發(fā)布時(shí)間：2018-04-03 17:14

  本文選題：腎性貧血　切入點(diǎn)：網(wǎng)織紅細(xì)胞參數(shù)　出處：《新鄉(xiāng)醫(yī)學(xué)院》2017年碩士論文

【摘要】：目的通過(guò)觀察網(wǎng)織紅細(xì)胞系列參數(shù)變化的特點(diǎn),探討腎性貧血對(duì)網(wǎng)織紅細(xì)胞及相關(guān)參數(shù)的影響,為腎性貧血的初步診斷提供實(shí)驗(yàn)依據(jù)。方法選取36例慢性腎衰竭患者:肌酐(Cr)133μmol/L,尿素氮(BUN)8.2μmol/L,男性成人Hb120g/L,女性成人Hb110g/L,所有病例無(wú)鐵、葉酸、vitB12缺乏;無(wú)頑固性高血壓病史;無(wú)出血、感染和腫瘤等影響因素。同時(shí)選取門(mén)診健康體檢者30例為正常對(duì)照組;選取33例缺鐵性貧血患者做為貧血對(duì)照組,各組間年齡、性別無(wú)差異。所有研究對(duì)象均于清晨空腹抽取靜脈血2ml,2h內(nèi)送檢,4h內(nèi)檢測(cè)完畢。采用邁瑞B(yǎng)C-6800自動(dòng)血細(xì)胞分析儀檢測(cè)網(wǎng)織紅細(xì)胞六個(gè)參數(shù),包括網(wǎng)織紅細(xì)胞百分比(Ret%)、網(wǎng)織紅細(xì)胞絕對(duì)數(shù)(Ret#)、網(wǎng)織紅細(xì)胞未成熟比率(IRF)、網(wǎng)織紅細(xì)胞低熒光比率(LFR)、網(wǎng)織紅細(xì)胞中熒光比率(MFR)、網(wǎng)織紅細(xì)胞高熒光比率(HFR),并對(duì)幾組數(shù)據(jù)進(jìn)行比較分析。結(jié)果腎性貧血組與正常對(duì)照組比較:網(wǎng)織紅細(xì)胞絕對(duì)數(shù)(Ret#)、網(wǎng)織紅細(xì)胞未成熟比率(IRF)、網(wǎng)織紅細(xì)胞低熒光比率(LFR)和網(wǎng)織紅細(xì)胞中熒光比率(MFR)均低于正常對(duì)照組,其余各項(xiàng)指標(biāo)未見(jiàn)明顯變化。缺鐵性貧血組與正常對(duì)照組比較:網(wǎng)織紅細(xì)胞百分比(Ret%)、網(wǎng)織紅細(xì)胞未成熟比率(IRF)、網(wǎng)織紅細(xì)胞中熒光比率(MFR)、網(wǎng)織紅細(xì)胞高熒光比率(HFR)和網(wǎng)織紅細(xì)胞絕對(duì)數(shù)(Ret#)均高于正常對(duì)照組,網(wǎng)織紅細(xì)胞低熒光比率(LFR)低于正常對(duì)照組。腎性貧血組與缺鐵性貧血組比較:腎性貧血組的網(wǎng)織紅細(xì)胞百分比(Ret%)、網(wǎng)織紅細(xì)胞未成熟比率(IRF)、網(wǎng)織紅細(xì)胞中熒光比率(MFR)、網(wǎng)織紅細(xì)胞高熒光比率(HFR)和網(wǎng)織紅細(xì)胞絕對(duì)數(shù)(Ret#)幾項(xiàng)參數(shù)均低于缺鐵性貧血組,LFR高于缺鐵性貧血組。結(jié)論腎性貧血患者的網(wǎng)織紅細(xì)胞及其參數(shù)有其獨(dú)特性,可以作為初步診斷的依據(jù)。
[Abstract]:Objective to investigate the effects of renal anemia on reticulocyte and related parameters by observing the characteristics of reticulocyte series parameters, and to provide experimental evidence for the preliminary diagnosis of renal anemia.鏂規(guī)硶閫夊彇36渚嬫參鎬ц偩琛扮鎮(zhèn)ｈ，

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