發(fā)布時(shí)間：2018-04-20 01:16

  本文選題：血脂正常 + 冠心病　； 參考：《錦州醫(yī)科大學(xué)》2017年碩士論文

【摘要】：目的1、調(diào)查中年冠心病患者的一般資料(年齡、性別、生活行為方式及血液學(xué)檢查指標(biāo)等)。2、探討血脂正常中年冠心病患者的影響因素,為冠心病的防治提供參考依據(jù)。方法1、采用現(xiàn)況調(diào)查法對(duì)錦州醫(yī)科大學(xué)附屬第一、三醫(yī)院心血管內(nèi)科經(jīng)冠狀動(dòng)脈造影檢查確診為冠心病的中年人(45-59歲)960例進(jìn)行問(wèn)卷調(diào)查。2、采用病例-對(duì)照的研究方法,收集錦州醫(yī)科大學(xué)附屬第一及第三醫(yī)院心血管內(nèi)科經(jīng)冠狀動(dòng)脈造影檢查的血脂正常中年人(45-59歲)338例病例,對(duì)照隨機(jī)選擇于體檢中心檢查的血脂正常中年人346例并進(jìn)行問(wèn)卷調(diào)查,采用非條件logistic回歸模型對(duì)影響血脂正常冠心病的因素進(jìn)行分析。結(jié)果血脂正常冠心病發(fā)生的危險(xiǎn)因素有年齡(OR=1.057,95%CI=1.009~1.106)、吸煙(OR=1.788,95%CI=1.131~2.827)、收縮壓(OR=1.021,95%CI=1.011~1.031)、低密度脂蛋白LDL(OR=20.947,95%CI=11.267~38.944);膽紅素血脂綜合指數(shù)(TC/(TBIL+HDL))(OR=504.500,95%CI=86.107~2955.852),男性(OR=1.555,95%CI=1.031~2.347);保護(hù)因素為高密度脂蛋白(OR=0.746,95%CI=0.483~0.950)。TC/(HDL+TBIL)的ROC曲線下面積(AUC)為0.671(95%CI:0.630~0.711),TC/(HDL+TBIL)預(yù)測(cè)中年血脂正常冠心病的界值為0.34,敏感度為50.3%,特異度為80.1%。結(jié)論年齡、吸煙、收縮壓、LDL、TC/(TBIL+HDL)是影響錦州地區(qū)血脂正常中年冠心病發(fā)生的重要危險(xiǎn)因素,而高密度脂蛋白是保護(hù)因素,中年男性比女性患病率高。血脂正常人群TC/(TBIL+HDL)值大于0.34,建議降血脂治療。
[Abstract]:Objective: 1. To investigate the general data (age, sex, lifestyle and hematological index) of patients with coronary heart disease (CHD) in middle age, to explore the influencing factors of normal blood lipid in middle-aged patients with coronary heart disease, and to provide reference for the prevention and treatment of coronary heart disease (CHD). Methods 1. A questionnaire survey was conducted on 960 middle-aged patients aged 45-59 years who were diagnosed as coronary artery disease by coronary angiography in the Department of Cardiovascular Medicine of the first and third affiliated hospitals of Jinzhou Medical University. A case-control study was used. A total of 338 healthy middle-aged patients aged 45-59 years with normal blood lipids were collected from the Department of Cardiovascular Medicine of the first and third affiliated Hospital of Jinzhou Medical University. 346 normal middle-aged people with normal blood lipids were randomly selected in the physical examination center and investigated by questionnaire. Non-conditional logistic regression model was used to analyze the factors affecting normal blood lipid coronary heart disease. 緇撴灉琛，

本文編號(hào)：1775584