發(fā)布時間：2018-04-11 19:07

  本文選題：交警 + 血尿酸��； 參考：《中國職業(yè)醫(yī)學》2017年02期

【摘要】：目的了解男性外勤交警人群血尿酸水平,探討其高血尿酸與心血管危險因素及其聚集性之間的關(guān)系。方法采用方便抽樣方法,以1 039名廣州市男性外勤交警人群為研究對象,進行問卷調(diào)查、體格檢查和實驗室檢查。根據(jù)血尿酸水平是否偏高(420.00μmol/L)將研究對象分為高血尿酸組和對照組。結(jié)果男性外勤交警人群血尿酸水平中位數(shù)為431.00μmol/L,高血尿酸檢出率為56.3%。高血尿酸組人群外勤警齡、收縮壓、舒張壓和血清甘油三酯(TG)、總膽固醇(TC)、低密度脂蛋白膽固醇(LDL-C)、肌酐的水平均高于對照組(P0.01),高密度脂蛋白膽固醇水平低于對照組(P0.01)。多因素Logistic回歸分析顯示,調(diào)整混雜因素年齡和飲酒后,超重與肥胖、高TG和高TC男性外勤交警罹患高血尿酸的風險均高于正常者(P0.05),比值比(OR)及其95%可信區(qū)間(CI)分別為2.347(1.772~3.109)、2.040(1.517~2.743)和1.431(1.080~1.896);男性外勤交警罹患高血尿酸的風險均隨外勤警齡和血肌酐水平的增加而升高(P0.05),OR及其95%CI分別為1.028(1.004~1.054)和1.048(1.033~1.062)。男性外勤交警人群中高血尿酸者所占比例隨著心血管危險因素的增多而增多(P0.01)。男性外勤交警人群有1、2、3、4及5個以上的心血管危險因素時罹患高血尿酸的風險分別為無心血管危險因素個體的1.583、2.351、4.657、2.865和13.576倍(P0.05)。結(jié)論男性外勤交警人群罹患高血尿酸的風險與心血管危險因素密切相關(guān),其風險隨心血管危險因素聚集而增加。
[Abstract]:Objective to investigate the level of serum uric acid in male traffic police and its relationship with cardiovascular risk factors and aggregation.Methods 1 039 male traffic policemen in Guangzhou were investigated by questionnaire, physical examination and laboratory examination.The subjects were divided into hyperuricemia group and control group according to whether the level of uric acid was higher than 420.00 渭 mol / L.Results the median level of serum uric acid was 431.00 渭 mol / L and the detection rate of hyperuricemia was 56.3%.The field police age, systolic blood pressure, diastolic blood pressure, serum triglyceride TGG, total cholesterol TCU, low density lipoprotein cholesterol (LDL-C), creatinine were higher in the hyperuricuric acid group than those in the control group (P 0.01), and the level of high density lipoprotein cholesterol was lower than that of the control group (P 0.01).Multivariate Logistic regression analysis showed that, adjusted for confounding age and alcohol consumption, overweight and obesity,With the increase of the level of P0.05, the OR and 95%CI were 1.02828, 1.004, 1.054, and 1.048, 1.033, 1.062, respectively.The proportion of male traffic police with high uric acid increased with the increase of cardiovascular risk factors.The risk of hyperuricemia in male traffic police was 1.583 / 2.351and 4.6572.865 and 13.576 times respectively when there were more than 5 cardiovascular risk factors in the male field traffic police, and the risk of hyperuricemia was 13.576 times than that of the individuals without cardiovascular risk factors (P < 0.05).Conclusion the risk of hyperuricemia in male traffic police is closely related to cardiovascular risk factors, and the risk increases with the concentration of cardiovascular risk factors.
【作者單位】： 中山大學公共衛(wèi)生學院;廣州市第十二人民醫(yī)院;
【基金】：廣州市民生科技重大項目(2014Y2-00067) 廣東省“十二五”醫(yī)學重點�？�、廣州市醫(yī)學重點學科建設(shè)項目 廣州市職業(yè)環(huán)境與健康效應實驗室建設(shè)項目(2014SY000020) 廣州市“121人才梯隊工程”后備人才項目
【分類號】：R54;R589.7

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