本文選題：頻發(fā)室性期前收縮　切入點：特發(fā)性室性早搏　出處：《軍事醫(yī)學(xué)》2017年05期

【摘要】：目的聯(lián)合心臟超聲及無創(chuàng)血流動力學(xué)檢測技術(shù)探討頻發(fā)室性期前收縮(PVC)患者經(jīng)導(dǎo)管射頻消融術(shù)(RFCA)前后心功能變化。方法選取48例特發(fā)性頻發(fā)PVC患者為試驗組,PVC總數(shù)(16 391.03±10 873.01)個/24 h,另外隨機選取55例健康查體者為對照組,分別行心臟超聲及無創(chuàng)血流動力學(xué)檢測。同時選試驗組中25例患者行RFCA治療,于術(shù)后3 d行無創(chuàng)血流動力學(xué)檢測。分別比較兩組心臟超聲及無創(chuàng)血流動力學(xué)檢測結(jié)果,及RFCA前、后3 d無創(chuàng)血流動力學(xué)檢測結(jié)果。結(jié)果所有超聲結(jié)果均無統(tǒng)計學(xué)差異。比較PVC組與對照組的無創(chuàng)血流動力學(xué)檢測結(jié)果,PVC組中心縮力指數(shù)(HI)、心搏指數(shù)(SI)、心臟指數(shù)(CI)、室縮波波幅(C)較對照組降低,差異具有統(tǒng)計學(xué)意義(P0.05),而房縮波波幅(WA)、室舒波波幅(O)、左室順應(yīng)性指數(shù)(WA/C)、舒張功能指數(shù)(O/C)較對照組升高,差異具有統(tǒng)計學(xué)意義(P0.01);比較RFCA術(shù)前與術(shù)后3 d患者無創(chuàng)血流動力學(xué)檢測結(jié)果,術(shù)后3 d患者HI、SI、CI、C水平顯著升高(P0.01),而WA、O、WA/C、O/C較術(shù)前降低,差異具有統(tǒng)計學(xué)意義。結(jié)論特發(fā)性PVC患者在病程早期其心功能可能已受損,經(jīng)RFCA可逆轉(zhuǎn)或防止患者因頻發(fā)PVC而損及心功能。
[Abstract]:Objective to investigate the changes of cardiac function before and after radiofrequency catheter ablation (RFCA) in patients with frequent ventricular presystolic PVC (PVC) by combination of echocardiography and noninvasive hemodynamic measurement.Methods 48 patients with idiopathic PVC were selected as the experimental group (16 391.03 鹵10 873.01) / 24 h, and 55 healthy persons were randomly selected as the control group. The echocardiography and noninvasive hemodynamic examination were performed respectively.At the same time, 25 patients in the trial group were treated with RFCA, and non-invasive hemodynamic examination was performed 3 days after operation.The results of echocardiography and noninvasive hemodynamic examination were compared between the two groups, and the results of noninvasive hemodynamics before and 3 days after RFCA were compared.Results there was no statistical difference in all ultrasound results.The results of noninvasive hemodynamic examination in PVC group and control group were compared. The central contractility index, cardiac systolic index, cardiac index and amplitude of ventricular contraction wave in PVC group were lower than those in control group.The difference was statistically significant (P 0.05), while atrial contraction wave amplitude, ventricular diastolic wave amplitude, left ventricular compliance index, diastolic function index and diastolic function index were higher than those in control group.The difference was statistically significant (P 0.01), and the results of noninvasive hemodynamic examination before and after 3 days of RFCA were compared. The level of CIIC C in patients with RFCA 3 days after operation was significantly higher than that before operation (P 0.01), but it was lower than that before operation, and the difference was statistically significant.Conclusion the cardiac function of idiopathic PVC patients may have been damaged in the early stage of the disease, and RFCA can reverse or prevent the damage of cardiac function due to frequent PVC.
【作者單位】： 河北北方學(xué)院;空軍總醫(yī)院;
【分類號】：R541.7

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