本文選題：下肢動(dòng)脈硬化閉塞癥 + 對(duì)比劑��； 參考：《介入放射學(xué)雜志》2017年11期

【摘要】：目的探討能譜CT最佳單能量成像技術(shù)在下肢動(dòng)脈成像中個(gè)體化降低對(duì)比劑用量的可行性。方法前瞻性連續(xù)收集下肢CTA檢查患者75例,按掃描方式及對(duì)比劑用量隨機(jī)分為傳統(tǒng)CT常規(guī)劑量組、能譜CT常規(guī)劑量組及能譜CT低劑量組。傳統(tǒng)CT組、能譜常規(guī)劑量組對(duì)比劑用量為2 ml/kg,注射速率為3.5 ml/s,掃描方式、重建方法前者采用120 k Vp、濾波反投影(FBP)技術(shù),后者采用能譜模式、50%自適應(yīng)統(tǒng)計(jì)迭代重建(ASi R)技術(shù);能譜低劑量組對(duì)比劑用量、注射速率均降低20%,采用能譜模式、50%ASi R技術(shù)。檢測(cè)3組圖像靶血管CT值,并記錄對(duì)比噪聲比(CNR)、背景噪聲(BN)、劑量長(zhǎng)度乘積(DLP)、有效輻射劑量(ED)、攝碘量及注射速率,采用單因素方差分析結(jié)合Bonferroni法進(jìn)行差異性檢驗(yàn)。采用Kruskal-Wallis檢驗(yàn)對(duì)3組圖像質(zhì)量主觀評(píng)分進(jìn)行對(duì)比分析。結(jié)果本研究納入60例患者,每組20例。能譜常規(guī)劑量組圖像有著最佳CT值、CNR、BN(P0.01),但BN與能譜低劑量組間差異無統(tǒng)計(jì)學(xué)意義(P0.05);能譜低劑量組CT值、CNR除脛前動(dòng)脈(P=0.162,P=0.376)外,均高于傳統(tǒng)CT組(P0.05)。兩能譜組ED均顯著低于傳統(tǒng)CT組(P0.01),但兩能譜組間差異無統(tǒng)計(jì)學(xué)意義(P0.05)。能譜低劑量組攝碘量、注射速率均顯著低于能譜常規(guī)劑量組、傳統(tǒng)CT組(P0.01)。醫(yī)師1、2對(duì)3組圖像主觀評(píng)分分別為82分、95分、90分和80分、96分、89分,差異有統(tǒng)計(jì)學(xué)意義(H=14.954,P0.01;H=17.726,P0.01),能譜常規(guī)劑量組有最佳圖像質(zhì)量,能譜低劑量組圖像質(zhì)量?jī)?yōu)于傳統(tǒng)CT組(P0.05)。結(jié)論能譜CT最佳單能量成像與傳統(tǒng)螺旋CT相比,可提供更好的CNR及圖像質(zhì)量,在保證下肢動(dòng)脈成像臨床診斷的基礎(chǔ)上明顯降低輻射劑量,同時(shí)個(gè)性化減少對(duì)比劑攝入量。
[Abstract]:Objective to discuss the imaging in lower extremity arterial individualization in the feasibility of reducing the amount of contrast spectrum CT best single energy imaging. Methods prospective consecutive 75 cases of patients with lower extremity CTA examination, according to the scanning mode and amount of contrast were randomly divided into the traditional CT conventional dose group, CT dose group and conventional spectrum spectrum of low dose CT the traditional group. In CT group, the conventional dose group spectrum contrast agent was 2 ml/kg, the injection rate of 3.5 ml/s, scanning and reconstruction method of the former was 120 K Vp, filtered backprojection (FBP) technology, which uses the energy spectrum model, 50% adaptive statistical iterative reconstruction (ASi R) technology; low energy spectrum dose of contrast agent dosage, injection rate decreased by 20%, energy spectrum model, 50%ASi R detection technology. The 3 images of the target vessel CT value, and record the contrast to noise ratio (CNR), background noise (BN), dose length product (DLP), effective radiation dose (ED), iodine and injection speed 鐜，

本文編號(hào)：1771558