromes in the treatment group were lower than those in the control group, the differences were statistically significant (P 0.05), and the scores of angina pectoris and TCM syndromes in the two groups were lower than those before treatment, and the differences were statistically significant. The total effective rate of angina pectoris and TCM syndromes in the treatment group was higher than that in the control group, and the difference was statistically significant. The total effective rate of electrocardiogram was 46.67 in the treatment group and 33.33 in the control group. The stopping rate of nitroglycerin was 73.33 in the treatment group and 46.67 in the control group. The difference was statistically significant. After treatment, the scores of five items of SAQ in the treatment group were higher than those in the control group, the differences were statistically significant (P 0.05), and after treatment, the scores in the treatment group were all higher than those before treatment, and the differences were statistically significant (P 0.05). The remaining scores were higher than those before treatment, and the differences were statistically significant. After treatment, the HAMA score in the treatment group was lower than that in the control group, the difference was statistically significant (P 0.05), the score of the two groups was lower than that before treatment, and the difference was statistically significant (P 0.05). The total effective rate of the treatment group was higher than that of the control group. The difference was statistically significant (P 0.05). Conclusion 1. ShenchaiShuxin decoction can relieve the symptoms of angina pectoris associated with anxiety in patients with stable angina pectoris and improve TCM syndromes. ShenchaiShuxin decoction can improve the quality of life of patients with stable angina pectoris complicated with anxiety syndrome of qi stagnation and blood stasis syndrome. ShenchaiShuxin decoction can improve the anxiety symptoms of patients with stable angina pectoris and anxiety syndrome of qi stagnation and blood stasis syndrome.
【學位授予單位】：黑龍江中醫(yī)藥大學
【學位級別】：碩士
【學位授予年份】：2017
【分類號】：R541.4;R749.72

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