本文關(guān)鍵詞： 中心動脈壓 白大衣現(xiàn)象 高血壓　出處：《福建醫(yī)科大學(xué)》2015年碩士論文　論文類型：學(xué)位論文

【摘要】：目的:探討高血壓病患者中心動脈壓是否存在白大衣現(xiàn)象。方法:共收集44位根據(jù)診室血壓(OBP)新診斷的高血壓病患者,年齡在19-80歲之間,其中男性20名,女性24名。所有患者均被要求自初診第一日起自測家庭血壓1周。在初診當(dāng)日,所有患者均無創(chuàng)測量中心動脈壓(CAP)及脈搏波分析。根據(jù)家庭血壓(HBP)結(jié)果將所有患者分為兩組:持續(xù)性高血壓組(SHT組,n=28)和白大衣高血壓組(WCH組,n=16);根據(jù)OBP和HBP之間的差值,再將SHT組分為:白大衣效應(yīng)組(WCE組,n=15)和非白大衣效應(yīng)組(NWCE組,n=13)。計(jì)算各組中心動脈收縮壓(CASP)與HSBP的差值(CHSBP),作為判斷中心動脈壓是否存在白大衣現(xiàn)象的指標(biāo)。結(jié)果:(1)分別計(jì)算各組間的OSBP、檢查室收縮壓(ESBP)、HSBP與CASP的差值,分別用OCSBP、ECSBP、HCSBP表示。結(jié)果發(fā)現(xiàn),只有HCSBP在WCH組較SHT組低(-1.97±14.54比7.07±11.18 mm Hg,p=0.026)、在WCE組明顯小于NWCE組(2.33±8.59比12.54±11.60 mm Hg,p=0.013)。而OCSBP、ECSBP在各組間無顯著差異(p0.05)。(2)為進(jìn)一步了解各種血壓測量方式的白大衣效應(yīng)程度,我們分別求得OSBP、ESBP、CASP與HSBP的差值,分別用OHSBP、EHSBP、CHSBP表示。結(jié)果發(fā)現(xiàn)在WCH組OHSBP、EHSBP、CHSBP均明顯高于SHT組(OHSBP:21.88±11.85比11.98±11.01 mm Hg,p=0.008;EHSBP:10.97±13.55比2.28±11.33 mm Hg,p=0.028;CHSBP:1.97±14.54比-7.07±11.18 mm Hg,p=0.026)。在校正完身高、BMI、年齡、PWV、ABI、早發(fā)心血管疾病家族史后,上述各差異仍具有統(tǒng)計(jì)學(xué)意義(p0.05)。同時,不論在WCH組或是SHT組均可觀察到OHSBPEHSBPCHSBP(p0.05)。(3)相關(guān)分析發(fā)現(xiàn)CASP與同步測量的外周收縮壓密切相關(guān)(r=0.91,p0.001)。結(jié)論:高血壓病患者中心動脈壓可能存在白大衣現(xiàn)象,其白大衣效應(yīng)程度,即血壓升高的幅度,低于診室和檢查室血壓的白大衣效應(yīng)程度。
[Abstract]:Objective: to investigate the existence of white coat in central arterial pressure in patients with hypertension. Methods: a total of 44 newly diagnosed hypertension patients, aged between 19 and 80 years, including 20 men, were collected according to the blood pressure in the clinic. 24 women. All patients were asked to test their blood pressure for one week from 1st. All the patients were divided into two groups according to the results of family blood pressure (HBP): continuous hypertension group (SHT group) and white coat hypertension group (WCH group), according to the difference between OBP and HBP. The SHT components were divided into white coat effect group and non-white coat effect group. The difference between central arterial systolic pressure and HSBP was calculated as an index to judge the existence of white coat phenomenon. The difference between OSBP and CASP was calculated. The results showed that only HCSBP in WCH group was lower than that in SHT group (-1.97 鹵14.54 vs 7.07 鹵11.18 mm), and in WCE group was significantly smaller than that in NWCE group (2.33 鹵8.59 vs 12.54 鹵11.60 mm). We obtained the difference between HSBP and ESBP, respectively. The results showed that the difference between WCH group and HSBP group was significantly higher than that in SHT group (21.88 鹵11.85 vs 11.98 鹵11.01 mm vs 11.98 鹵11.01 mm vs 11.98 鹵11.01 mm vs 10.97 鹵13.55 vs 2.28 鹵11.33 mm vs 2.28 鹵11.33 mm vs 1.97 鹵14.54 vs -7.07 鹵11.18 mm). The above differences are still statistically significant (p 0.05). At the same time, OHSBPEHSBPCHSBP (p0.05) correlation analysis showed that CASP was closely related to the measured peripheral systolic blood pressure (CASP). Conclusion: the central arterial pressure of essential hypertension patients may have white coat phenomenon and the degree of white coat effect. The range of elevated blood pressure was lower than the white coat effect of blood pressure in the clinic and examination room.
【學(xué)位授予單位】：福建醫(yī)科大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2015
【分類號】：R544.1

【共引文獻(xiàn)】

相關(guān)期刊論文 前1條

1 奧日瀚;任鴻坤;;監(jiān)測中心動脈壓對預(yù)防頸動脈斑塊形成的研究進(jìn)展[J];內(nèi)蒙古醫(yī)科大學(xué)學(xué)報;2015年S1期

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本文編號：1518085