本文選題：高敏肌鈣蛋白T　切入點：慢性心力衰竭　出處：《中國老年學雜志》2017年05期 　論文類型：期刊論文

【摘要】：目的研究老年患者高敏肌鈣蛋白(hs-cTn)T升高程度在慢性心力衰竭(CHF)與急性心肌梗死(AMI)鑒別診斷中的價值。方法372例老年CHF患者作為CHF組296例老年AMI患者作為AMI組,并以238例健康老年體檢人群為對照組,比較三組hs-cTnT水平。受試者工作特征(ROC)曲線分析hs-cTnT對CHF的診斷切點。結(jié)果 hs-cTnT在AMI組(3.245±1.356)ng/ml、CHF組(0.298±0.124)ng/ml及對照組(0.009±0.003)ng/ml的血漿濃度依次顯著降低(P0.05);ROC曲線評價hs-cTnT對CHF的診斷價值,曲線下面積(AUC)為0.746(95%CI:0.696~0.864).診斷范圍為0.09~2.38ng/ml;對AMI的診斷價值,AUC為0.865(95%CI:0.715~0.965),診斷切點為2.38ng/ml;不同美國紐約心臟病學會(NYHA)心功能CHF患者及對照組hs-cTnT比較,Ⅳ級(0.369±0.117)ng/ml、Ⅲ級(0.267±0.102)ng/ml、Ⅱ級(0.142±0.084)ng/ml及對照組(0.009±0.003)ng/ml血漿濃度依次降低,hs-cTnT與NYHA心功能經(jīng)Pearson等級相關(guān)分析呈正相關(guān)(r=0.825,P0.05)。結(jié)論hs-cTnT作為心肌損傷特異性標志物在CHF及AMI的早期鑒別及CHF病情評估有重要應用價值。
[Abstract]:Objective to study the value of the elevation of troponin cTnTnTnTc in the elderly patients with chronic heart failure (CHF) and acute myocardial infarction (AMI). Methods 372 elderly patients with CHF were treated as CHF group, 296 elderly AMI patients as AMI group. 238 healthy elderly people were taken as control group. The diagnostic point of hs-cTnT for CHF was analyzed by comparing the three groups of hs-cTnT levels. Results the plasma concentrations of hs-cTnT in AMI group (3.245 鹵1.356g / ml) and control group (0.298 鹵0.124ng / ml) and control group (0.009 鹵0.003ng / ml) were significantly lower than those in control group (P 0.05ng / ml) to evaluate the value of hs-cTnT in the diagnosis of CHF. Under the curve, the area under the curve is 0.746 / 95 CI: 0.696 / 0.864. The diagnostic range is 0.09 / 2.38 ng / ml; the diagnostic value for AMI is 0.865 95% CI: 0.715 / 0.965g / ml, and the diagnostic cutoff point is 2.38 ng / ml; the hs-cTnT of CHF patients and control group is different from that of the American New York Cardiac Association (NYHA). The plasma concentrations of grade 鈪，

本文編號：1557702