本文選題：冠心病 + 血府逐瘀湯　； 參考：《延邊大學(xué)》2017年碩士論文

【摘要】：目的:觀察血府逐瘀湯聯(lián)合西藥治療冠心病穩(wěn)定型勞累性心絞痛(中醫(yī)辨證為胸痹心脈瘀阻型)患者,與西醫(yī)常規(guī)治療在心絞痛癥狀改善和中醫(yī)癥候變化等方面的改善情況。方法:選擇自2014年12月至2017年1月期間就診于延吉市中醫(yī)醫(yī)院門診及住院患者總計(jì)60例。病情既屬于冠心病心絞痛的西醫(yī)確診標(biāo)準(zhǔn),又符合中醫(yī)辨證胸痹心血瘀阻型。通過隨機(jī)原則將60例患者分為西醫(yī)常規(guī)治療對照組(30例)和中西醫(yī)結(jié)合治療組(30例),兩組均給予對癥治療,治療組采用中西醫(yī)結(jié)合即加減應(yīng)用血府逐瘀湯。每14天為1個(gè)療程,3個(gè)療程后進(jìn)行評估療效。將患者中醫(yī)癥候評分、心絞痛癥狀、心電圖、硝酸甘油用量作為療效評估的主要手段,對比并分析其改變。結(jié)果:兩組患者在心絞痛癥狀和中醫(yī)癥候方面比較治療前均有改善,說明兩組患者在減少心絞痛發(fā)作次數(shù)、心絞痛發(fā)作的持續(xù)時(shí)間與心絞痛發(fā)作的嚴(yán)重程度治療有效,且中西醫(yī)結(jié)合改善療效更顯著。在通過心電圖評價(jià)治療效果方面,兩組患者對比試驗(yàn)前均有正向改變,皆在心電圖表現(xiàn)上減輕心肌缺血,且中西醫(yī)結(jié)合治療組與對照組相比效果更顯著。兩組患者硝酸甘油用量與治療前比較有顯著差異,且中西醫(yī)結(jié)合治療組好于對照組。兩組患者在試驗(yàn)期間生命體征,實(shí)驗(yàn)室檢查均無異常,無胃腸道反應(yīng)、心血管不良反應(yīng)、過敏反應(yīng)。結(jié)論:血府逐瘀湯加減治療冠心病心絞痛(中醫(yī)辨證為胸痹心脈瘀阻型)與西醫(yī)常規(guī)治療,中西醫(yī)結(jié)合的試驗(yàn)結(jié)果更佳,可減少心絞痛發(fā)作次數(shù)、嚴(yán)重程度以及心絞痛發(fā)作時(shí)間,減少硝酸甘油用量從而提高患者的生命質(zhì)量,并且安全性較高。
[Abstract]:Objective: to observe the therapeutic effect of Xuefu Zhuyu decoction combined with western medicine on stable angina pectoris of coronary heart disease (TCM syndrome differentiation is chest obstruction and heart stasis type), and the improvement of angina pectoris symptoms and changes of TCM symptoms with routine treatment of western medicine.Methods: a total of 60 outpatients and inpatients were selected from December 2014 to January 2017 in Yanji traditional Chinese Medicine Hospital.The disease is not only the diagnostic standard of coronary heart disease angina pectoris, but also consistent with TCM syndrome differentiation.60 patients were randomly divided into two groups: control group (n = 30) and integrated Chinese and western medicine group (n = 30). Both groups were given symptomatic treatment, and the treatment group was treated with Xuefu Zhuyu decoction by combination of traditional Chinese and western medicine.Every 14 days as a course of treatment, 3 courses of treatment were evaluated.TCM symptom score, angina pectoris symptom, electrocardiogram and nitroglycerin dosage were compared and analyzed.Results: the symptoms of angina pectoris and symptoms of traditional Chinese medicine were improved in both groups, indicating that the two groups were effective in reducing the number of angina pectoris attack, the duration of angina pectoris attack and the severity of angina pectoris attack.And integrated Chinese and western medicine to improve the efficacy is more significant.In the evaluation of therapeutic effect by electrocardiogram, the two groups had positive changes before the contrast test, both of them alleviated myocardial ischemia in electrocardiogram, and the effect of integrated Chinese and western medicine treatment group was more significant than that of the control group.The dosage of nitroglycerin in the two groups was significantly different from that before treatment, and the combination of traditional Chinese and western medicine was better than that in the control group.There were no abnormal vital signs and laboratory findings, no gastrointestinal reactions, adverse cardiovascular reactions and allergic reactions in both groups.Conclusion: Xuefu Zhuyu decoction can be used to treat angina pectoris of coronary heart disease (syndrome differentiation of traditional Chinese medicine is the type of stagnation of heart and heart of heart) and routine treatment of western medicine. The test result of combination of traditional Chinese and western medicine is better and can reduce the frequency of angina pectoris attack.Severity and angina attack time, reducing nitroglycerin use to improve the quality of life, and high safety.
【學(xué)位授予單位】：延邊大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2017
【分類號】：R541.4
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本文編號：1737245