心肌梗死患者急診經(jīng)皮冠狀動(dòng)脈介入術(shù)后腦鈉肽的變化及臨床特征
本文選題:急性心肌梗死 切入點(diǎn):經(jīng)皮冠狀動(dòng)脈介入術(shù) 出處:《中國(guó)現(xiàn)代醫(yī)學(xué)雜志》2017年27期 論文類型:期刊論文
【摘要】:目的探討ST抬高型心肌梗死(STEMI)和非ST抬高型心肌梗死(NSTEMI)急診經(jīng)皮冠狀動(dòng)脈介入術(shù)(PCI)后腦鈉肽(BNP)的變化和臨床特征。方法選取2015年1月-2015年12月急診入住該院的首發(fā)急性心肌梗死患者126例。根據(jù)患者入院心電圖變化分為STEMI組72例和NSTEMI組54例,并根據(jù)冠脈造影結(jié)果,分為1支冠脈病變組、2支冠脈病變組和3支冠脈病變組。選取正;颊20例為對(duì)照組,測(cè)定患者入院后24 h及術(shù)后7 d的BNP水平,比較各組間BNP水平的變化及其臨床特征。結(jié)果入院后24 h 1支病變組、2支病變組和3支病變組的STEMI組的BNP水平均高于NSTEMI組,差異有統(tǒng)計(jì)學(xué)意義(P0.05)。術(shù)后7 d 1支病變組的STEMI組和NSTEMI組的BNP水平比較差異無統(tǒng)計(jì)學(xué)意義(P0.05),2支病變組、3支病變組的STEMI組的BNP水平低于NSTEMI組,差異有統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論急性心肌梗死患者急診PCI后BNP水平的變化及相關(guān)臨床特征,有助于更為準(zhǔn)確的判斷病情、進(jìn)行危險(xiǎn)分層和評(píng)估長(zhǎng)期的預(yù)后等。
[Abstract]:Objective to investigate the changes and clinical characteristics of brain natriuretic peptide (BNPP) in patients with ST-elevation myocardial infarction (STEMI) and non-ST-elevation myocardial infarction (NSTEMI) after percutaneous coronary intervention (PCI). 126 patients with acute myocardial infarction were divided into two groups: STEMI group (n = 72) and NSTEMI group (n = 54). According to the results of coronary angiography, the patients were divided into one coronary artery disease group, two coronary artery lesion group and three coronary artery lesion group. 20 normal patients were selected as the control group. The BNP levels of the patients were measured 24 hours after admission and 7 days after operation. Results 24 hours after admission, the level of BNP in the STEMI group was higher than that in the NSTEMI group, and the BNP level in the STEMI group was higher than that in the NSTEMI group. There was no significant difference in BNP level between the STEMI group and the NSTEMI group on the 7th day after operation. The BNP level in the STEMI group was lower than that in the NSTEMI group. Conclusion the changes of BNP level and related clinical features in patients with acute myocardial infarction after emergency PCI are helpful for more accurate diagnosis, risk stratification and evaluation of long-term prognosis.
【作者單位】: 新疆醫(yī)科大學(xué)第一附屬醫(yī)院心臟中心;
【分類號(hào)】:R542.22
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