目的:檢測并分析短節(jié)段Barrett’s食管（BE）患者的餐后近端胃酸袋（PPGAP）的特點,并分析其與胃食管酸反流的相關(guān)性。創(chuàng)新點:PPGAP可能是胃食管反流病的病理因素之一,引起廣泛關(guān)注,而BE患者的PPGAP特點及與反流的相關(guān)性尚無報道。方法:15名短節(jié)段BE患者和15名健康志愿者分別以牽拉法檢測PPGAP的發(fā)生時間、長度、最低pH值和平均pH值。BE患者完成Gerd Q問卷調(diào)查和24 h食管pH監(jiān)測。結(jié)論:短節(jié)段BE患者普遍存在PPGAP,同時PPGAP的長度和酸度與其胃食管酸反流周期數(shù)、De Meester評分和Gerd Q評分具有相關(guān)性。 

【文章來源】：Journal of Zhejiang University-Science B（Biomedicine & Biotechnology）. 2020,21(07)SCICSCD

【文章頁數(shù)】：9 頁

【文章目錄】：
1 Introduction
2 Materials and methods
    2.1 Subjects
    2.2 Gerd Q
    2.3 Detection of PPGAPs
        2.3.1 Detection of p H changes in the distal esophagus and proximal stomach on fasting
        2.3.2 Postprandial p H changes in the distal esophagus and proximal stomach
    2.4 Esophageal 24-h p H monitoring
    2.5 Statistical analysis
3 Results
    3.1 Comparison of PPGAPs between patients with BE and healthy individuals
    3.2 PPGAP in patients with BE
    3.3 Correlations among the appearance time,length,and lowest p H of PPGAP in patients with BE
    3.4 Correlation between PPGAP and gastroesoph-ageal acid reflux in patients with BE
4 Discussion
Contributors
Compliance with ethics guidelines



本文編號：3440262